Results 31 to 40 of about 26,990 (219)

Retention of gangliosides in serum delipidated by diisopropyl ether-1-butanol extraction.

open access: yesJournal of Lipid Research, 1983
Extraction with diisopropyl ether-1-butanol is a rapid method for the delipidation of serum without protein denaturation. We sought to confirm that this solvent system would also extract the highly polar acidic glycosphingolipids, gangliosides.
C G Wong, S Ladisch
doaj   +1 more source

Elimination of silica gel from gangliosides by using a reversed-phase column after preparative thin-layer chromatography.

open access: yesJournal of Lipid Research, 1985
A simple and effective procedure has been developed for eliminating silica gel from gangliosides after preparative thin-layer chromatography. Gangliosides were extracted from the scraped silica gel with chloroform-methanol-water 10:10:3 (by volume) and ...
H Kubo, M Hoshi
doaj   +1 more source

Ganglioside Biochemistry [PDF]

open access: yesISRN Biochemistry, 2012
Gangliosides are sialic acid-containing glycosphingolipids. They occur especially on the cellular surfaces of neuronal cells, where they form a complex pattern, but are also found in many other cell types. The paper provides a general overview on their structures, occurrence, and metabolism. Key functional, biochemical, and pathobiochemical aspects are
openaire   +2 more sources

Quantification of gangliosides by microbore high performance liquid chromatography.

open access: yesJournal of Lipid Research, 1996
A highly sensitive analytical method was developed that allows the separation of ganglioside mixtures and quantification of individual non-derivatized gangliosides in the concentration range between 2 pmol and 1 nmol.
R Wagener, B Kobbe, W Stoffel
doaj   +1 more source

Determination of brain gangliosides by determination of ganglioside stearic acid

open access: yesJournal of Lipid Research, 1966
A new method is described for the determination of brain gangliosides by measuring stearic acid, the chief acid of gangliosides, in an appropriately purified brain extract.
Yasuo Kishimoto, Norman S. Radin
doaj   +1 more source

Cross-Linking Mast Cell Specific Gangliosides Stimulates the Release of Newly Formed Lipid Mediators and Newly Synthesized Cytokines

open access: yesMediators of Inflammation, 2016
Mast cells are immunoregulatory cells that participate in inflammatory processes. Cross-linking mast cell specific GD1b derived gangliosides by mAbAA4 results in partial activation of mast cells without the release of preformed mediators.
Edismauro Garcia Freitas Filho   +4 more
doaj   +1 more source

Inhibition of Lysosome Membrane Recycling Causes Accumulation of Gangliosides that Contribute to Neurodegeneration

open access: yesCell Reports, 2018
Summary: Lysosome membrane recycling occurs at the end of the autophagic pathway and requires proteins that are mostly encoded by genes mutated in neurodegenerative diseases. However, its implication in neuronal death is still unclear. Here, we show that
Maxime Boutry   +19 more
doaj   +1 more source

Role of gangliosides in the differentiation of human mesenchymal-derived stem cells into osteoblasts and neuronal cells [PDF]

open access: yesBMB Reports, 2013
Gangliosides are complex glycosphingolipids that are the majorcomponent of cytoplasmic cell membranes, and play a rolein the control of biological processes.
Ghislain Moussavou   +6 more
doaj   +1 more source

Extracellular vesicle lipidomics liquid biopsy reveals systemic and tumor microenvironment metabolic reprogramming in ovarian cancer

open access: yesMolecular Oncology, EarlyView.
Extracellular vesicle (EV) lipidomic profiling of plasma and ascites from patients with high‐grade serous ovarian cancer and of ovarian cancer cell lines reveals enrichment of triglycerides (TGs), diacylglycerols (DGs), phosphatidylcholine (PCs), sphingomyelins (SMs), reflecting tumor metabolic reprogramming.
Shikha Rani   +9 more
wiley   +1 more source

The structure of gangliosides hides a code for determining neuronal functions

open access: yesFEBS Open Bio, 2021
Gangliosides are particularly abundant in the central nervous system, where they are mainly associated with the synaptic membranes. Their structure underlies a specific role in determining several cell physiological processes of the nervous system.
Giulia Lunghi   +5 more
doaj   +1 more source

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