Results 41 to 50 of about 62,914 (267)

Asymptomatic moyamoya syndrome, atlantoaxial subluxation and basal ganglia calcification in a child with Down syndrome [PDF]

Korean Journal of Pediatrics, 2013
Down syndrome, the most common chromosomal abnormality, may be associated with various neurologic complications such as moyamoya syndrome, cervical spinal cord compression due to atlantoaxial subluxation, and basal ganglia damage, as well as epileptic ...
Kyung Yeon Lee, Kun-Soo Lee, Young Cheol Weon   +2 more
doaj   +1 more source

Expression Pattern of p62 in Primary Age-Related Tauopathy: Staging of p62 in PART

Frontiers in Aging Neuroscience, 2022
The present study analyzed the distribution pattern of p62 immunoreactivity in brains of primary age-related tauopathy (PART) and Braak NFT matched pre-AD and Alzheimer’s disease (AD) patients using immunohistochemistry in combination with semi ...
Xin Wang, Xin Wang, Lei Zhang, Lei Zhang, Hui Lu, Juanli Wu, Huazheng Liang, Bing Sun, Keqing Zhu, Keqing Zhu   +9 more
doaj   +1 more source

Understanding the Effects of Conductive Polymer Electrode Coating on Recorded Neural Signals

Advanced Healthcare Materials, EarlyView.
Conductive polymer coatings are widely explored to improve the quality of signals recorded with chronically implanted neural electrodes, offering enhanced biocompatibility along with reduced electrode impedance. Combining computational modelling and data from PEDOT:PTS coated and PtIr electrodes in rats, we show that improvements in signal quality with
Karthik Sridhar, Judith Evers, Alexandre Trotier, Manus Biggs, Madeleine M. Lowery   +4 more
wiley   +1 more source

Progress of dorsal root ganglia in mechanism of pain

Chinese Journal of Contemporary Neurology and Neurosurgery, 2018
Dorsal root ganglia (DRG) neurons are the primary afferent neurons of algaesthesis of trunk and extremities. DRG transmits and accommodates sensations and accepts and conveys nociception, so it plays an important role in the mechanism of pain.
Jing-zhi LIU
doaj   +1 more source

Piezo2 Mediates a Vicious Cycle of “Mechanical Homeostasis Imbalance—Inflammation” in Sensory Nerves and the Cartilage Endplate

Advanced Science, EarlyView.
In a lumbar spine instability model, dorsal root ganglion cells mediate the perception of relevant mechanical stresses through Piezo2 and subsequently release CGRP. CGRP activates the NF‐κB signaling pathway in cartilage endplate cells through the receptor RAMP1.
Hanpeng Xu, Wen Geng, Zhi Du, Yifan Du, Di Wu, Bide Tong, Huaizhen Liang, Xingyu Zhou, Zixuan Ou, Junyu Wei, Kun Wang, Yu Song, Wenbin Hua, Yan Xu, Wencan Ke, Bingjin Wang, Cao Yang   +16 more
wiley   +1 more source

Herpes zoster in the T1 dermatome presenting with Horner’s syndrome, radicular weakness, and postherpetic neuralgia

International Medical Case Reports Journal, 2008
W Oliver Tobin1, Byron R Spencer2, Bart M Demaerschalk21Department of Neurology, Adelaide and Meath Hospital, Dublin, incorporating the National Children’s Hospital, Ireland; 2Department of Neurology, Mayo Clinic Arizona, USAAbstract: Herpes ...
W Oliver Tobin, Byron R Spencer, Bart M Demaerschalk   +2 more
doaj  

CONFRONTING SUBSURFACE CISTERNAE IN CHICK EMBRYO SPINAL GANGLIA [PDF]

The Journal of Cell Biology, 1968
Subsurface cisternae (SSC's) have been described in several types of conduct ing tissue (1-6), and in a cul tured neoplastic cell line (7). In some of these cases (2, 3, 7), paired SSC's appeared opposite each other in apposing cells, a configurat ion referred to as subsurface confronting cisternae (7). This note demonstra tes the existence of SSC's in
openaire   +2 more sources

Deciphering and Targeting the Schwannoma‐Neuron‐Macrophage Crosstalk for the Treatment of Schwannomatosis and Associated Pain

Advanced Science, EarlyView.
We established patient‐derived SWN cell lines and orthotopic PDX models that recapitulate patient pain phenotypes, alongside a novel intravital DRG imaging platform to track macrophage infiltration and neuronal pain responses. Using these models, we define HMGB1–CCL2–IL‐6 signaling crosstalk driving pain and identify EGF signaling as a key regulator of
Zhenzhen Yin, Limeng Wu, Yanling Zhang, Yao Sun, Grace Y. Lee, Simeng Lu, Xing Gao, John W. Chen, Sonu Subudhi, William Ho, Chao Zhu, Jun Ren, Gino B. Ferraro, Alona Muzikansky, Anat Stemmer‐Rachamimov, Jianren Mao, Scott R. Plotkin, Lei Xu   +17 more
wiley   +1 more source

The control of alternative splicing by SRSF1 in myelinated afferents contributes to the development of neuropathic pain

Neurobiology of Disease, 2016
Neuropathic pain results from neuroplasticity in nociceptive neuronal networks. Here we demonstrate that control of alternative pre-mRNA splicing, through the splice factor serine-arginine splice factor 1 (SRSF1), is integral to the processing of ...
Richard P. Hulse, Robert A.R. Drake, David O. Bates, Lucy F. Donaldson   +3 more
doaj   +1 more source

Enhanced T-type calcium channel 3.2 activity in sensory neurons contributes to neuropathic-like pain of monosodium iodoacetate-induced knee osteoarthritis

Molecular Pain, 2020
The monosodium iodoacetate knee osteoarthritis model has been widely used for the evaluation of osteoarthritis pain, but the pathogenesis of associated chronic pain is not fully understood.
Seung Min Shin PhD, Yongsong Cai MD, PhD, Brandon Itson-Zoske BS, Chensheng Qiu MD, Xu Hao MD, PhD, Hongfei Xiang MD, PhD, Quinn H Hogan MD, Hongwei Yu MD   +7 more
doaj   +1 more source