Results 101 to 110 of about 44,745 (260)

Mixed Micelles of Gangliosides

, 1990
The aggregation number and the hydrodynamic radius of micelles formed by mixtures of two distinct gangliosides (biological glycolipids) have been measured by static and dynamic light scattering and small-angle neutron scattering.
M. Corti, L.F. Cantu', V. Degiorgio
core   +1 more source

GW4869 Depletes Macrophages and Increases Number of Extracellular Vesicles in Murine Peritoneal Cavity Fluid

Journal of Extracellular Biology, Volume 5, Issue 9, September 2026.
ABSTRACT Pharmacological strategies to modulate extracellular vesicle (EV) release in vivo are gaining traction, yet their broader effects on local immune microenvironments remain unclear. In this study, we assessed how repeated intraperitoneal (i.p.) dosing of the neutral sphingomyelinase inhibitor GW4869 reshapes the peritoneal cavity.
Johann Mar Gudbergsson, Pedro Henrique Gobira, Rodrigo Grassi‐Oliveira, Anders Etzerodt   +3 more
wiley   +1 more source

: Gangliosides impair Langerhans cell function

, 2006
Gangliosides are ubiquitous, membrane-associated, glycosphingolipids, the composition and production of which is altered in many tumour cells. They have been shown to inhibit the in vitro generation and differentiation of dendritic cells (DCs) from ...
Jacques Portoukalian, Portoukalian, Jacques, Popa, Iuliana, Karim Bennaceur, Bennaceur, Karim, Josette Péguet-Navarro, Odile Berthier-Vergnes, Péguet-Navarro, Josette, Iuliana Popa, Berthier-Vergnes, Odile   +9 more
core   +1 more source

Systematic Analysis of Plasma‐Derived Extracellular Vesicle‐Enriched Samples in Age‐Related Macular Degeneration Reveals Oxidative Stress Linked to Altered Lipid and Protein Profiles

Journal of Extracellular Biology, Volume 5, Issue 9, September 2026.
ABSTRACT Vision impairment caused by age‐related macular degeneration (AMD) is a global health priority. Retinal pathology is driven by ageing and exacerbated by genetic and environmental risk factors. Peripheral blood circulation is increasingly recognised as a contributor to disease initiation and progression, and a source of biomarkers to support ...
Marzena Kurzawa‐Akanbi, Jennifer Haggarty, Carina Hansohn, Mohamed T. Patel, Angela J. Cree, Peisi Teo, Milly Armstrong, Nathan Coles, Mark Platt, Helen Griffiths, Heather J. Cordell, Ahmad Khundakar, Pola Goldberg Oppenheimer, Phillip Whitfield, Andrew Lotery, Henning Urlaub, Sina Mozaffari‐Jovin, Majlinda Lako   +17 more
wiley   +1 more source

Helicobacter pylori and complex gangliosides

, 2004
Recognition of sialic acid-containing glycoconjugates by the human gastric pathogen Helicobacter pylori has been repeatedly demonstrated. To investigate the structural requirements for H.
Roche, Niamh,, Ångström, Jonas,, Teneberg, Susann,, Borén, Thomas, Larsson, Thomas,, Hurtig, Marina   +5 more
core   +1 more source

Gangliosides enhance M2-polarized macrophage elongation induced by IL-4 and IL-13 [PDF]

Kosin Medical Journal
Background Macrophage polarization plays a crucial role in the immune response, and gangliosides regulate macrophage function. In this study, we investigated the role of gangliosides in modulating macrophage morphology and function in response to M2 ...
Snehal Chandrakant Meshram, Hee-Jin Choi, Minkyoung Cho, Jaewon Shim, Ki-Tae Ha, Sung-Jin Bae   +5 more
doaj   +1 more source

Heparan Sulfate Proteoglycans: Master Regulators of Cellular Signaling, Tissue Development, and Neural Function

Journal of Neuroscience Research, Volume 104, Issue 9, September 2026.
Ubiquitous cell‐associated, cytoplasmic, synaptic and extracellular matrix HS‐proteoglycans are multifunctional regulators of tissue form and function. HS‐proteoglycans have diverse functions as growth factor co‐receptors in cell proliferation, differentiation, tissue development, mechanical stabilization, synaptogenesis, synaptic plasticity, and ...
James Melrose
wiley   +1 more source

Binding of interleukin 2 to gangliosides [PDF]

, 1984
Exogenous gangliosides inhibit interleukin 2 (IL2)-dependent growth of a T cell line, AKIL-1.E8. IL2 activity is retained by columns of ganglioside covalently linked to poly(L-lysine)-agarose and is not eluted with ethylene glycol but is completely ...
Gabriella Caldini, Chitra Krishnamurti, Ankel, Helmut, Patricia B. Ahrens, Parker, Judy, Ahrens, Patricia B., Judy Parker, Helmut Ankel, Caldini, Gabriella, Krishnamurti, Chitra   +9 more
core   +1 more source

Characterizing Combined Central and Peripheral Demyelination—Insights From a Multimodal Comparison With Chronic Inflammatory Demyelinating Polyneuropathy and Multiple Sclerosis

Muscle &Nerve, Volume 74, Issue 3, Page 605-615, September 2026.
ABSTRACT Introduction/Aims Combined central and peripheral demyelination (CCPD) is a rare dysimmune disorder sharing features with multiple sclerosis (MS) and chronic inflammatory demyelinating polyradiculoneuropathy (CIDP). Direct comparisons of central and peripheral diagnostic findings across these entities remain limited. We, therefore, performed a
N. Dubuisson, A. Kassab, P. Y. K. Van den Bergh, A. F. J. E. Vrancken, W. L. van der Pol, L. H. van den Berg, H. S. Goedee   +6 more
wiley   +1 more source

Gangliosides and synaptic transmission

, 1990
A review, with 223 refs., on the chem. of gangliosides, gangliosides in neuronal function, synaptic transmission, and the role of gangliosides in synaptic ...
Gregory, JB, Panakkezhum, DT
core