Results 41 to 50 of about 4,691 (173)

Research progress on the use of the optical coherence tomography system for the diagnosis and treatment of central nervous system tumors

open access: yesIbrain, Volume 11, Issue 1, Page 3-18, Spring 2025.
With the advantages of high‐resolution imaging, efficient image acquisition, intraoperative real‐time detection, and radiation‐free and noninvasive characteristics, optical coherence tomography (OCT) provides accurate diagnosis and effective intraoperative guidance for the minimally invasive diagnosis and treatment of central nervous system (CNS ...
Jiuhong Li   +10 more
wiley   +1 more source

The Efficacy of Pharmacotherapy Intervention on Anthropometric Outcomes in Survivors of Childhood Brain Tumors: An Updated Systematic Review and Meta‐Analysis

open access: yesObesity Reviews, EarlyView.
ABSTRACT Introduction Many survivors of childhood brain tumors face long‐term adverse health outcomes like obesity. Uncertainties surround the effect of interventions to manage obesity‐related outcomes in survivors of childhood brain tumors. The goal of this updated systematic review and meta‐analysis was to provide the best estimate of the treatment ...
David Hart   +11 more
wiley   +1 more source

HierAnom‐Path: Zero‐Shot Rare Cancer Detection in Histopathology via Hierarchical Foundation Model Adaptation

open access: yesComputational and Systems Oncology, Volume 6, Issue 1, December 2026.
ABSTRACT Rare cancers collectively represent 20%–25% of all malignancies yet yield fewer than 50 annotated whole‐slide images (WSIs) per subtype in publicly available archives, rendering supervised deep learning inapplicable. We present HierAnom‐Path, to the best of our knowledge, the first framework for zero‐shot rare cancer anomaly detection in ...
Noora Saleem Jumaah   +5 more
wiley   +1 more source

Mapping the Phenotypic Spectrum of Occipital Lobe Epilepsy: A SEEG‐Defined Network Classification

open access: yesCNS Neuroscience &Therapeutics, Volume 32, Issue 8, August 2026.
This SEEG‐based study identifies four propagation patterns in occipital lobe epilepsy (restricted, ventral–limbic, dorsal/DMN–limbic, and lateral TPOJ) linked to five clinical phenotypes. Seizure semiology is shaped by pathway‐selective propagation rather than the onset zone alone, providing a network‐based framework for personalized surgical planning.
Changquan Wang   +5 more
wiley   +1 more source

Characteristics and long‐term outcomes of children with confirmed focal cortical dysplasia type 1 after epilepsy surgery: A population‐based study

open access: yesEpilepsia Open, Volume 11, Issue 4, Page 1314-1328, August 2026.
Abstract Objective Focal cortical dysplasia type 1 (FCD1) is a rare and heterogeneous cause of drug‐resistant epilepsy (DRE) in children. Its clinical characteristics remain poorly understood, and surgical outcomes may be less favorable than in FCD2. We conducted a population‐based study to characterize the clinical presentation and long‐term seizure ...
Vincent Zheng   +9 more
wiley   +1 more source

Ganglioglioma and gangliocytoma: a review for pathologists [PDF]

open access: yesJournal of Pathology and Translational Medicine
Ganglioglioma and gangliocytoma are rare, predominantly low-grade neuroepithelial tumors that commonly present with epilepsy in children and young adults. Advances in molecular profiling have improved understanding of their pathogenesis, highlighting key
Gianfranco E. Umeres-Francia   +3 more
doaj   +1 more source

Ganglioglioma surgery associated with postoperative status epilepticus: a case report

open access: yesActa Epileptologica, 2022
Background Gangliogliomas are brain tumors associated with drug-resistant focal epilepsy. In most cases, seizures improve after surgical treatment. It is still not concluded to what extent the lesion itself or the perilesional area contributes to the ...
Irena Grubor   +2 more
doaj   +1 more source

Assessing Cognitive Functioning in Children With Brain Tumors: Interaction of Neighborhood Social Determinants of Health and Neurological Risk

open access: yesPediatric Blood &Cancer, Volume 73, Issue 7, July 2026.
ABSTRACT Background This study investigated how neighborhood‐level social determinants of health (SDOH), including redlining and neurological risk, interact to influence cognitive outcomes in children treated for brain tumors (CTBT). Methods A retrospective chart review of 161 CTBT aged 5–17 was conducted.
Alannah R. Srsich   +5 more
wiley   +1 more source

Tumor‐type–specific expression of TTF‐1 in primary central nervous system tumors classified by the 2021 WHO criteria

open access: yesThe Journal of Pathology: Clinical Research, Volume 12, Issue 4, July 2026.
Abstract Thyroid transcription factor‐1 (TTF‐1) is a widely used immunohistochemical marker for tumors of thyroid and pulmonary origin; however, its expression profile and diagnostic relevance in primary central nervous system (CNS) tumors remain incompletely characterized, particularly following the revisions in the 2021 WHO Classification of CNS ...
Lu Xu   +8 more
wiley   +1 more source

Case Series of Intracranial Central Primitive Neuroectodermal Tumor in Two Adults Treated With Craniospinal Irradiation

open access: yesClinical Case Reports, Volume 14, Issue 7, July 2026.
ABSTRACT Ewing sarcoma and primitive neuroectodermal tumors share histological and genetic characteristics, yet differ in management, with EWSR1 rearrangement being the key distinguishing factor. Such intracranial tumors lacking this rearrangement are rare in adults.
Shubham Dokania   +7 more
wiley   +1 more source

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