Results 111 to 120 of about 20,173 (228)
301-312This review discusses the immunology of gangliosides from the perspective of tumor, neuronal and general immunology. Antiganglioside antibodies in human sera are invariably IgM and are found in healthy individuals. Their titers decline with age.
Nishimoto, Kevin +5 more
core
Influence of Brain Gangliosides on the Formation and Properties of Supported Lipid Bilayers
This is a comprehensive study of the effects of the four major brain gangliosides (GM1, GD1b, GD1a, and GT1b) on the adsorption and rupture of phospholipid vesicles on SiO2 surfaces for the formation of supported lipid bilayer (SLB) membranes.
Luke, Jordan +4 more
core +1 more source
Cytosolic gangliosides: occurrence in calf brain as ganglioside--protein complexes
Calf brain was treated in order to prepare separately the cytosol from neuronal bodies and glial cells, and the cytosol from nerve endings. The first cytosol contained 29 μg of ganglioside bound sialic acid/g fresh tissue, the latter 3.1 μg.
S. Marchesini +3 more
core +1 more source
Objective To observe the clinical therapeutic effect of acupoint injection of medicine in the treatment of patients with acute cerebral ischemia stroke(ACIS).Methods Ninety ACIS patients were randomized into control,Cobalamin and Gangliosides groups(n ...
ZHAO Lei +4 more
doaj
Binding of interleukin 2 to gangliosides
Exogenous gangliosides inhibit interleukin 2 (IL2)-dependent growth of a T cell line, AKIL-1.E8. IL2 activity is retained by columns of ganglioside covalently linked to poly(L-lysine)-agarose and is not eluted with ethylene glycol but is completely ...
Gabriella Caldini +9 more
core +1 more source
A monoclonal antibody to human macrophage gangliosides inhibits macrophage migration
Gangliosides have diverse immunoregulatory properties. The gangliosides endogenous to macrophages may have immunoregulatory properties that distinguish them from other gangliosides.
Melissa A Patterson +3 more
core +1 more source
NGcGM3 Ganglioside: A Privileged Target for Cancer Vaccines
Active specific immunotherapy is a promising field in cancer research. N-glycolyl (NGc) gangliosides, and particularly NGcGM3, have received attention as a privileged target for cancer therapy.
Luis E. Fernandez +7 more
doaj +1 more source
The accumulation of Aβ (amyloid β-protein) is one of the major pathological hallmarks in AD (Alzheimer's disease). Gangliosides, sialic acid-containing glycosphingolipids enriched in the nervous system and frequently used as biomarkers associated with ...
Toshio Ariga +6 more
doaj +1 more source
Scheme of biosynthetic pathways for major nervous system gangliosides.
Blockades in ganglioside biosynthesis in knockout mice are indicated by solid red lines. GM2/GD2-synthase knockout mice (B4galnt1-null) mice do not express any complex gangliosides, including GM1, GD1a, GD1b or GT1b, and express only simple gangliosides ...
Tong Gao (341025) +6 more
core +1 more source
Serum gangliosides in patients with brain tumors
In order to determine possible differences in serum gangliosides content and composition before and after surgical removal of tumor, gangliosides isolated from preoperative and postoperative sera of patients with brain tumors were analyzed. Serum samples
Kalanj Bognar, Svjetlana +5 more
core

