Results 61 to 70 of about 2,385 (164)
The Human Lung Adenocarcinoma Cell Line EKVX Produces an Infectious Xenotropic Murine Leukemia Virus
Viruses, 2011 The cell lines of the NCI-60 panel represent different cancer types and have been widely utilized for drug screening and molecular target identification.
Xiang Zhang +4 more
doaj +1 more source
American Journal of Hematology, Volume 96, Issue 10, Page 1295-1312, October 2021., 2021 Abstract Chimeric antigen receptor (CAR)‐T cell therapies have improved the outcome for many patients with relapsed or refractory aggressive B‐cell lymphomas. In 2017, axicabtagene ciloleucel and soon after tisagenlecleucel became the first approved CAR‐T cell products for patients with high‐grade B‐cell lymphomas or diffuse large B‐cell lymphoma ...
Jason R. Westin +6 more
wiley +1 more source
A cautionary tale of virus and disease
BMC Biology, 2010 The recent identification of the gammaretrovirus XMRV and a second gammaretrovirus of a different subtype in chronic fatigue syndrome has aroused much interest, not least among sufferers.
Weiss Robin A
doaj +1 more source
INSPIIRED: Quantification and Visualization Tools for Analyzing Integration Site Distributions
Molecular Therapy: Methods & Clinical Development, 2017 Analysis of sites of newly integrated DNA in cellular genomes is important to several fields, but methods for analyzing and visualizing these datasets are still under development.
Charles C. Berry +16 more
doaj +1 more source
Viruses, 2014 Previously we reported that nuclear export of both unspliced and spliced murine leukemia virus (MLV) transcripts depends on the nuclear export factor (NXF1) pathway.
Toshie Sakuma +2 more
doaj +1 more source
An XMRV Derived Retroviral Vector as a Tool for Gene Transfer
Virology Journal, 2011 Background Retroviral vectors are widely used tools for gene delivery and gene therapy. They are useful for gene expression studies and genetic manipulation in vitro and in vivo.
Rojas-Martinez Augusto +2 more
doaj +1 more source
Biochemical characterization of novel retroviral integrase proteins. [PDF]
PLoS ONE, 2013 Integrase is an essential retroviral enzyme, catalyzing the stable integration of reverse transcribed DNA into cellular DNA. Several aspects of the integration mechanism, including the length of host DNA sequence duplication flanking the integrated ...
Allison Ballandras-Colas +4 more
doaj +1 more source
Viruses, 2022 To complete their replication cycle, retroviruses need to integrate a DNA copy of their RNA genome into a host chromosome. Integration site selection is not random and is driven by multiple viral and cellular host factors specific to different classes of
Eline Pellaers +3 more
doaj +1 more source
, 2022 HemaSphere, Volume 6, Issue S3, Page 998-999, June 2022.
S. Fried +12 more
wiley +1 more source
DNA extraction columns contaminated with murine sequences. [PDF]
PLoS ONE, 2011 Sequences of the novel gammaretrovirus, xenotropic murine leukemia virus-related virus (XMRV) have been described in human prostate cancer tissue, although the amounts of DNA are low. Furthermore, XMRV sequences and polytropic (p) murine leukemia viruses
Otto Erlwein +5 more
doaj +1 more source