Results 261 to 270 of about 571,997 (336)

A Review of the Mechanisms of Action of the Herbal Medicine, STW 5‐II, Underlying Its Efficacy in Disorders of Gut–Brain Interaction

open access: yesNeurogastroenterology &Motility, Volume 38, Issue 1, January 2026.
The pathophysiology of functional dyspepsia and irritable bowel syndrome includes altered motility, secretion, sensitivity to sensory signals, impaired epithelial barrier function, inflammation, and gut dysbiosis. The phytomedicine, STW 5‐II, represents a multi‐targeted approach, addressing these pathophysiologies.
Anita Annaházi   +6 more
wiley   +1 more source

Perlecan, CollagenXVIII, and Agrin Expression in Normo‐, Hypo‐, and Aganglionic Segments in Hirschsprung's Disease

open access: yesNeurogastroenterology &Motility, Volume 38, Issue 1, January 2026.
The secretory heparan sulphate proteoglycans perlecan, agrin, collagen18A1 are expressed in the periganglionic sheath of enteric ganglia in resectates of Hirschsprung's disease patients and non‐Hirschsprung controls. ABSTRACT Background Secretory heparan sulphate proteoglycans (HSPGs) interact with various morphogens, growth factors, and signaling ...
Nico van den Beld   +6 more
wiley   +1 more source

Mycotic Sphenopalatine Sinusitis With Concurrent Compression of the Optic Nerves and Chiasm and Severe Visual Impairment in A Horse

open access: yesVeterinary Ophthalmology, Volume 29, Issue 1, January 2026.
ABSTRACT A 15‐year‐old Swiss Warmblood gelding was presented to the ophthalmology service of Zurich University due to severe visual impairment. Ophthalmic and neurologic examinations were performed, raising suspicion of post‐retinal blindness. Standing contrast computed tomography (CT) of the head revealed a partially calcified, soft tissue attenuating
Niklas Holz   +4 more
wiley   +1 more source

Targeting ecto‐5′‐nucleotidase (CD73) and cAMP alleviates carotid body hyperactivity and reduces blood pressure in chronically hypoxic rats

open access: yesThe Journal of Physiology, Volume 604, Issue 1, Page 626-652, 1 January 2026.
Abstract figure legend CD73 promotes carotid body hyperactivity in chronically hypoxic animals. Exposure to chronic hypoxia (CH) (FiO2 of 12% for 10 days) increases the proportion of CD73+TH+ cells in the carotid body and induces basal chemoafferent hyperactivity.
Demitris Nathanael   +4 more
wiley   +1 more source

The P2X7 Receptor and Its Relation to Neglected Tropical Diseases: Focusing on Chagas Disease

open access: yesJournal of Tropical Medicine, Volume 2026, Issue 1, 2026.
Chagas disease, caused by Trypanosoma cruzi, is a neglected tropical disease (NTD) that can lead to severe cardiac complications, including chronic Chagas cardiomyopathy. While NTDs are caused by a variety of pathogens—such as protozoa, bacteria, viruses, and helminths, Chagas disease remains underexplored, particularly regarding host immune responses.
Caroline de Souza Ferreira Pereira   +2 more
wiley   +1 more source

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