Results 51 to 60 of about 7,310 (199)

Research progress on the use of the optical coherence tomography system for the diagnosis and treatment of central nervous system tumors

Ibrain, Volume 11, Issue 1, Page 3-18, Spring 2025.
With the advantages of high‐resolution imaging, efficient image acquisition, intraoperative real‐time detection, and radiation‐free and noninvasive characteristics, optical coherence tomography (OCT) provides accurate diagnosis and effective intraoperative guidance for the minimally invasive diagnosis and treatment of central nervous system (CNS ...
Jiuhong Li, Ziba Ayi, Gonggong Lu, Haibo Rao, Feilong Yang, Jing Li, Jiachen Sun, Junlin Lu, Xulin Hu, Si Zhang, Xuhui Hui   +10 more
wiley   +1 more source

Fish oil (n-3 fatty acids) in drug resistant epilepsy: a randomised placebo-controlled crossover study. [PDF]

, 2014
Backgroundn-3 fatty acids inhibit neuronal excitability and reduce seizures in animal models. High-dose fish oil has been explored in two randomised trials in drug resistant epilepsy with negative results.
DeGiorgio, Christopher M, Gornbein, Jeffrey, Harper, Ronald, Meymandi, Sheba, Miller, Patrick R, Schrader, Lara, Soss, Jason   +6 more
core   +1 more source

Immunohistochemistry as a tool for identifying EGFR amplification in CNS tumors

Brain Pathology, EarlyView.
EGFR gene amplification constitutes a diagnostic hallmark for glioblastoma, IDH‐wildtype (GB, IDH‐WT). Herein, we demonstrated that EGFR IHC is a highly specific and sensitive biomarker for identifying EGFR amplification and should be part of the neuropathologist's routine panel of antibodies.
Arnault Tauziède‐Espariat, Mary Bah, Farah Sassi, Noémie Pucelle, Charlotte Berthaud, Marion Mandoula, Zeina Dababou, Noah Carnes, Leïla Brissez, Lauren Hasty, Euphrasie Servant, Alice Métais, Pascale Varlet   +12 more
wiley   +1 more source

Studies with the Golgi method in central gangliogliomas and dysplastic gangliocytoma of the cerebellum (Lhermitte-Duclos disease) [PDF]

, 2017
The rapid Golgi method, combined with current optical and electronmicroscopica1 techniques, was used in three central gangliogliomas and in one dysplastic gangliocytoma of the cerebellum to study the morphology of ganglionic cells.
Bella, R., Conesa Bertrán, Gerardo, Ferrer, Isidro (Ferrer Abizanda), Guionnet, N., Isamat de la Riva, F. (Fabián), Martí, E., Serrano Piñol, M. Teresa, Towse, J.   +7 more
core  

Profiling Critical Cancer Gene Mutations in Clinical Tumor Samples [PDF]

, 2012
Background: Detection of critical cancer gene mutations in clinical tumor specimens may predict patient outcomes and inform treatment options; however, high-throughput mutation profiling remains underdeveloped as a diagnostic approach.
Baker, Alissa C., Bass, Adam Joel, Campbell, Catarina D., Chan, Jennifer Ang, Corso, Gianni, Davis, Matthew J, Emery, Caroline Margaret, Fiorentino, Michelangelo, Fletcher, Jonathan A., Garraway, Levi Alexander, Goff, Deborah J., Hahn, William C., Hanna, Megan, Hatton, Charles, Jones, Chris, Kehoe, Sarah M., Kieran, Mark W., Ligon, Keith Lloyd, Luongo, Lauren, MacConaill, Laura Eleanor, Meyerson, Matthew Langer, Mondal, Chandrani, Niu, Lili, Philips, Juliet, Polyak, Kornelia, Roviello, Franco, Rubin, Mark A., Santagata, Sandro, Shivdasani, Ramesh Arjun, Stiles, Charles Dean, Wang, Yufang, Yao, Keluo   +31 more
core   +2 more sources

Whole-genome sequencing identifies genetic alterations in pediatric low-grade gliomas [PDF]

, 2013
The most common pediatric brain tumors are low-grade gliomas (LGGs). We used whole-genome sequencing to identify multiple new genetic alterations involving BRAF, RAF1, FGFR1, MYB, MYBL1 and genes with histone-related functions, including H3F3A and ATRX ...
A Gajjar, A Korshunov, A Lin, A McPherson, A Peraud, A von Deimling, AJ Sievert, AK Gnekow, B Tang, C Bettegowda, CG Mullighan, CG Mullighan, D Dias-Santagata, D Singh, D Sturm, DA Persons, DN Louis, DN Louis, DT Jones, DT Jones, DT Jones, DW Ellison, DW Parsons, E Bouffet, F Li, G Schindler, G Wu, GT Armstrong, H Cin, H Li, H Ohgaki, H Ohgaki, H Ohgaki, H Yan, I Qaddoumi, IF Pollack, IF Pollack, J Jonkers, J Schwartzentruber, J Wang, J Zhang, J Zhang, J Zhang, JE DeClue, JH Wisoff, JR Downing, KT Flaherty, M Katoh, M Ren, M Wang, MJ Ciesielski, MJ Riemenschneider, ML Bajenaru, MN Edmonson, N Turner, N Turner, ND Dees, PG Fisher, PJ Stephens, PK Duffner, R Endersby, R Listernick, R Listernick, RG Tatevossian, RG Tatevossian, RS Arora, S Pfister, S Yip, T Forshew, T Stokland, TE Merchant, V Rand, W Müller, WM Lin, Y Okamoto   +74 more
core   +1 more source

Double dissociation between conduction aphasia and conduction agraphia supports a ventro‐dorsal partition of the left arcuate fasciculus

Journal of Neuropsychology, EarlyView.
Abstract We identified in two awake surgery cases a postoperative double dissociation between phonological and graphemic output buffer deficits. Using lesion‐symptom mapping from ischaemic mini‐strokes and preoperative tractography, we demonstrated that the phonological (resp. graphemic) disorder fitted with ventral (resp.
Valéry Mandonnet, Isabelle Poisson, Francine Chassoux, Bertrand Devaux, Sébastien Froelich, Emmanuel Mandonnet   +5 more
wiley   +1 more source

Ganglioglioma surgery associated with postoperative status epilepticus: a case report

Acta Epileptologica, 2022
Background Gangliogliomas are brain tumors associated with drug-resistant focal epilepsy. In most cases, seizures improve after surgical treatment. It is still not concluded to what extent the lesion itself or the perilesional area contributes to the ...
Irena Grubor, Maria Compagno Strandberg, Johan Bengzon   +2 more
doaj   +1 more source

Cerebellar Cystic Metastasis—An Unusual Presentation of Prostate Adenocarcinoma Dissemination: A Case Report

Clinical Case Reports, Volume 14, Issue 4, April 2026.
ABSTRACT Although prostate cancer is among the most common malignant tumors in men, brain metastases from prostatic cancer are infrequent. Brain dissemination is especially rare with the most frequent histological type of prostatic adenocarcinoma. We present a case of a cystic‐hemorrhagic cerebellar metastasis with a solid enhancing component in a ...
Mia Smoljan Basuga, Mirjana Flegarić‐Bradić, Antonio Klemenčić, Matea Prenc, Tamara Rihtar, Dijana Zadravec   +5 more
wiley   +1 more source

Prolonged Response Induced by Single Agent Vemurafenib in a BRAF V600E Spinal Ganglioglioma: A Case Report and Review of the Literature

Frontiers in Oncology, 2019
Spinal ganglioglioma is a rare low-grade, slow-growing tumor of the central nervous system affecting mostly children and young adults. After surgery, some patients show tumor recurrence and/or malignant transformation.
Louis Garnier, François Ducray, Clotilde Verlut, Marcella-Ionela Mihai, Françoise Cattin, Antoine Petit, Elsa Curtit   +6 more
doaj   +1 more source