Results 71 to 80 of about 4,044 (208)
An XMRV Derived Retroviral Vector as a Tool for Gene Transfer
Virology Journal, 2011 Background Retroviral vectors are widely used tools for gene delivery and gene therapy. They are useful for gene expression studies and genetic manipulation in vitro and in vivo.
Rojas-Martinez Augusto +2 more
doaj +1 more source
Viruses, 2022 To complete their replication cycle, retroviruses need to integrate a DNA copy of their RNA genome into a host chromosome. Integration site selection is not random and is driven by multiple viral and cellular host factors specific to different classes of
Eline Pellaers +3 more
doaj +1 more source
Crystal structure of xenotropic murine leukaemia virus-related virus (XMRV) ribonuclease H [PDF]
, 2014 RNase H (retroviral ribonuclease H) cleaves the phosphate backbone of the RNA template within an RNA/DNA hybrid to complete the synthesis of double-stranded viral DNA.
Chung, Bong Hyun +8 more
core +1 more source
Is gibbon ape leukaemia virus still a threat? [PDF]
, 2016 In the late 1960s and early 1970s, an outbreak of lymphoma and leukaemia in gibbons (Hylobatidae), attributed to the retrovirus gibbon ape leukaemia virus (GALV), was widely reported in the literature.
Callahan R +7 more
core +1 more source
, 2022 HemaSphere, Volume 6, Issue S3, Page 998-999, June 2022.
S. Fried +12 more
wiley +1 more source
Polymicrobial periodontal disease triggers a wide radius of effect and unique virome. [PDF]
, 2020 Periodontal disease is a microbially-mediated inflammatory disease of tooth-supporting tissues that leads to bone and tissue loss around teeth. Although bacterially-mediated mechanisms of alveolar bone destruction have been widely studied, the effects of
Gao, Li +12 more
core
Protease Cleavage Leads to Formation of Mature Trimer Interface in HIV-1 Capsid [PDF]
, 2012 During retrovirus particle maturation, the assembled Gag polyprotein is cleaved by the viral protease into matrix (MA), capsid (CA), and nucleocapsid (NC) proteins.
Angela M. Gronenborn +10 more
core +7 more sources
Gammaretroviruses tether to mitotic chromatin by directly binding nucleosomal histone proteins
Microbial Cell, 2018 The gammaretroviral gag cleavage product, p12, is essential for replication at both early and late stages of the virus life cycle. During the early stage of infection, the viral core is released into the cytoplasm, the viral RNA genome is reversed ...
Madushi Wanaguru, Kate N. Bishop
doaj +1 more source
DNA extraction columns contaminated with murine sequences. [PDF]
PLoS ONE, 2011 Sequences of the novel gammaretrovirus, xenotropic murine leukemia virus-related virus (XMRV) have been described in human prostate cancer tissue, although the amounts of DNA are low. Furthermore, XMRV sequences and polytropic (p) murine leukemia viruses
Otto Erlwein +5 more
doaj +1 more source