Results 1 to 10 of about 53,157 (259)
Quantification of gangliosides by microbore high performance liquid chromatography.
A highly sensitive analytical method was developed that allows the separation of ganglioside mixtures and quantification of individual non-derivatized gangliosides in the concentration range between 2 pmol and 1 nmol.
R Wagener, B Kobbe, W Stoffel
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Gangliosides are a family of complex lipids that are abundant in the brain. There is no doubt the investigations about the distribution of gangliosides in brian and the relationship between gangliosides and Alzheimer’s disease is profound. However, these
Yangyang Zhang +6 more
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Determination of brain gangliosides by determination of ganglioside stearic acid
A new method is described for the determination of brain gangliosides by measuring stearic acid, the chief acid of gangliosides, in an appropriately purified brain extract.
Yasuo Kishimoto, Norman S. Radin
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Role of gangliosides in the differentiation of human mesenchymal-derived stem cells into osteoblasts and neuronal cells [PDF]
Gangliosides are complex glycosphingolipids that are the majorcomponent of cytoplasmic cell membranes, and play a rolein the control of biological processes.
Ghislain Moussavou +6 more
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Mast cells are immunoregulatory cells that participate in inflammatory processes. Cross-linking mast cell specific GD1b derived gangliosides by mAbAA4 results in partial activation of mast cells without the release of preformed mediators.
Edismauro Garcia Freitas Filho +4 more
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The structure of gangliosides hides a code for determining neuronal functions
Gangliosides are particularly abundant in the central nervous system, where they are mainly associated with the synaptic membranes. Their structure underlies a specific role in determining several cell physiological processes of the nervous system.
Giulia Lunghi +5 more
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Summary: Lysosome membrane recycling occurs at the end of the autophagic pathway and requires proteins that are mostly encoded by genes mutated in neurodegenerative diseases. However, its implication in neuronal death is still unclear. Here, we show that
Maxime Boutry +19 more
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A semi-preparative, analytical high performance liquid chromatographic (HPLC) procedure is described for the isolation of molecular species of GM1 and GD1a gangliosides containing a single long chain base, C18 or C20 sphingosine, C18 or C20 sphinganine ...
S Sonnino +5 more
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BackgroundGangliosides are a class of sphingolipids that are present in the cell membranes of vertebrates. Gangliosides influence a broad range of cellular processes through effects on signal transduction, being found abundantly in the brain, and having ...
Benjamin B Albert +14 more
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Lipid composition of human neural tumors.
Gangliosides, cholesterol, and phospholipids were quantitated in the tissues of 11 human neural tumors and the cells of two gliomas cultured in vitro.
A J Yates +4 more
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