Results 71 to 80 of about 2,385 (164)
Molecular detection of feline leukemia virus in clinically ill cats in Klang Valley, Malaysia [PDF]
Veterinary World, 2021 Background and Aim: Feline leukemia virus (FeLV) is classified as Retroviridae gammaretrovirus. FeLV occurs worldwide, including Malaysia. Thus far, only one decade-old study on molecular characterization of Malaysian FeLV isolates exists, which resulted
Kunambiga Mummoorthy +7 more
doaj +1 more source
Frontiers in Oncology, 2013 Infection of xenotransplanted human cells by xenotropic retroviruses is a known phenomenon in the scientific literature, with examples cited since the early 1970’s. However, arguably, until recently, the importance of this phenomenon had not been largely
Heidi Anne Hempel +6 more
doaj +1 more source
Gammaretroviruses tether to mitotic chromatin by directly binding nucleosomal histone proteins
Microbial Cell, 2018 The gammaretroviral gag cleavage product, p12, is essential for replication at both early and late stages of the virus life cycle. During the early stage of infection, the viral core is released into the cytoplasm, the viral RNA genome is reversed ...
Madushi Wanaguru, Kate N. Bishop
doaj +1 more source
Advances in Virology, 2011 Xenotropic-murine-leukemia-virus-related virus (XMRV) was the first gammaretrovirus to be reported in humans. The sequence similarity between XMRV and murine leukemia viruses (MLVs) was consistent with an origin of XMRV from one or more MLVs present as ...
Oya Cingöz, John M. Coffin
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Lack of Detection of Xenotropic Murine Leukemia Virus-Related Virus in HIV-1 Lymphoma Patients
Advances in Virology, 2011 Xenotropic murine leukemia virus-related virus (XMRV) is a gammaretrovirus reported to be associated with human prostate cancer and chronic fatigue syndrome. Since retroviruses cause various cancers, and XMRV replication might be facilitated by HIV-1 co-
Krista A. Delviks-Frankenberry +5 more
doaj +1 more source
Gammaretroviral vector encoding a fluorescent marker to facilitate detection of reprogrammed human fibroblasts during iPSC generation [PDF]
PeerJ, 2013 Induced pluripotent stem cells (iPSCs) are becoming mainstream tools to study mechanisms of development and disease. They have a broad range of applications in understanding disease processes, in vitro testing of novel therapies, and potential utility in
Narasimhachar Srinivasakumar +7 more
doaj +2 more sources
Gammaretroviral Vectors: Biology, Technology and Application
Viruses, 2011 Retroviruses are evolutionary optimized gene carriers that have naturally adapted to their hosts to efficiently deliver their nucleic acids into the target cell chromatin, thereby overcoming natural cellular barriers.
Axel Schambach +3 more
doaj +1 more source
Xenotropic Mouse Gammaretroviruses Isolated from Pre-Leukemic Tissues Include a Recombinant
Viruses, 2018 Naturally-occurring lymphomagenesis is induced by mouse leukemia viruses (MLVs) carried as endogenous retroviruses (ERVs). Replicating the ecotropic MLVs recombines with polytropic (P-ERVs) and xenotropic ERVs (X-ERVs) to generate pathogenic viruses with
Devinka Bamunusinghe +3 more
doaj +1 more source
Australian Veterinary Journal, EarlyView.Progressive feline leukaemia virus (FeLV) infection dramatically shortens the lives of infected cats, causing acquired immunodeficiency, aplastic anaemia, lymphoma, leukaemia and other myeloproliferative diseases. The potential impact of regressive FeLV infection on the development of disease remains largely unknown, although there is evidence it ...
ME Westman +6 more
wiley +1 more source