Results 31 to 40 of about 26,990 (219)
Retention of gangliosides in serum delipidated by diisopropyl ether-1-butanol extraction.
Extraction with diisopropyl ether-1-butanol is a rapid method for the delipidation of serum without protein denaturation. We sought to confirm that this solvent system would also extract the highly polar acidic glycosphingolipids, gangliosides.
C G Wong, S Ladisch
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A simple and effective procedure has been developed for eliminating silica gel from gangliosides after preparative thin-layer chromatography. Gangliosides were extracted from the scraped silica gel with chloroform-methanol-water 10:10:3 (by volume) and ...
H Kubo, M Hoshi
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Ganglioside Biochemistry [PDF]
Gangliosides are sialic acid-containing glycosphingolipids. They occur especially on the cellular surfaces of neuronal cells, where they form a complex pattern, but are also found in many other cell types. The paper provides a general overview on their structures, occurrence, and metabolism. Key functional, biochemical, and pathobiochemical aspects are
openaire +2 more sources
Quantification of gangliosides by microbore high performance liquid chromatography.
A highly sensitive analytical method was developed that allows the separation of ganglioside mixtures and quantification of individual non-derivatized gangliosides in the concentration range between 2 pmol and 1 nmol.
R Wagener, B Kobbe, W Stoffel
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Determination of brain gangliosides by determination of ganglioside stearic acid
A new method is described for the determination of brain gangliosides by measuring stearic acid, the chief acid of gangliosides, in an appropriately purified brain extract.
Yasuo Kishimoto, Norman S. Radin
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Mast cells are immunoregulatory cells that participate in inflammatory processes. Cross-linking mast cell specific GD1b derived gangliosides by mAbAA4 results in partial activation of mast cells without the release of preformed mediators.
Edismauro Garcia Freitas Filho +4 more
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Summary: Lysosome membrane recycling occurs at the end of the autophagic pathway and requires proteins that are mostly encoded by genes mutated in neurodegenerative diseases. However, its implication in neuronal death is still unclear. Here, we show that
Maxime Boutry +19 more
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Role of gangliosides in the differentiation of human mesenchymal-derived stem cells into osteoblasts and neuronal cells [PDF]
Gangliosides are complex glycosphingolipids that are the majorcomponent of cytoplasmic cell membranes, and play a rolein the control of biological processes.
Ghislain Moussavou +6 more
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Extracellular vesicle (EV) lipidomic profiling of plasma and ascites from patients with high‐grade serous ovarian cancer and of ovarian cancer cell lines reveals enrichment of triglycerides (TGs), diacylglycerols (DGs), phosphatidylcholine (PCs), sphingomyelins (SMs), reflecting tumor metabolic reprogramming.
Shikha Rani +9 more
wiley +1 more source
The structure of gangliosides hides a code for determining neuronal functions
Gangliosides are particularly abundant in the central nervous system, where they are mainly associated with the synaptic membranes. Their structure underlies a specific role in determining several cell physiological processes of the nervous system.
Giulia Lunghi +5 more
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