Results 111 to 120 of about 20,173 (228)

Immunology of gangliosides

open access: yes, 2000
301-312This review discusses the immunology of gangliosides from the perspective of tumor, neuronal and general immunology. Antiganglioside antibodies in human sera are invariably IgM and are found in healthy individuals. Their titers decline with age.
Nishimoto, Kevin   +5 more
core  

Influence of Brain Gangliosides on the Formation and Properties of Supported Lipid Bilayers

open access: yes, 2019
This is a comprehensive study of the effects of the four major brain gangliosides (GM1, GD1b, GD1a, and GT1b) on the adsorption and rupture of phospholipid vesicles on SiO2 surfaces for the formation of supported lipid bilayer (SLB) membranes.
Luke, Jordan   +4 more
core   +1 more source

Cytosolic gangliosides: occurrence in calf brain as ganglioside--protein complexes

open access: yes, 1979
Calf brain was treated in order to prepare separately the cytosol from neuronal bodies and glial cells, and the cytosol from nerve endings. The first cytosol contained 29 μg of ganglioside bound sialic acid/g fresh tissue, the latter 3.1 μg.
S. Marchesini   +3 more
core   +1 more source

Randomized Clinical Trial for Treatment of Patients with Acute Ischemic Cerebral Stroke by Acupoint Injection of Cobalamin or Gangliosides

open access: yes针刺研究, 2016
Objective To observe the clinical therapeutic effect of acupoint injection of medicine in the treatment of patients with acute cerebral ischemia stroke(ACIS).Methods Ninety ACIS patients were randomized into control,Cobalamin and Gangliosides groups(n ...
ZHAO Lei   +4 more
doaj  

Binding of interleukin 2 to gangliosides

open access: yes, 1984
Exogenous gangliosides inhibit interleukin 2 (IL2)-dependent growth of a T cell line, AKIL-1.E8. IL2 activity is retained by columns of ganglioside covalently linked to poly(L-lysine)-agarose and is not eluted with ethylene glycol but is completely ...
Gabriella Caldini   +9 more
core   +1 more source

A monoclonal antibody to human macrophage gangliosides inhibits macrophage migration

open access: yes, 1996
Gangliosides have diverse immunoregulatory properties. The gangliosides endogenous to macrophages may have immunoregulatory properties that distinguish them from other gangliosides.
Melissa A Patterson   +3 more
core   +1 more source

NGcGM3 Ganglioside: A Privileged Target for Cancer Vaccines

open access: yesClinical and Developmental Immunology, 2010
Active specific immunotherapy is a promising field in cancer research. N-glycolyl (NGc) gangliosides, and particularly NGcGM3, have received attention as a privileged target for cancer therapy.
Luis E. Fernandez   +7 more
doaj   +1 more source

Ganglioside Metabolism in a Transgenic Mouse Model of Alzheimer's Disease: Expression of Chol-1α Antigens in the Brain

open access: yesASN Neuro, 2010
The accumulation of Aβ (amyloid β-protein) is one of the major pathological hallmarks in AD (Alzheimer's disease). Gangliosides, sialic acid-containing glycosphingolipids enriched in the nervous system and frequently used as biomarkers associated with ...
Toshio Ariga   +6 more
doaj   +1 more source

Scheme of biosynthetic pathways for major nervous system gangliosides.

open access: yes, 2014
Blockades in ganglioside biosynthesis in knockout mice are indicated by solid red lines. GM2/GD2-synthase knockout mice (B4galnt1-null) mice do not express any complex gangliosides, including GM1, GD1a, GD1b or GT1b, and express only simple gangliosides ...
Tong Gao (341025)   +6 more
core   +1 more source

Serum gangliosides in patients with brain tumors

open access: yes, 2008
In order to determine possible differences in serum gangliosides content and composition before and after surgical removal of tumor, gangliosides isolated from preoperative and postoperative sera of patients with brain tumors were analyzed. Serum samples
Kalanj Bognar, Svjetlana   +5 more
core  

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