Results 11 to 20 of about 4,959 (158)

Integrative analysis of DNA methylation and gene expression through machine learning identifies stomach cancer diagnostic and prognostic biomarkers. [PDF]

J Cell Mol Med, 2023
Abstract DNA methylation is an early event in tumorigenesis. Here, by integrative analysis of DNA methylation and gene expression and utilizing machine learning approaches, we introduced potential diagnostic and prognostic methylation signatures for stomach cancer.
Hosseini M, Lotfi-Shahreza M, Nikpour P.
europepmc   +2 more sources

Tumor Glycosylation: A Main Player in the Modulation of Immune Responses. [PDF]

Eur J Immunol
Cancer cells present aberrant glycosylation patterns that contribute to the evasion of antitumor immunity by triggering lectin receptors. Therefore, tumor glycosylation represents an interesting target for novel immunotherapy strategies. This review discusses the different mechanisms by which tumor‐derived glycans induce tolerogenic programs in immune ...
Rodriguez E.
europepmc   +2 more sources

Pan-Cancer Analysis of B4GALNT1 as a Potential Prognostic and Immunological Biomarker. [PDF]

J Immunol Res, 2022
Background. Gangliosides act as important roles in tumor progression. B4GALNT1 is a key enzyme in ganglioside biosynthesis. B4GALNT1 expression is linked to tumorigenesis and the prognosis of tumor patients. Nevertheless, the role of B4GALNT1 in pan‐cancer remains unclear. Methods.
Yi H, Lin Y, Li Y, Guo Y, Yuan L, Mao Y.
europepmc   +2 more sources

Genome‐wide analysis of acute traumatic spinal cord injury‐related RNA expression profiles and uncovering of a regulatory axis in spinal fibrotic scars

Cell Proliferation, Volume 54, Issue 1, January 2021., 2021
lncENSMUST00000195880‐miR‐21a‐5p‐Smad7 was constructed as an interactive regulatory network. Overexpression of lncENSMUST00000195880 inhibited miR‐21a‐5p but promoted Smad7, thereby inhibiting activation of the TGF‐β/Smad signaling pathway. Abstract Objectives Long non‐coding RNAs (lncRNAs) are critical for posttranscriptional and transcriptional ...
Wenzhao Wang, Jun Li, Zhengdong Zhang, Huixu Ma, Qin Li, Hai Yang, Mingxin Li, Lei Liu   +7 more
wiley   +1 more source

A GM1b/asialo‐GM1 oligosaccharide‐binding R‐type lectin from purplish bifurcate mussels Mytilisepta virgata and its effect on MAP kinases

The FEBS Journal, Volume 287, Issue 12, Page 2612-2630, June 2020., 2020
A 15‐kDa lectin (SeviL) was isolated from the purplish bifurcate mussel, Mytilisepta virgata. SeviL binds to gangliosides and was classified as an R‐type lectin. mRNA of SeviL was expressed in gills, and this orthologue was identified in another genus Mytilus galloprovincialis from which express mytilectins.
Yuki Fujii, Marco Gerdol, Sarkar M. A. Kawsar, Imtiaj Hasan, Francesca Spazzali, Tatsusada Yoshida, Yukiko Ogawa, Sultana Rajia, Kenichi Kamata, Yasuhiro Koide, Shigeki Sugawara, Masahiro Hosono, Jeremy R. H. Tame, Hideaki Fujita, Alberto Pallavicini, Yasuhiro Ozeki   +15 more
wiley   +1 more source

Pedro Ramón y Cajal: The Legacy of a Neurohistologist, a Medical Doctor, and a Pathologist

The Anatomical Record, Volume 303, Issue 5, Page 1189-1202, May 2020., 2020
ABSTRACT The work of Santiago Ramón y Cajal is difficult to understand without knowing the personalities of Justo, his father, and his brother Pedro. His father practically forced the two brothers to study medicine. Thanks to that, Santiago was able to combine his artistic talent with histology and wonderfully describe cerebral architecture.
Santiago Ramón y Cajal, Juan A. de Carlos   +1 more
wiley   +1 more source

Utilidad de la Tomografía por Emisión de Positrones (PET) y biopsia del ganglio centinela (BGC) en el estadiaje cervical N0 del carcinoma epidermoide orofaríngeo [PDF]

Oncología (Barcelona), 2004
INTRODUCCIÓN: con los métodos diagnósticos actuales, la determinación de metástasis cervicales ocultas (pN0) de carcinoma escamosos orofaríngeo resulta sumamente dificultoso. OBJETIVOS: el empleo de una nueva técnica diagnóstica evitará la realización innecesaria de disecciones cervicales.
Sánchez López, J. D., Valencia Laseca, E., Muros de Fuentes, M. A., Llamas Elvira, J. L., Ruiz López, J. M., Concha López, A.   +5 more
openaire   +3 more sources

Linfadenopatías generalizadas como manifestación inicial de lupus eritematoso sistémico: a propósito de un caso clínico

Revista Paraguaya de Reumatología, 2023
La presencia de linfadenopatías generalizadas se ha asociado de forma usual con lupus eritematoso sistémico (LES), sin embargo, no es usual encontrar este hallazgo como manifestación inicial de la enfermedad.
María Raad Sarabia, Gabriel Beltran Hoyos, Kewin Hernandez Pino, Jorge Acosta Buelva, Katty Chamorro Acevedo, Jorge Rico Fontalvo, Lourdes Carolina Vázquez Jiménez   +6 more
doaj   +1 more source

Paracoccidioidomicose aguda/subaguda disseminada. Primeiro caso no Rio Grande do Sul Acute/subacute disseminated paracoccidioidomycosis. First case in Rio Grande do Sul State, Brazil

Revista da Sociedade Brasileira de Medicina Tropical, 1998
É relatado o primeiro caso autóctone de paracoccidioidomicose disseminada aguda/subaguda ocorrido em criança no Rio Grande do Sul. A doença iniciou com adenomegalias superficiais generalizadas, seis meses antes da internação hospitalar. O diagnóstico foi
Soraya Malafaia Colares, Silvana Marcantônio, Simone Zambonato, Luiz Carlos Severo   +3 more
doaj   +1 more source

Distribución Topográfica de Metástasis de Origen Desconocido

Oncología, 2019
Introducción: La metástasis de origen desconocido es una entidad clínica relativamente común, que representa del 5% de todos los cánceres invasivos. La búsqueda del origen primario puede resultar desafiante por un patrón atípico metastásico, no obstante
John Ortega Cedeño, Evelyn Solórzano Pérez   +1 more
doaj   +1 more source