Results 41 to 50 of about 2,385 (164)
Adaptive Evolution of a Tagged Chimeric Gammaretrovirus: Identification of Novel cis-Acting Elements that Modulate Splicing [PDF]
Journal of Molecular Biology, 2007 Retroviruses are well known for their ability to incorporate envelope (Env) proteins from other retroviral strains and genera, and even from other virus families. This characteristic has been widely exploited for the generation of replication-defective retroviral vectors, including those derived from murine leukemia virus (MLV), bearing heterologous ...
Christopher R. Logg +3 more
openalex +3 more sources
Next-Generation Sequencing of Prostate Tumors Provides Independent Evidence of Xenotropic Murine Leukemia Virus-Related Gammaretrovirus Contamination [PDF]
Journal of Clinical Microbiology, 2011 Fan Mo +7 more
semanticscholar +2 more sources
Feline Leukemia Virus in Cats: A Novel Rapid ELISA Assay for p27 Antigen Detection. [PDF]
Vet Med IntFeline leukemia virus (FeLV) is an oncogenic immunosuppressive virus belonging to the Retroviridae family and one of the most common causes of a major infectious disorder in cats that can lead to potentially fatal associated diseases with a worse prognosis.
Ferrero I +4 more
europepmc +2 more sources
Molecular Therapy, 2006 The recent recognition that recombinant retrovirus vectors can induce oncogenic transformation has stimulated much interest in the pattern of vector integration sites. We report here on the integration pattern of a gammaretrovirus reporter vector following transduction and ex vivo culture of primary mouse bone marrow progenitor cells in the absence and
Mari Aker +4 more
openalex +4 more sources
Viral vector‐based cancer treatment and current clinical applications
MedComm – Oncology, Volume 2, Issue 4, December 2023., 2023 Adenovirus, adeno‐associated virus, herpes simplex virus, and retrovirus have been utilized for cancer treatment. Ex vivo treatment: cells isolated from the patients are genetically modified by viral vectors and then transfused back into patients.
Lingwan Xie +6 more
wiley +1 more source
A natural human retrovirus efficiently complements vectors based on murine leukemia virus. [PDF]
PLoS ONE, 2008 Murine Leukemia Virus (MLV) is a rodent gammaretrovirus that serves as the backbone for common gene delivery tools designed for experimental and therapeutic applications.
Beihua Dong +2 more
doaj +1 more source
Occurrence of Typical Domestic Animal Viruses in Wild Carnivorans: An Emerging Threat to the Conservation of Endangered Species. [PDF]
Transbound Emerg DisWild species are susceptible to several typical domestic animal pathogens, and the increasingly close contact between these groups is a predictive factor for disease exposure. Some viruses are important and old‐known, and others are emerging or reemerging for domestic carnivorans and have been identified as threats to the conservation of wild mammals ...
Martins NB +8 more
europepmc +2 more sources
Multiple infections of zoonotic pathogens in wild Brandt's voles (Lasiopodomys brandtii)
Veterinary Medicine and Science, Volume 9, Issue 5, Page 2201-2211, September 2023., 2023 Our research revealed the viral and bacterial diversity in wild Brandt's voles. The characterization and distinctive lineage of some rodent‐specific viruses (Cytomegalovirus, PestVs and Lentiviruses) and rodent‐borne bacteria (Leptospira interrogans and Vibrio cholerae) indicates that wild Brandt's voles may harbor a diversity of viruses and bacteria ...
Yongman Guo +6 more
wiley +1 more source
mLife, Volume 2, Issue 2, Page 201-208, June 2023., 2023 Abstract Mammalian endogenous retroviruses (ERVs) are ancient retroviruses that have been integrated into genomes. ERVs were believed to be inactive until the discovery of ERV transcription in the mouse genome. However, the transcription level and function of ERV elements in mammalian genomes are not well understood.
Zheng Li +5 more
wiley +1 more source