Results 131 to 140 of about 28,808 (171)

Intra-Articular Administration of Ganglioside Sugars Protects Cartilage from Progressive Degeneration in an Instability OA Rabbit Model. [PDF]

Cartilage
Hamasaki M, Onodera T, Furukawa J, Todoh M, Sakai Y, Ebata T, Terkawi MA, Homan K, Iwasaki N.   +8 more
europepmc   +1 more source

GD2 in Breast Cancer: A Potential Biomarker and Therapeutic Target. [PDF]

Cancer Genomics Proteomics
Mokbel K.
europepmc   +1 more source

Post-COVID-19 Guillain-Barré Syndrome with GM1 and GD1b Antibodies: A Case Study and Literature Review. [PDF]

Am J Case Rep
Thiriveedi M, Sto Domingo FG, Longley S, Patel S, Baddam S, Chimakurthy A.   +5 more
europepmc   +1 more source

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Gangliosides and hearing

Biochimica et Biophysica Acta (BBA) - General Subjects, 2017
Severe auditory impairment observed in GM3 synthase-deficient mice and humans indicates that glycosphingolipids, especially sialic-acid containing gangliosides, are indispensable for hearing. Gangliosides associate with glycoproteins to form membrane microdomains, the composition of which plays a special role in maintaining the structural and ...
Shinji Go, Shinji Go, Kevin A. Strauss, Misato Yoshikawa, Misato Yoshikawa, Jin-ichi Inokuchi   +5 more
openaire   +3 more sources

Gangliosides of Melanoma

The Journal of Dermatology, 1992
AbstractThe relationships between the ganglioside composition of melanomas and their biologic behavior were investigated. (1) The amount of GM2 and/or GD2 in melanoma cells injected into nude mice correlated with the tumor growth rate. (2) GD2 content of melanoma cell lines correlated with sensitivity to radiation and vincristine. (3) GM2 expression of
Tetsuya Tsuchida, Yasumasa Ishibashi
openaire   +3 more sources

Gangliosides in Neuroblastomas

Neurochemical Pathology, 1988
Neuroblastomas from children presenting with tumors at various ages and different primary sites (abdominal, adrenals, pelvic, and thoracic) were studied. Analysis of the ganglioside patterns of 53 tumors indicated that patients who were either disease positive 2 yr following surgery or dead of disease, had significantly (p less than 0.005) less GT1b ...
Cara Lynne Schengrund, Stephen J. Shochat   +1 more
openaire   +3 more sources

Gangliosides and parkinsonism

Neurology, 1993
The protective effect of GM1 ganglioside against nerve cell death induced by 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP) was analyzed in monkey mesencephalon. Administration of GM1 before and during MPTP treatment improved motor performances compared with MPTP-treated animals that received saline rather than GM1.
E. C. Hirsch, Isabel Pérez-Otaño, Maria Herrero, Yves Agid, J. Del Río, Jose A. Obeso, F. Javoy-Agid, A. Kastner, Maria-Rosario Luquin   +8 more
openaire   +3 more sources

Gangliosides and atherosclerosis

Lipids, 1994
AbstractThe ganglioside levels in atherosclerotic lesions of human aorta are considerably higher than those in unaffected areas of aorta, and atherosclerotic patients frequently have increased concentrations of serum gangliosides. The present review summarizes recent findings that suggest the possible involvement of aortic gangliosides in platelet ...
N. V. Prokazova, L. D. Bergelson
openaire   +3 more sources

Gangliosides and Tumors

2018
Tumor-associated gangliosides play important roles in regulation of signal transduction induced by growth-factor receptors including EGFR, FGFR, HGF and PDGFR in a specific microdomain called glycosynapse in the cancer cell membranes, and in interaction with glycan recognition molecules involved in cell adhesion and immune regulation including ...
Chia-Chun Chao, Reiji Kannagi, Bi-He Cai, Hsiang-Chi Huang, Keiichiro Sakuma   +4 more
openaire   +3 more sources