Results 111 to 120 of about 53,157 (259)

Porcine intestinal glycosphingolipids recognized by F6-fimbriated enterotoxigenic Escherichia coli [PDF]

, 2014
One important virulence factor of enterotoxigenic Escherichia coli is their ability to adhere via fimbrial adhesins to specific receptors located on the intestinal mucosa. Here, the potential glycosphingolipid receptors of enterotoxigenic F6-fimbriated E.
Benktander, John, Coddens, Annelies, Cox, Eric, Johansson, Miralda Madar, Teneberg, Susann   +4 more
core   +2 more sources

Dietary gangliosides rescue GM3 synthase deficiency outcomes in mice accompanied by neurogenesis in the hippocampus

Frontiers in Neuroscience
Ganglioside GM3 synthase is a key enzyme involved in the biosynthesis of gangliosides. GM3 synthase deficiency (GM3SD) causes an absence of GM3 and all downstream biosynthetic derivatives, including all the a-, b-, c-series gangliosides, commonly found ...
Jin-ichi Inokuchi, Jin-ichi Inokuchi, Shinji Go, Akemi Suzuki, Osamu Nakagawasai, Takayo Odaira-Satoh, Lucas Veillon, Takahiro Nitta, Paul McJarrow, Hirotaka Kanoh, Kei-ichiro Inamori, Koichi Tan-No, Michael Collett   +12 more
doaj   +1 more source

Gangliosides enhance M2-polarized macrophage elongation induced by IL-4 and IL-13 [PDF]

Kosin Medical Journal
Background Macrophage polarization plays a crucial role in the immune response, and gangliosides regulate macrophage function. In this study, we investigated the role of gangliosides in modulating macrophage morphology and function in response to M2 ...
Snehal Chandrakant Meshram, Hee-Jin Choi, Minkyoung Cho, Jaewon Shim, Ki-Tae Ha, Sung-Jin Bae   +5 more
doaj   +1 more source

Production of anti-GM3, anti-GM1, and anti-GD1A antibodies by non-lymphoid cells, tissues, and organs [PDF]

Pharmacia
Gangliosides are acidic glycosphingolipids localized mainly on the outer membrane layer of the membranous cell structures. These molecules participate in important mechanisms at molecular, cellular, tissue, organ, and organism levels.
Iskra Sainova, Vera Kolyovska, Desislava Drenska, Dimitar Maslarov, Andrey Petrov, Dimitrina Dimitrova-Dikanarova, Tzvetanka Markova   +6 more
doaj   +3 more sources

Imaging Mass Spectrometry Detection of Gangliosides Species in the Mouse Brain following Transient Focal Cerebral Ischemia and Long-Term Recovery

PLoS ONE, 2011
Gangliosides, a member of the glycosphingolipid family, are heterogeneously expressed in biological membranes and are particularly enriched within the central nervous system.
S. Whitehead, Kenneth H. N. Chan, Sandhya Gangaraju, Jacqueline Slinn, Jianjun Li, S. Hou   +5 more
semanticscholar   +1 more source

Simple Model of the Transduction of Cell-Penetrating Peptides

, 2010
Cell-penetrating peptides (CPPs) such as HIV's trans-activating transcriptional activator (TAT) and polyarginine rapidly pass through the plasma membranes of mammalian cells by an unknown mechanism called transduction.
Andrews, Bevers, Chen, Datta, Dom, Duchardt, Fischer, Frankel, Grandmaison, Green, Haase, Harbour, Herce, Hosotani, Jiang, K. Cahill, Kuge, Lipinski, Mai, Melikov, Mendoza, O'Shaughnessy, Parsegian, Prochiantz, Rostovtseva, Rothbard, Rothbard, Saito, Snyder, Snyder, Stone, Tang, Tünnemann, Tünnemann, Tünnemann, Tyagi, Voelker, Wadia, Willam, Zhou, Ziegler   +40 more
core   +1 more source

NGcGM3 Ganglioside: A Privileged Target for Cancer Vaccines

Clinical and Developmental Immunology, 2010
Active specific immunotherapy is a promising field in cancer research. N-glycolyl (NGc) gangliosides, and particularly NGcGM3, have received attention as a privileged target for cancer therapy.
Luis E. Fernandez, Mariano R. Gabri, Marcelo D. Guthmann, Roberto E. Gomez, Silvia Gold, Leonardo Fainboim, Daniel E. Gomez, Daniel F. Alonso   +7 more
doaj   +1 more source

Ganglioside Metabolism in a Transgenic Mouse Model of Alzheimer's Disease: Expression of Chol-1α Antigens in the Brain

ASN Neuro, 2010
The accumulation of Aβ (amyloid β-protein) is one of the major pathological hallmarks in AD (Alzheimer's disease). Gangliosides, sialic acid-containing glycosphingolipids enriched in the nervous system and frequently used as biomarkers associated with ...
Toshio Ariga, Makoto Yanagisawa, Chandramohan Wakade, Susumu Ando, Jerry J Buccafusco, Michael P McDonald, Robert K Yu   +6 more
doaj   +1 more source

An Optimized Liquid Chromatography–Mass Spectrometry Method for Ganglioside Analysis in Cell Lines

Cells
Gangliosides are glycosphingolipids composed of a sialylated glycan head group and a ceramide backbone. These anionic lipids form lipid rafts and play crucial roles in regulating various proteins involved in signal transduction, adhesion, and cell–cell ...
Akeem Sanni, Andrew I. Bennett, Yifan Huang, Isabella Gidi, Moyinoluwa Adeniyi, Judith Nwaiwu, Min H. Kang, Michelle E. Keyel, ChongFeng Gao, C. Patrick Reynolds, Brian Haab, Yehia Mechref   +11 more
doaj   +1 more source

Temperature-Induced Seasonal Dynamics of Brain Gangliosides in Rainbow Trout (Oncorhynchus mykiss Walbaum) and Common Carp (Cyprinus carpio L.)

Life
This study aimed to determine the expression and distribution of gangliosides in specific regions of the brains of rainbow trout (Oncorhynchus mykiss Walbaum) and common carp (Cyprinus carpio L.) with regard to seasonal temperature changes.
Valentina Pavić, Barbara Viljetić, Senka Blažetić, Irena Labak, Elizabeta Has-Schön, Marija Heffer   +5 more
doaj   +1 more source