Results 71 to 80 of about 26,990 (219)
Journal of Lipid Research, 1968 Gangliosides from brain of an 8 yr old boy with subacute sclerosing leukoencephalitis have been studied in terms of pattern and structure. Thin-layer chromatography showed that both gray and white matter have a highly abnormal pattern, with elevation of ...
Robert Ledeen +2 more
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Anabolic sialosylation of gangliosides in situ in rat brain cortical slices.
Journal of Lipid Research, 1989 Radiolabeling of the sialic acid residues of gangliosides was examined in thin slices of rat brain cerebral cortex incubated under physiologic conditions in the presence of either [14C]N-acetyl-mannosamine (ManNAc) or cytidine 5'-monophosphoryl-[14C]N ...
R Durrie, A Rosenberg
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Journal of Lipid Research, 1993 We previously reported a hamster animal model of melanoma in which the tumor tissue expresses gangliosides GM3, GD3, and O-acetyl GD3. This ganglioside pattern is similar to that in human melanomas (Ren, S., A. Slominski, and R. K. Yu.
S Ren +8 more
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Frontiers in NeuroscienceGanglioside GM3 synthase is a key enzyme involved in the biosynthesis of gangliosides. GM3 synthase deficiency (GM3SD) causes an absence of GM3 and all downstream biosynthetic derivatives, including all the a-, b-, c-series gangliosides, commonly found ...
Jin-ichi Inokuchi +12 more
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Gangliosides enhance M2-polarized macrophage elongation induced by IL-4 and IL-13 [PDF]
Kosin Medical JournalBackground Macrophage polarization plays a crucial role in the immune response, and gangliosides regulate macrophage function. In this study, we investigated the role of gangliosides in modulating macrophage morphology and function in response to M2 ...
Snehal Chandrakant Meshram +5 more
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NGcGM3 Ganglioside: A Privileged Target for Cancer Vaccines
Clinical and Developmental Immunology, 2010 Active specific immunotherapy is a promising field in cancer research. N-glycolyl (NGc) gangliosides, and particularly NGcGM3, have received attention as a privileged target for cancer therapy.
Luis E. Fernandez +7 more
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An Optimized Liquid Chromatography–Mass Spectrometry Method for Ganglioside Analysis in Cell Lines
CellsGangliosides are glycosphingolipids composed of a sialylated glycan head group and a ceramide backbone. These anionic lipids form lipid rafts and play crucial roles in regulating various proteins involved in signal transduction, adhesion, and cell–cell ...
Akeem Sanni +11 more
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TGF-β-induced ganglioside remodeling highlights GD2 as a dynamically regulated target in glioblastoma [PDF]
Katinka Tarnóczi +11 more
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LifeThis study aimed to determine the expression and distribution of gangliosides in specific regions of the brains of rainbow trout (Oncorhynchus mykiss Walbaum) and common carp (Cyprinus carpio L.) with regard to seasonal temperature changes.
Valentina Pavić +5 more
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Tuning membrane domain structure and surface charge through the interplay of lipid composition, ions, and the charge state of ganglioside GM1 [PDF]
Miriam Grava +2 more
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