Results 1 to 10 of about 53,157 (259)

Quantification of gangliosides by microbore high performance liquid chromatography.

open access: yesJournal of Lipid Research, 1996
A highly sensitive analytical method was developed that allows the separation of ganglioside mixtures and quantification of individual non-derivatized gangliosides in the concentration range between 2 pmol and 1 nmol.
R Wagener, B Kobbe, W Stoffel
doaj   +1 more source

Combination of ESI and MALDI mass spectrometry for qualitative, semi-quantitative and in situ analysis of gangliosides in brain

open access: yesScientific Reports, 2016
Gangliosides are a family of complex lipids that are abundant in the brain. There is no doubt the investigations about the distribution of gangliosides in brian and the relationship between gangliosides and Alzheimer’s disease is profound. However, these
Yangyang Zhang   +6 more
semanticscholar   +1 more source

Determination of brain gangliosides by determination of ganglioside stearic acid

open access: yesJournal of Lipid Research, 1966
A new method is described for the determination of brain gangliosides by measuring stearic acid, the chief acid of gangliosides, in an appropriately purified brain extract.
Yasuo Kishimoto, Norman S. Radin
doaj   +1 more source

Role of gangliosides in the differentiation of human mesenchymal-derived stem cells into osteoblasts and neuronal cells [PDF]

open access: yesBMB Reports, 2013
Gangliosides are complex glycosphingolipids that are the majorcomponent of cytoplasmic cell membranes, and play a rolein the control of biological processes.
Ghislain Moussavou   +6 more
doaj   +1 more source

Cross-Linking Mast Cell Specific Gangliosides Stimulates the Release of Newly Formed Lipid Mediators and Newly Synthesized Cytokines

open access: yesMediators of Inflammation, 2016
Mast cells are immunoregulatory cells that participate in inflammatory processes. Cross-linking mast cell specific GD1b derived gangliosides by mAbAA4 results in partial activation of mast cells without the release of preformed mediators.
Edismauro Garcia Freitas Filho   +4 more
doaj   +1 more source

The structure of gangliosides hides a code for determining neuronal functions

open access: yesFEBS Open Bio, 2021
Gangliosides are particularly abundant in the central nervous system, where they are mainly associated with the synaptic membranes. Their structure underlies a specific role in determining several cell physiological processes of the nervous system.
Giulia Lunghi   +5 more
doaj   +1 more source

Inhibition of Lysosome Membrane Recycling Causes Accumulation of Gangliosides that Contribute to Neurodegeneration

open access: yesCell Reports, 2018
Summary: Lysosome membrane recycling occurs at the end of the autophagic pathway and requires proteins that are mostly encoded by genes mutated in neurodegenerative diseases. However, its implication in neuronal death is still unclear. Here, we show that
Maxime Boutry   +19 more
doaj   +1 more source

High performance liquid chromatography preparation of the molecular species of GM1 and GD1a gangliosides with homogeneous long chain base composition.

open access: yesJournal of Lipid Research, 1984
A semi-preparative, analytical high performance liquid chromatographic (HPLC) procedure is described for the isolation of molecular species of GM1 and GD1a gangliosides containing a single long chain base, C18 or C20 sphingosine, C18 or C20 sphinganine ...
S Sonnino   +5 more
doaj   +1 more source

Supplementation with milk enriched with complex lipids during pregnancy: A double-blind randomized controlled trial.

open access: yesPLoS ONE, 2021
BackgroundGangliosides are a class of sphingolipids that are present in the cell membranes of vertebrates. Gangliosides influence a broad range of cellular processes through effects on signal transduction, being found abundantly in the brain, and having ...
Benjamin B Albert   +14 more
doaj   +1 more source

Lipid composition of human neural tumors.

open access: yesJournal of Lipid Research, 1979
Gangliosides, cholesterol, and phospholipids were quantitated in the tissues of 11 human neural tumors and the cells of two gliomas cultured in vitro.
A J Yates   +4 more
doaj   +1 more source

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