Results 21 to 30 of about 44,745 (260)

Gangliosides in Membrane Organization. [PDF]

Progress in Molecular Biology and Translational Science, 2018
Since the structure of GM1 was elucidated 55years ago, researchers have been attracted by the sialylated glycans of gangliosides. Gangliosides head groups, protruding toward the extracellular space, significantly contribute to the cell glycocalyx; and in
S. Sonnino, E. Chiricozzi, Sara Grassi, L. Mauri, S. Prioni, A. Prinetti   +5 more
semanticscholar   +2 more sources

Gangliosides: Structures, Biosynthesis, Analysis, and Roles in Cancer

ChemBioChem, 2017
Philippe Delannoy, Sophie Groux-Degroote, Yann Guerardel   +2 more
exaly   +2 more sources

Gangliosides in Cancer Cell Signaling. [PDF]

Progress in Molecular Biology and Translational Science, 2018
International audienceAt the outer leaflet of the plasma membrane, gangliosides are found with other glycosphingolipids, phospholipids, and cholesterol in glycolipid-enriched microdomains, in which they interact with signaling molecules including ...
S. Groux-Degroote, Macarena Rodríguez-Walker, Justine H. Dewald, J. L. Daniotti, P. Delannoy   +4 more
semanticscholar   +2 more sources

Alkali-labile gangliosides [PDF]

, 2023
The structure and properties of a group of gangliosides modified by mild alkaline treatment are discussed. We will present the occurrence and the structure of gangliosides carrying the N-acetyneuraminic acid O-acetylated in position 9, the Neu5,9Ac(2 ...
Sandro Sonnino, Laura Mauri
core   +1 more source

Total ganglioside ablation at mouse motor nerve terminals alters neurotransmitter release level [PDF]

, 2010
Neuronal membrane gangliosides, forming a large family of sialylated glycosphingolipids, have been hypothesized to play important roles in synaptic transmission.
Furukawa, K., Plomp, J.J., Todorov, B., Willison, H.J., Zitman, F.M.P.   +4 more
core   +2 more sources

Neuromuscular synaptic function in mice lacking major subsets of gangliosides [PDF]

, 2008
Gangliosides are a family of sialylated glycosphingolipids enriched in the outer leaflet of neuronal membranes, in particular at synapses. Therefore, they have been hypothesized to play a functional role in synaptic transmission.
Furukawa, K., Plomp, J.J., Willison, H.J., Willison, HJ, Verschuuren, JJ, Todorov, B, Furukawa, K, Jacobs, B.C., Zitman, FMP, Todorov, B., Zitman, F.M.P., Verschuuren, J.J., Plomp, JJ   +12 more
core   +1 more source

The C-Type Lectin Mincle Serves as a Pattern Recognition Receptor for the Lipid Envelope of Human Cytomegalovirus. [PDF]

Eur J Immunol
Whether viral lipids can directly interact with pattern recognition receptors to modulate antiviral immune responses remains unclear. We show that Mincle‐dependent recognition of HCMV viral particles induces proinflammatory cytokine production in primary human macrophages.
Bokun V, Chai W, Buchanan R, Murphy E, Liu Y, Holder B, Decout A.   +6 more
europepmc   +2 more sources

Neuromuscular synaptic transmission in aged ganglioside-deficient mice [PDF]

, 2011
Gangliosides are sialylated glycosphingolipids that are present in high density on neuronal membranes, especially at synapses, where they are assumed to play functional or modulating roles.
Todorov, Boyan, Furukawa, Keiko, Furukawa, K., Plomp, J.J., Verschuuren, Jan J., Willison, H.J., Furukawa, Koichi, Plomp, Jaap J., Jacobs, B.C., Todorov, B., Willison, Hugh J., Jacobs, Bart C., Zitman, F.M.P., Verschuuren, J.J., Zitman, Femke M.P.   +14 more
core   +1 more source

Diet-Induced Changes in Spectrum Patterns of Serum Gangliosides in 6-Month-Old Infants

Majalah Kedokteran Bandung, 2012
Human milk contains higher levels of gangliosides than infant formula. Gangliosides play a role in neuronal growth, migration and maturation, sinaptogenesis, and myelination.
Dida A. Gurnida, Ponpon Idjradinata, Deddy Muchtadi, Nanan Sekarwana, Bertram Fong, Paul McJarrow, Angela Rowan, Carmen Norris   +7 more
doaj   +1 more source

Specific synthesis of neurostatin and gangliosides O-acetylated in the outer sialic acids using a sialate transferase. [PDF]

PLoS ONE, 2012
Gangliosides are sialic acid containing glycosphingolipids, commonly found on the outer leaflet of the plasma membrane. O-acetylation of sialic acid hydroxyl groups is one of the most common modifications in gangliosides.
Lorenzo Romero-Ramírez, Isabel García-Álvarez, Ramón Campos-Olivas, Michel Gilbert, Marie-France Goneau, Alfonso Fernández-Mayoralas, Manuel Nieto-Sampedro   +6 more
doaj   +1 more source