Reduced neurosteroid potentiation of GABAA receptors in epilepsy and depolarized hippocampal neurons [PDF]
, 2020 OBJECTIVE: Neurosteroids regulate neuronal excitability by potentiating γ-aminobutyric acid type-A receptors (GABARs). In animal models of temporal lobe epilepsy, the neurosteroid sensitivity of GABARs is diminished and GABAR subunit composition is ...
Jansen, Laura A +3 more
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Machine Learning Decision Tree Models for Differentiation of Posterior Fossa Tumors Using Diffusion Histogram Analysis and Structural MRI Findings. [PDF]
, 2020 We applied machine learning algorithms for differentiation of posterior fossa tumors using apparent diffusion coefficient (ADC) histogram analysis and structural MRI findings.
Aboian, Mariam +3 more
core +1 more source
Pediatric intracerebral anaplastic ganglioglioma : A Case Report
Nepal Journal of Neuroscience, 2019 Anaplastic ganglioglioma (AGG) is an extremely rare aggressive, epileptogenic braintumor. It is considered to be WHO grade III variant of ganglioglioma. Due to non-specific clinical manifestations and radiographic features, preoperative diagnosis of AGG ...
Dipendra Kumar Shrestha +3 more
doaj +1 more source
Duplications of KIAA1549 and BRAF screening by Droplet Digital PCR from formalin-fixed paraffin-embedded DNA is an accurate alternative for KIAA1549-BRAF fusion detection in pilocytic astrocytomas [PDF]
, 2018 Pilocytic astrocytomas represent the most common glioma subtype in young patients and account for 5.4% of all gliomas. They are characterized by alterations in the RAS–MAP kinase pathway, the most frequent being a tandem duplication on chromosome 7q34 ...
Appay, Romain +13 more
core +3 more sources
Neurology International, 2021 Central precocious puberty (CPP) is a condition that causes early gonadotropin-dependent sexual development; CPP is idiopathic in girls in most cases, whereas more than 50% of boys have an identifiable etiology.
Roberta Rana +11 more
doaj +1 more source
Intramedullary gangliogliomas: histopathologic and molecular features of 25 cases [PDF]
, 2016 Gangliogliomas are uncommon glioneuronal tumors, which usually arise in the cerebral hemispheres and occasionally in the brain stem. Gangliogliomas occurring in the spinal cord are extremely rare. In this study, we analyzed the clinical, histopathologic,
ANTONELLI, MANILA +7 more
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Purely Cystic Desmoplastic Ganglioglioma: An Incidental Finding in a Giant Cyst
Indian Journal of Neurosurgery, 2017 Desmoplastic infantile ganglioglioma (DIG) is a rare supratentorial brain tumor occurring mostly before the age of 2 years. It has a good prognosis and total excision of the tumor is curative, necessitating no further treatment.
Sumit Bansal +3 more
doaj +1 more source
Concurrent MEK targeted therapy prevents MAPK pathway reactivation during BRAFV600E targeted inhibition in a novel syngeneic murine glioma model. [PDF]
, 2016 Inhibitors of BRAFV600E kinase are currently under investigations in preclinical and clinical studies involving BRAFV600E glioma. Studies demonstrated clinical response to such individualized therapy in the majority of patients whereas in some patients ...
Berger, Mitchel S +12 more
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Evolução maligna de um ganglioglioma: relato de caso [PDF]
Arquivos de Neuro-Psiquiatria, 1998 Relatamos o caso de um paciente de oito anos de idade, com quadro clínico de cefaléia, náuseas e vômitos. A angiografia cerebral mostrava massa frontal não vascularizada.
JOÃO FLÁVIO MATTOS ARAÚJO +3 more
doaj +1 more source
Ganglioglioma da região da pineal: relato de caso Ganglioglioma of the pineal region: case report
Arquivos de Neuro-Psiquiatria, 2001 Os gangliogliomas são neoplasias mistas, compostas de elementos gliais e neuronais, extremamente raros na região da glândula pineal. Na presente revisão da literatura foram encontrados oito casos publicados.
Walter José Fagundes-Pereyra +3 more
doaj +1 more source