Results 51 to 60 of about 26,990 (219)
How Do Gangliosides Regulate RTKs Signaling?
Cells, 2013 Gangliosides, the glycosphingolipids carrying one or several sialic acid residues, are located on the outer leaflet of the plasma membrane in glycolipid-enriched microdomains, where they interact with molecules of signal transduction pathways including ...
Sylvain Julien +4 more
doaj +1 more source
Prevalence and Disability of Peripheral Neuropathy in Patients With Waldenström's Macroglobulinemia
European Journal of Haematology, EarlyView.ABSTRACT Objectives Peripheral neuropathy (PN) is considered a frequent complication of Waldenström's macroglobulinemia (WM). Establishing a causal relationship between PN and WM is complicated by confounding factors such as age‐related axonal loss and diabetes. This scoping review aims to summarize the current evidence on WM‐associated PN with a focus
Morten Müller Aagaard +6 more
wiley +1 more source
Periodontology 2000, EarlyView.AbstractPeriodontitis is a complex inflammatory disease in which the host genome, in conjunction with extrinsic factors, determines susceptibility and progression. Genetic predisposition is the strongest risk factor in the first decades of life. As people age, chronic exposure to the periodontal microbiome puts a strain on the proper maintenance of ...
Arne S. Schaefer +4 more
wiley +1 more source
Legume Science, Volume 8, Issue 4, December 2026.ABSTRACT Legumes (family Fabaceae) are vital, nutrient‐dense global resources rich in proteins, complex carbohydrates and micronutrients. Although offering agronomic benefits like nitrogen fixation, their dietary utilization is often constrained by anti‐nutritional factors (ANFs) such as phytates, tannins, lectins and oligosaccharides, which reduce ...
Diana Kavaya +3 more
wiley +1 more source
Molecular recognition of gangliosides and their potential for cancer immunotherapies
Frontiers in Immunology, 2014 Gangliosides are sialic acid-containing glycosphingolipids expressed on all vertebrate cells. They are primarily positioned in the plasma membrane, with the ceramide part anchored in the membrane and the glycan part exposed on the surface of the cell ...
Ute eKrengel, Paula A Bousquet
doaj +1 more source
O-acetylated Gangliosides as Targets for Cancer Immunotherapy
Cells, 2020 O-acetylation of sialic acid residues is one of the main modifications of gangliosides, and modulates ganglioside functions. O-acetylation of gangliosides is dependent on sialyl-O-acetyltransferases and sialyl-O-acetyl-esterase activities.
Sumeyye Cavdarli +2 more
doaj +1 more source
Glucosylceramide synthase inhibition protects against cardiac hypertrophy in chronic kidney disease
Scientific Reports, 2022 A significant population of patients with chronic kidney disease (CKD) develops cardiac hypertrophy, which can lead to heart failure and sudden cardiac death.
Gabriel C. Baccam +7 more
doaj +1 more source
Clinical Case Reports, Volume 14, Issue 11, November 2026.ABSTRACT PANDAS‐like syndromes may rarely occur beyond childhood. Although these patients may meet criteria for PANS, recognizing a possible streptococcal‐triggered subgroup remains important for diagnosis, future biomarker discovery, and refinement of disease classification.
Tariq A. Madani +3 more
wiley +1 more source
Removal of borate from tritiated gangliosides via the mannitoborate complex.
Journal of Lipid Research, 1994 Purified gangliosides were radiolabeled by exposure to sodium boro [3H]hydride in the presence of palladium on barium sulfate. After centrifugation to remove the catalyst, borate was complexed with mannitol and the resulting mannitoborate complex and ...
H C Yohe
doaj +1 more source
Role of gangliosides in prostate pathology [PDF]
Romanian Journal of Infectious Diseases, 2016 Molecular pathology of benign prostatic hyperplasia is multifactorial and involves endocrine, biochemical, immunological interactions. The mechanisms involved in the onset and progression of benign prostatic hyperplasia are: infections, 50 years of age ...
Ilinca Nicolae +2 more
doaj +1 more source