Results 21 to 30 of about 62,914 (267)

Sources of the motor and somatic sensory innervation of the trapezius muscle in the rat

Veterinární Medicína, 2010
The study was carried out on nine sexually mature male rats of the Wistar breed weighing approximately 250 g each. Animals were anaesthetized with thiopental sodium injected intraperitoneally (30 mg/kg of body weight). The animals were then injected with
W. Sienkiewicz, A. Dudek
doaj   +1 more source

A video protocol for rapid dissection of mouse dorsal root ganglia from defined spinal levels

BMC Research Notes, 2020
Objective Dorsal root ganglia (DRG) are heterogeneous assemblies of assorted sensory neuron cell bodies found in bilateral pairs at every level of the spinal column.
James N. Sleigh, Steven J. West, Giampietro Schiavo   +2 more
doaj   +1 more source

Rat spinal ganglia in assessment of protective action of antioxidants: A morphological study

Medicina, 2017
Background and objective: Mercury pollution is one of the most pressing environmental problems. Therefore, the impact of mercury on human body, the nervous system in particular, remains topical.
Liudmyla M. Sokurenko, Mariya O. Savchyna, Viktor I. Litus, Rostyslav F. Kaminsky, Yurii B. Ehaikovsky   +4 more
doaj   +1 more source

Degeneration of spinal ganglion and segmental apparatus of the spinal neurons in sciatic nerve injury: an experimental study

Russian Open Medical Journal, 2021
Objective — To investigate the extent of degenerative changes in neurons of spinal ganglion and segmental apparatus in various injuries to sciatic nerve in the experiment on white rats.
Vladimir S. Tolkachev, Sergey P. Bazhanov, Olga V. Matveeva, Galina A. Korshunova, Stanislav D. Shuvalov, Valdimir Yu. Ulyanov, Vladimir V. Ostrovskij   +6 more
doaj   +1 more source

Single-cell RNA sequencing of the post–spinal cord injury dorsal root ganglia in cynomolgus monkeys: Elucidation of the cellular immune microenvironment of the central nervous system

Neural Regeneration Research
Few studies have investigated alterations in the immune cell microenvironment of the dorsal root ganglia following spinal cord injury and whether these modifications facilitate axonal regeneration.
Yiming Ren, Bo Li, Bo Yang, Baoyou Fan, Shenghui Huang, Guidong Shi, Liang Liu, Zhijian Wei, Shiqing Feng   +8 more
doaj   +1 more source

Gastric electrical stimulation decreases gastric distension-induced central nociception response through direct action on primary afferents. [PDF]

PLoS ONE, 2012
BACKGROUND & AIMS: Gastric electrical stimulation (GES) is an effective therapy to treat patients with chronic dyspepsia refractory to medical management. However, its mechanisms of action remain poorly understood.
Wassila Ouelaa, Ibtissem Ghouzali, Ludovic Langlois, Serguei Fetissov, Pierre Déchelotte, Philippe Ducrotté, Anne Marie Leroi, Guillaume Gourcerol   +7 more
doaj   +1 more source

Neurophysiology of the pedunculopontine tegmental nucleus

Neurobiology of Disease, 2019
The interest in the pedunculopontine tegmental nucleus (PPTg), a structure located in the brainstem at the level of the pontomesencephalic junction, has greatly increased in recent years because it is involved in the regulation of physiological functions
F. Vitale, A. Capozzo, P. Mazzone, E. Scarnati   +3 more
doaj   +1 more source

Linking neurogenesis, oligodendrogenesis, and myelination defects to neurodevelopmental disruption in primary mitochondrial disorders

FEBS Letters, EarlyView.
Mitochondrial remodeling shapes neural and glial lineage progression by matching metabolic supply with demand. Elevated OXPHOS supports differentiation and myelin formation, while myelin compaction lowers mitochondrial dependence, revealing mitochondria as key drivers of developmental energy adaptation.
Sahitya Ranjan Biswas, Porter L. Tomsick, Alicia M. Pickrell, Paul D. Morton   +3 more
wiley   +1 more source

Deciphering transcriptional plasticity in pancreatic ductal adenocarcinoma reveals alterations in sensory neuron innervation

Molecular Oncology, EarlyView.
Pancreatic sensory neurons innervating healthy and PDAC tissue were retrogradely labeled and profiled by single‐cell RNA sequencing. Tumor‐associated innervation showed a dominant neurofilament‐positive subtype, altered mitochondrial gene signatures, and reduced non‐peptidergic neurons.
Elena Genova, Michele Montrone, Uday Rangaswamy, Francesco Diversi, Irene Schiavo, Denise Ferrarini, Roberta Di Florio, Irene Longo, Michele Coscia, Nicola Zamboni, Giorgia Demontis, Lisa Veghini, Vincenzo Corbo, Remo Sanges, Paul Heppenstall   +14 more
wiley   +1 more source

Disengaging spinal afferent nerve communication with the brain in live mice

Communications Biology, 2022
A surgical method in mice can selectively remove dorsal root ganglia (DRG) at specific spinal levels without interfering with other nerves, providing insight on thoracolumbar vs. lumbosacral DRG contributions to pain signalling and behaviour.
Melinda A. Kyloh, Timothy J. Hibberd, Joel Castro, Andrea M. Harrington, Lee Travis, Kelsi N. Dodds, Lukasz Wiklendt, Stuart M. Brierley, Vladimir P. Zagorodnyuk, Nick J. Spencer   +9 more
doaj   +1 more source