Results 91 to 100 of about 44,745 (260)

Anti-ganglioside antibodies in patients with Zika virus infection-associated Guillain-Barré Syndrome in Brazil.

open access: yesPLoS Neglected Tropical Diseases, 2019
Zika virus infection is associated with the development of Guillain-Barré syndrome (GBS), a neurological autoimmune disorder caused by immune recognition of gangliosides and other components at nerve membranes.
Juan Rivera-Correa   +7 more
doaj   +1 more source

Evaluation of the Expression and Prognosis of Neural‐Related Products Expressed by Cancer‐Derived Mesenchymal Stem Cells With the Characteristics of Neural Stem Cells

open access: yesCancer Medicine, Volume 15, Issue 9, September 2026.
ABSTRACT Studies have demonstrated that the nervous system plays an important role in cancer progression. Nevertheless, the effect of mesenchymal stem cells (MSCs) on cancer has yielded conflicting results. In this study, we discovered that cancer‐derived MSCs (CA‐MSCs) not only exhibit the properties of neural stem cells (NSCs) but also express a ...
Liu Yongjun   +11 more
wiley   +1 more source

Recent Advancements in Drug Delivery Across the Blood–Brain Barrier in Amyotrophic Lateral Sclerosis (ALS)

open access: yesCNS Neuroscience &Therapeutics, Volume 32, Issue 9, September 2026.
Progressive BBB/BSCB dysfunction is increasingly recognized as both a pathological feature and a therapeutic barrier in ALS. Novel delivery technologies and barrier‐restoration strategies may enhance CNS drug exposure, improve the efficacy of disease‐modifying therapies, and advance ALS treatment. ABSTRACT Background Amyotrophic lateral sclerosis (ALS)
Nitesh Sanghai   +9 more
wiley   +1 more source

Antibodies against Defined Nerve Cell Components: Gangliosides

open access: yes, 1980
Antisera have been raised in rabbits against the purified brain gangliosides GM1, GD1aand GT1b. The reactivity of these sera with a range of purified gangliosides has been examined by complement fixation and their specificities partially defined by ...
N A Gregson, C T Hammer
core   +1 more source

Partial synthesis of ganglioside and lysoganglioside lipoforms as internal standards for MS quantification

open access: yesJournal of Lipid Research, 2014
Within recent years, ganglioside patterns have been increasingly analyzed by MS. However, internal standards for calibration are only available for gangliosides GM1, GM2, and GM3.
Martin Gantner   +3 more
doaj   +1 more source

Gangliosides activate cultured rat brain microglia.

open access: yes, 1999
Microglia, brain resident macrophages, are activated in brain injuries and several neurodegenerative diseases. However, microglial activators that are produced in the brain are not yet defined.
Joe, E, Pyo, H, Lee, SH, Jung, S, Jou, I
core   +1 more source

Gangliosides in subacute sclerosing leukoencephalitis: isolation and fatty acid composition of nine fractions

open access: yesJournal of Lipid Research, 1968
Gangliosides from brain of an 8 yr old boy with subacute sclerosing leukoencephalitis have been studied in terms of pattern and structure. Thin-layer chromatography showed that both gray and white matter have a highly abnormal pattern, with elevation of ...
Robert Ledeen   +2 more
doaj   +1 more source

Nonpolar and Polar Lipids Composition in Recombinant Chinese Hamster Ovary Cells by Nile Red Staining Flow Cytometry

open access: yesEuropean Journal of Lipid Science and Technology, Volume 128, Issue 9, September 2026.
Cellular lipid composition is a dynamic process. Understanding it is important to improve recombinant protein production. Molecules with solvatochromic properties allow the determination of lipids of different polarities by flow cytometry and offer a useful method for monitoring lipids during different phases of cell growth in bioprocesses.
Francisco E. López‐Salas   +9 more
wiley   +1 more source

Anabolic sialosylation of gangliosides in situ in rat brain cortical slices.

open access: yesJournal of Lipid Research, 1989
Radiolabeling of the sialic acid residues of gangliosides was examined in thin slices of rat brain cerebral cortex incubated under physiologic conditions in the presence of either [14C]N-acetyl-mannosamine (ManNAc) or cytidine 5'-monophosphoryl-[14C]N ...
R Durrie, A Rosenberg
doaj   +1 more source

Small Extracellular Vesicle and Total Lipid Profiles Provide a Diagnostic Advantage Over CA‐125 Across Ovarian Cancer Subtypes

open access: yesJournal of Extracellular Vesicles, Volume 15, Issue 9, September 2026.
Small extracellular vesicle (sEV) lipid profiles outperform CA‐125 across ovarian cancer histotypes, achieving accuracy up to 0.73 in differential diagnosis and 0.94 in screening. In patients with normal CA‐125 levels, sEV lipids maintain discriminative performance where CA‐125 alone fails. ABSTRACT Ovarian cancer remains the most lethal gynaecological
Shikha Rani   +11 more
wiley   +1 more source

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