Results 71 to 80 of about 469,224 (385)

Frequency and Intensity of Electrical Stimulation of Human Sympathetic Ganglia Affect Heart Rate Variability and Pain Threshold

open access: yesApplied Sciences, 2019
The study relates to the selection of effective clinical treatments based on the changes associated with each electrical stimulation condition. The aim was to investigate the effects of electrical stimulation on the autonomic nervous system by evaluating
Sung-Hyoun Cho
doaj   +1 more source

The Cortico-Basal Ganglia-Cerebellar Network: Past, Present and Future Perspectives

open access: yesFrontiers in Systems Neuroscience, 2019
Much of our present understanding of the function and operation of the basal ganglia rests on models of anatomical connectivity derived from tract-tracing approaches in rodents and primates.
D. Milardi   +11 more
semanticscholar   +1 more source

Metformin promotes mitochondrial integrity through AMPK‐signaling in Leber's hereditary optic neuropathy

open access: yesFEBS Open Bio, EarlyView.
Metformin mediates mitochondrial quality control in Leber's hereditary optic neuropathy (LHON) fibroblasts carrying mtDNA mutations. At therapeutic levels, metformin activates AMPK signaling to restore mitochondrial dynamics by promoting fusion and restraining fission, while preserving mitochondrial mass, enhancing autophagy/mitophagy and biogenesis ...
Chatnapa Panusatid   +3 more
wiley   +1 more source

The role of lipid metabolism in neuronal senescence

open access: yesFEBS Open Bio, EarlyView.
Disrupted lipid metabolism, through alterations in lipid species or lipid droplet accumulation, can drive neuronal senescence. However, lipid dyshomeostasis can also occur alongside neuronal senescence, further amplifying tissue damage. Delineating how lipid‐induced senescence emerges in neurons and glial cells, and how it contributes to ageing and ...
Dikaia Tsagkari   +2 more
wiley   +1 more source

Sources of the motor and somatic sensory innervation of the trapezius muscle in the rat

open access: yesVeterinární Medicína, 2010
The study was carried out on nine sexually mature male rats of the Wistar breed weighing approximately 250 g each. Animals were anaesthetized with thiopental sodium injected intraperitoneally (30 mg/kg of body weight). The animals were then injected with
W. Sienkiewicz, A. Dudek
doaj   +1 more source

Role of basal ganglia neurocircuitry in the pathology of psychiatric disorders

open access: yesPsychiatry and Clinical Neurosciences, 2019
Over the last few decades, advances in human and animal‐based techniques have greatly enhanced our understanding of the neural mechanisms underlying psychiatric disorders.
Tom Macpherson, T. Hikida
semanticscholar   +1 more source

How Laminar Frontal Cortex and Basal Ganglia Circuits Interact to Control Planned and Reactive Saccades [PDF]

open access: yes, 2000
The basal ganglia and frontal cortex together allow animals to learn adaptive responses that acquire rewards when prepotent reflexive responses are insufficient.
Brown, Joshua   +2 more
core   +1 more source

C2MS: Dynamic Monitoring and Management of Cloud Infrastructures

open access: yes, 2013
Server clustering is a common design principle employed by many organisations who require high availability, scalability and easier management of their infrastructure.
Atkinson, Malcolm   +5 more
core   +1 more source

Visual Recovery Reflects Cortical MeCP2 Sensitivity in Rett Syndrome

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Rett syndrome (RTT) is a devastating neurodevelopmental disorder with developmental regression affecting motor, sensory, and cognitive functions. Sensory disruptions contribute to the complex behavioral and cognitive difficulties and represent an important target for therapeutic interventions.
Alex Joseph Simon   +12 more
wiley   +1 more source

Lesion Location and Functional Connections Reveal Cognitive Impairment Networks in Multiple Sclerosis

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Cognitive impairment, fatigue, and depression are common in multiple sclerosis (MS), potentially due to disruption of regional functional connectivity caused by white matter (WM) lesions. We explored whether WM lesions functionally connected to specific brain regions contribute to these MS‐related manifestations.
Alessandro Franceschini   +7 more
wiley   +1 more source

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