Results 1 to 10 of about 9,249 (183)

Single-Molecule Discrimination of Multisialylated Ganglioside Oligosaccharides Using an Engineered Nanopore

Research
The function of ganglioside oligosaccharides critically depends on the number, linkage, and spatial arrangement of sialic acid residues, yet direct discrimination of highly sialylated ganglioside oligosaccharides, particularly at the isomeric level ...
Guangda Yao, Boyang Ren, Daigui Zhu, Jianling Tan, Jingjing Hou, Yuan Ma, Zhengyu Hang, Zhuojia Xu, Zhaobing Gao, Tiehai Li, Bingqing Xia   +10 more
doaj   +1 more source

Elevation of ganglioside degradation pathway drives GM2 and GM3 within amyloid plaques in a transgenic mouse model of Alzheimer's disease

Neurobiology of Disease
Alzheimer's disease (AD) is a progressive neurodegenerative disease that accounts for two-thirds of all dementia cases, and age is the strongest risk factor. In addition to the amyloid hypothesis, lipid dysregulation is now recognized as a core component
Wenxuan Wang, Sarah J. Myers, Nikita Ollen-Bittle, Shawn N. Whitehead   +3 more
doaj   +1 more source

Brucellosis infection complicated with myelitis: a case report and literature review

Frontiers in Cellular and Infection Microbiology
Brucellosis is a zoonotic disease caused by a Gram-negative coccus a facultative intracellular pathogen. Neurobrucellosis has an incidence rate of 3-7% among all patients with brucellosis, while spinal cord involvement is rare and carries a significant ...
Xiaoyu Ma, Xiaoyu Ma, Xiaoyu Ma, Ying Wang, Qiong Wu, Xiaomei Ma, Xiaomei Ma, Xiaomei Ma, Qiang Wang, Qinghong Guo, Qinghong Guo   +10 more
doaj   +1 more source

Normal and Dysregulated Sphingolipid Metabolism: Contributions to Podocyte Injury and Beyond

Cells
Podocyte health is vital for maintaining proper glomerular filtration in the kidney. Interdigitating foot processes from podocytes form slit diaphragms which regulate the filtration of molecules through size and charge selectivity. The abundance of lipid
Matthew Tolerico, Sandra Merscher, Alessia Fornoni   +2 more
doaj   +1 more source

Potential roles of gangliosides in chemical-induced neurodegenerative diseases and mental health disorders

Frontiers in Neuroscience
Yutaka Itokazu, Yutaka Itokazu, Alvin V. Terry   +2 more
doaj   +1 more source

Modifications of Ganglioside Patterns in Human Meningiomas

Journal of Neurochemistry, 1983
: Ganglioside content and distribution were determined in control meninges and in 30 human meningiomas belonging to four different histological types.
Laura Riboni
exaly   +2 more sources

Sialosyllactotetraosylceramide, a novel ganglioside antigen detected in human carcinomas by a monoclonal antibody

FEBS Letters, 1985
J E Mansson, L Lindholm
exaly  

Different reactivities of monoclonal antibodies to ganglioside lactones

Lipids and Lipid Metabolism, 1988
Tadashi Tai, Ikuo Kawashima, I Kawashima   +2 more
exaly  

Antibodies to ganglioside GM1 in patients with Alzheimer's disease

Neuroscience Letters, 1988
Joab Chapman, Ben-Ami Sela, D M Michaelson   +2 more
exaly  

Sialosyllactotetraosylceramide, 3'-isoLM1, a Ganglioside of the Lactotetraose Series Isolated from Normal Human Infant Brain

Journal of Neurochemistry, 1987
J E Mansson, P Fredman
exaly