Tumor Glycosylation: A Main Player in the Modulation of Immune Responses. [PDF]
Cancer cells present aberrant glycosylation patterns that contribute to the evasion of antitumor immunity by triggering lectin receptors. Therefore, tumor glycosylation represents an interesting target for novel immunotherapy strategies. This review discusses the different mechanisms by which tumor‐derived glycans induce tolerogenic programs in immune ...
Rodriguez E.
europepmc +2 more sources
Integrative analysis of DNA methylation and gene expression through machine learning identifies stomach cancer diagnostic and prognostic biomarkers. [PDF]
Abstract DNA methylation is an early event in tumorigenesis. Here, by integrative analysis of DNA methylation and gene expression and utilizing machine learning approaches, we introduced potential diagnostic and prognostic methylation signatures for stomach cancer.
Hosseini M, Lotfi-Shahreza M, Nikpour P.
europepmc +2 more sources
Hallmarks of glycogene expression and glycosylation pathways in squamous and adenocarcinoma cervical cancer [PDF]
Background Dysregulation of glycogene expression in cancer can lead to aberrant glycan expression, which can promote tumorigenesis. Cervical cancer (CC) displays an increased expression of glycogenes involved in sialylation and sialylated glycans.
Patricia Martinez-Morales +8 more
doaj +3 more sources
DOENÇA AUTO-IMUNE SUGERINDO AO PET RECIDIVA DE LINFOMA HODGKIN - CONFIRMAÇÃO DA NECESSIDADE DE RE-BIOPSIAR SÍTIOS SUSPEITOS [PDF]
Relato de caso: STP, 49 anos, feminino, diagnóstico Linfoma Hodgkin Clássico, Estadio III agosto/2019. Tratamento: ABVD, 4 ciclos + Radioterapia, resposta completa ao PET CT dezembro/2019.
MP Borim
doaj +2 more sources
Confiabilidad del ganglio centinela en carcinoma de células escamosas de cavidad oral T1 / T2 N0.
El cáncer de cabeza y cuello corresponde al 3% de los cánceres en general, es el sexto más común mundialmente, afectando con más frecuencia la cavidad oral (30%). El tipo histológico más frecuente es el carcinoma de células escamosas (90%).
Alirio José Mijares Briñez +2 more
doaj +1 more source
Pan‐Cancer Analysis of B4GALNT1 as a Potential Prognostic and Immunological Biomarker
Background. Gangliosides act as important roles in tumor progression. B4GALNT1 is a key enzyme in ganglioside biosynthesis. B4GALNT1 expression is linked to tumorigenesis and the prognosis of tumor patients. Nevertheless, the role of B4GALNT1 in pan‐cancer remains unclear. Methods.
Hang Yi +6 more
wiley +1 more source
lncENSMUST00000195880‐miR‐21a‐5p‐Smad7 was constructed as an interactive regulatory network. Overexpression of lncENSMUST00000195880 inhibited miR‐21a‐5p but promoted Smad7, thereby inhibiting activation of the TGF‐β/Smad signaling pathway. Abstract Objectives Long non‐coding RNAs (lncRNAs) are critical for posttranscriptional and transcriptional ...
Wenzhao Wang +7 more
wiley +1 more source
Introducción: El cáncer de cabeza y cuello corresponde al 3% de los cánceres en general, el sexto más común mundialmente, afectando más frecuente la cavidad oral (30%). El tipo histológico más frecuente es el carcinoma de células escamosas (90%).
Alirio José Mijares Briñez +2 more
doaj +2 more sources
Turberculose ganglionar: Proposta de protocolo de atuação
Introdução: A tuberculose ganglionar (TG) é uma das formas de apresentação mais frequente de tuberculose extrapulmonar, sendo também a mais comum na área de cabeça e pescoço.
Mariana Branco Lopes +4 more
doaj +1 more source
Dor faríngea durante punção suboccipital lateral: lateral suboccipital puncture
Foi observada queixa de dor orofaríngea em cinco pacientes, conscientes e bons informantes, durante realização de punção suboccipital lateral da cisterna magna para mielo-grafia e/ou coleta de liqüido cefalorraqueano.
Sandro L. Rossitti +3 more
doaj +1 more source

