Results 31 to 40 of about 44,745 (260)
Gangliosides: Treatment Avenues in Neurodegenerative Disease
Frontiers in Neurology, 2019 Gangliosides are cell membrane components, most abundantly in the central nervous system (CNS) where they exert among others neuro-protective and -restorative functions.
Pierre Magistretti +5 more
semanticscholar +1 more source
LC-MS analysis of gangliosides : methods development and software solutions [PDF]
, 2023 Gangliosides are high molecular weight, specialized metabolites found at greatest concentration in the central nervous system. They are glycosphingolipids, possessing a nonpolar ceramide tail and a polar carbohydrate or ‘glycan’ head.
Smith, Ryan A. +1 more
core
Recovery of gangliosides from aqueous solutions on styrene-divinylbenzene copolymer columns1
Journal of Lipid Research, 2002 An investigation was made using a styrene-divinylbenzene copolymer as a solid phase sorbent to recover gangliosides from aqueous solutions. A comparison with octadecyl-bonded (C18) silica gel showed that the general procedure used to purify gangliosides ...
Iuliana Popa +3 more
doaj +1 more source
Journal of Lipid Research, 1982 The neutral and acidic glycolipids from the liver of an 11-year-old male were quantitatively isolated and characterized. The total concentration of gangliosides was also determined in sampled from five other human livers.
O Nilsson, L Svennerholm
doaj +1 more source
Frontiers in Nutrition, 2021 Background and Aims: Dietary gangliosides are present in human milk and consumed in low amounts from organ meats. Clinical and animal studies indicate that dietary gangliosides attenuate signaling processes that are a hallmark of inflammatory bowel ...
John J. Miklavcic +7 more
doaj +1 more source
Neuropathophysiological potential of Guillain-Barré syndrome anti-ganglioside-complex antibodies at mouse motor nerve terminals [PDF]
, 2011 Objectives: Anti-ganglioside antibodies are present in approximately half of Guillain–Barré syndrome (GBS) patients. Recently, it has been shown that a considerable proportion of these patients has serum antibodies against antigenic epitopes formed by a
Susumu Kusunoki +32 more
core +1 more source
Comprehensive Profiling of Surface Gangliosides Extracted from Various Cell Lines by LC-MS/MS
Cells, 2019 Gangliosides act as a surface marker at the outer cellular membrane and play key roles in cancer cell invasion and metastasis. Despite the biological importance of gangliosides, they have been still poorly characterized due to the lack of effective ...
Jua Lee +9 more
doaj +1 more source
Gangliosides: The Double-Edge Sword of Neuro-Ectodermal Derived Tumors
Biomolecules, 2019 Gangliosides, the glycosphingolipids carrying one or several sialic acid residues, are mostly localized at the plasma membrane in lipid raft domains and implicated in many cellular signaling pathways mostly by interacting with tyrosine kinase receptors ...
Sumeyye Cavdarli +2 more
semanticscholar +1 more source
Frontiers in Oncology, 2016 Glycolipids are complex molecules consisting of a ceramide lipid moiety linked to a glycan chain of variable length and structure. Among these are found the gangliosides, which are sialylated glycolipids ubiquitously distributed on the outer layer of ...
Jose Luis Daniotti +2 more
doaj +1 more source
Gangliosides and Neuroblastomas [PDF]
International Journal of Molecular Sciences, 2020 The focus of this review is the ganglio-series of glycosphingolipids found in neuroblastoma (NB) and the myriad of unanswered questions associated with their possible role(s) in this cancer. NB is one of the more common solid malignancies of children. Five-year survival for those diagnosed with low risk NB is 90–95%, while that for children with high ...
openaire +2 more sources