Results 161 to 170 of about 441,395 (420)

How does the inner retinal network shape the ganglion cells receptive field : a computational study [PDF]

open access: yesarXiv
We consider a model of basic inner retinal connectivity where bipolar and amacrine cells interconnect, and both cell types project onto ganglion cells, modulating their response output to the brain visual areas. We derive an analytical formula for the spatio-temporal response of retinal ganglion cells to stimuli taking into account the effects of ...
arxiv  

Single Administration of AAV‐mAtp6v1b2 Gene Therapy Rescues Hearing and Vestibular Disorders Caused by Atp6v1b2‐Induced Lysosomal Dysfunction in Hair Cells

open access: yesAdvanced Science, EarlyView.
Wei et al. establish a hair cell‐specific conditional knockout mouse model (Atp6v1b2fl/fl;Atoh1Cre/+), and demonstrate the importance of Atp6v1b2 for hair cell through maintaining the survival of lysosomes. A single administration of AAV‐ie‐Eh3‐mAtp6v1b2 through scala media at P0‐P2 realizes function compensation and restores hearing and balance ...
Gege Wei   +15 more
wiley   +1 more source

Revealing structure components of the retina by deep learning networks [PDF]

open access: yesarXiv, 2017
Deep convolutional neural networks (CNNs) have demonstrated impressive performance on visual object classification tasks. In addition, it is a useful model for predication of neuronal responses recorded in visual system. However, there is still no clear understanding of what CNNs learn in terms of visual neuronal circuits. Visualizing CNN's features to
arxiv  

GDC: Integration of Multi‐Omic and Phenotypic Resources to Unravel the Genetic Pathogenesis of Hearing Loss

open access: yesAdvanced Science, EarlyView.
Overview of the Genetic Deafness Commons (GDC), integrating data from the Chinese Deafness Genetics Consortium (CDGC) and 51 public databases. The GDC provides tools for variant search, functional predictions, and gene‐disease visualization, offering insights into 201 hearing loss genes and facilitating novel gene discovery and clinical applications ...
Hui Cheng   +11 more
wiley   +1 more source

Consequences and Mechanisms of Noise‐Induced Cochlear Synaptopathy and Hidden Hearing Loss, With Focuses on Signal Perception in Noise and Temporal Processing

open access: yesAdvanced Science, EarlyView.
Noise‐induced synaptopathy (NIS) is largely reversible due to self‐repair. NIS and noise‐induced hidden hearing loss are two concepts with similarities and differences. The major hearing deficits in NIHHL are temporal processing disorders. The translation of animal data in NIS studies to humans is hindered by many factors.
Hui Wang, Steven J Aiken, Jian Wang
wiley   +1 more source

Non-identical presentations of Intra-Articular Anterior Cruciate Ligament Ganglion Cysts: A report of two cases and review of literature

open access: yesJournal of the Bulgarian Orthopaedics and Trauma Association
An uncommon cystic, tumor-like lesion of uncertain origin, an anterior cruciate ligament ganglion is encircled by dense connective tissue that is filled with a gelatinous fluid. Ganglion cysts and ACL mucoid degeneration may coexist.
Samir Dwidmuthe   +2 more
doaj   +1 more source

Predicting synchronous firing of large neural populations from sequential recordings [PDF]

open access: yesarXiv, 2019
A major goal in neuroscience is to understand how populations of neurons code for stimuli or actions. While the number of neurons that can be recorded simultaneously is increasing at a fast pace, in most cases these recordings cannot access a complete population.
arxiv  

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