Results 11 to 20 of about 4,969 (160)

Tumor Glycosylation: A Main Player in the Modulation of Immune Responses. [PDF]

Eur J Immunol
Cancer cells present aberrant glycosylation patterns that contribute to the evasion of antitumor immunity by triggering lectin receptors. Therefore, tumor glycosylation represents an interesting target for novel immunotherapy strategies. This review discusses the different mechanisms by which tumor‐derived glycans induce tolerogenic programs in immune ...
Rodriguez E.
europepmc   +2 more sources

Integrative analysis of DNA methylation and gene expression through machine learning identifies stomach cancer diagnostic and prognostic biomarkers. [PDF]

J Cell Mol Med, 2023
Abstract DNA methylation is an early event in tumorigenesis. Here, by integrative analysis of DNA methylation and gene expression and utilizing machine learning approaches, we introduced potential diagnostic and prognostic methylation signatures for stomach cancer.
Hosseini M, Lotfi-Shahreza M, Nikpour P.
europepmc   +2 more sources

Pan-Cancer Analysis of B4GALNT1 as a Potential Prognostic and Immunological Biomarker. [PDF]

J Immunol Res, 2022
Background. Gangliosides act as important roles in tumor progression. B4GALNT1 is a key enzyme in ganglioside biosynthesis. B4GALNT1 expression is linked to tumorigenesis and the prognosis of tumor patients. Nevertheless, the role of B4GALNT1 in pan‐cancer remains unclear. Methods.
Yi H, Lin Y, Li Y, Guo Y, Yuan L, Mao Y.
europepmc   +2 more sources

Hallmarks of glycogene expression and glycosylation pathways in squamous and adenocarcinoma cervical cancer [PDF]

PeerJ, 2021
Background Dysregulation of glycogene expression in cancer can lead to aberrant glycan expression, which can promote tumorigenesis. Cervical cancer (CC) displays an increased expression of glycogenes involved in sialylation and sialylated glycans.
Patricia Martinez-Morales, Irene Morán Cruz, Lorena Roa-de la Cruz, Paola Maycotte, Juan Salvador Reyes Salinas, Victor Javier Vazquez Zamora, Claudia Teresita Gutierrez Quiroz, Alvaro Jose Montiel-Jarquin, Verónica Vallejo-Ruiz   +8 more
doaj   +3 more sources

DOENÇA AUTO-IMUNE SUGERINDO AO PET RECIDIVA DE LINFOMA HODGKIN - CONFIRMAÇÃO DA NECESSIDADE DE RE-BIOPSIAR SÍTIOS SUSPEITOS [PDF]

Hematology, Transfusion and Cell Therapy, 2021
Relato de caso: STP, 49 anos, feminino, diagnóstico Linfoma Hodgkin Clássico, Estadio III agosto/2019. Tratamento: ABVD, 4 ciclos + Radioterapia, resposta completa ao PET CT dezembro/2019.
MP Borim
doaj   +2 more sources

Confiabilidad del ganglio centinela en carcinoma de células escamosas de cavidad oral T1 / T2 N0.

Revista Científica CMDLT, 2022
El cáncer de cabeza y cuello corresponde al 3% de los cánceres en general, es el sexto más común mundialmente, afectando con más frecuencia la cavidad oral (30%). El tipo histológico más frecuente es el carcinoma de células escamosas (90%).
Alirio José Mijares Briñez, Carmen María Suárez, Alexandra Franco Yamarte   +2 more
doaj   +1 more source

Genome‐wide analysis of acute traumatic spinal cord injury‐related RNA expression profiles and uncovering of a regulatory axis in spinal fibrotic scars

Cell Proliferation, Volume 54, Issue 1, January 2021., 2021
lncENSMUST00000195880‐miR‐21a‐5p‐Smad7 was constructed as an interactive regulatory network. Overexpression of lncENSMUST00000195880 inhibited miR‐21a‐5p but promoted Smad7, thereby inhibiting activation of the TGF‐β/Smad signaling pathway. Abstract Objectives Long non‐coding RNAs (lncRNAs) are critical for posttranscriptional and transcriptional ...
Wenzhao Wang, Jun Li, Zhengdong Zhang, Huixu Ma, Qin Li, Hai Yang, Mingxin Li, Lei Liu   +7 more
wiley   +1 more source

Confiabilidad de la biopsia por ganglio centinela en el carcinoma de células escamosas de cavidad oral T1 / T2 N0 comparando los pacientes intervenidos por ganglio centinela y a los intervenidos con disección del cuello.

Revista Científica CMDLT, 2022
Introducción: El cáncer de cabeza y cuello corresponde al 3% de los cánceres en general, el sexto más común mundialmente, afectando más frecuente la cavidad oral (30%). El tipo histológico más frecuente es el carcinoma de células escamosas (90%).
Alirio José Mijares Briñez, Carmen María Suarez, Alexandra Betzabeth Franco Yamarte   +2 more
doaj   +2 more sources

Turberculose ganglionar: Proposta de protocolo de atuação

Revista Portuguesa Otorrinolaringologia e Cirurgia de Cabeça e Pescoço, 2022
Introdução: A tuberculose ganglionar (TG) é uma das formas de apresentação mais frequente de tuberculose extrapulmonar, sendo também a mais comum na área de cabeça e pescoço.
Mariana Branco Lopes, Filipa Ferreira, Cláudia Santos, Carla André, Luís Antunes   +4 more
doaj   +1 more source

A GM1b/asialo‐GM1 oligosaccharide‐binding R‐type lectin from purplish bifurcate mussels Mytilisepta virgata and its effect on MAP kinases

The FEBS Journal, Volume 287, Issue 12, Page 2612-2630, June 2020., 2020
A 15‐kDa lectin (SeviL) was isolated from the purplish bifurcate mussel, Mytilisepta virgata. SeviL binds to gangliosides and was classified as an R‐type lectin. mRNA of SeviL was expressed in gills, and this orthologue was identified in another genus Mytilus galloprovincialis from which express mytilectins.
Yuki Fujii, Marco Gerdol, Sarkar M. A. Kawsar, Imtiaj Hasan, Francesca Spazzali, Tatsusada Yoshida, Yukiko Ogawa, Sultana Rajia, Kenichi Kamata, Yasuhiro Koide, Shigeki Sugawara, Masahiro Hosono, Jeremy R. H. Tame, Hideaki Fujita, Alberto Pallavicini, Yasuhiro Ozeki   +15 more
wiley   +1 more source