Expression of neuropeptides – galanin and Reg2 - in subcategories of nociceptors after nerve injury [PDF]
, 2010 PhDNeuropeptides show dynamic changes in expression after nerve injury, and have been implicated in chronic pain states. I sought to compare expression of two peptides which are upregulated after nerve injury, galanin and Reg2, and to determine the ...
Burrows, Karen Lynne
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A functional motor unit in the culture dish : co-culture of spinal cord explants and muscle cells [PDF]
, 2012 Human primary muscle cells cultured aneurally in monolayer rarely contract spontaneously because, in the absence of a nerve component, cell differentiation is limited and motor neuron stimulation is missing(1). These limitations hamper the in vitro study
Handschin, Christoph +2 more
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Basal ganglia-spinal cord pathway that commands locomotor gait asymmetries in mice. [PDF]
Nat NeurosciThe basal ganglia are essential for executing motor actions. How the basal ganglia engage spinal motor networks has remained elusive. Medullary Chx10 gigantocellular (Gi) neurons are required for turning gait programs, suggesting that turning gaits ...
Cregg JM, Sidhu SK, Leiras R, Kiehn O.
europepmc +2 more sources
Presynaptically localized cyclic GMP-dependent protein kinase 1 is a key determinant of spinal synaptic potentiation and pain hypersensitivity [PDF]
, 2012 Synaptic long-term potentiation (LTP) at spinal neurons directly communicating pain-specific inputs from the periphery to the brain has been proposed to serve as a trigger for pain hypersensitivity in pathological states.
Todd, A. J. +103 more
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Gene profiling of identified neurons to dissect molecular mechanisms involved in spinal reflex assembly [PDF]
, 2010 The central question during my PhD studies was to understand the molecular mechanisms and genetic cascades controlling the sequential specification of distinct classes of dorsal root ganglia (DRG) sensory neurons, with a particular focus on genes ...
Friese, Andreas
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Nuclear expression of PG-21, SRC-1, and pCREB in regions of the lumbosacral spinal cord involved in pelvic innervation in young adult and aged rats [PDF]
, 2012 In rats, ageing results in dysfunctional patterns of micturition and diminished sexual reflexes that may reflect degenerative changes within spinal circuitry.
Ranson, R. N. +7 more
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Identification of different types of spinal afferent nerve endings that encode noxious and innocuous stimuli in the large intestine using a novel anterograde tracing technique. [PDF]
PLoS ONE, 2014 In mammals, sensory stimuli in visceral organs, including those that underlie pain perception, are detected by spinal afferent neurons, whose cell bodies lie in dorsal root ganglia (DRG).
Nick J Spencer +2 more
doaj +1 more source
Comparative study of heparin- and toluidine blue positive mast cells in porcine lumbar spinal ganglia [PDF]
Bulgarian Journal of Veterinary Medicine, 2018 In the present study, toluidine blue for metachromasia and berberine sulfate for heparin fluorescence were used to determine the localisation and distribution of mast cells as well as the percent of hepa-rin-positive cells (MCH) in normal lumbar spinal ...
A. Vodenicharov +3 more
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Frontiers in Pediatrics, 2023 BackgroundThe need to search for ganglia in the terminal rectum/fistula of complex anorectal malformations (ARMs) remains controversial. This study aims to evaluate the relationship between ganglia absence in the terminal rectum/fistula and defecation ...
Wei Feng +8 more
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Brain Sciences, 2023 Huntingtin-associated protein 1 (HAP1) is a determinant marker for the stigmoid body (STB), a neurocytoplasmic physiological inclusion. STB/HAP1 enriched areas in the brain/spinal cord are usually protected from neurodegenerative diseases, whereas the ...
Md Nabiul Islam +10 more
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