Results 11 to 20 of about 26,990 (219)

The gangliosides

Journal of Lipid Research, 1964
The results of recent studies on the complexities of gangliosides from brain, spleen, and erythrocyte stroma are described, and ganglioside nomenclature is discussed.
Lars Svennerholm
doaj   +3 more sources

Direct Comparison of MRM-MS and PRM-MS Methods for Quantitative Ganglioside Analysis. [PDF]

J Am Soc Mass Spectrom
Sanni A, Koraich A, Nwaiwu J, Delkhosh AS, Mechref Y.   +4 more
europepmc   +3 more sources

Differential distribution of major brain gangliosides in the adult mouse central nervous system. [PDF]

PLoS ONE, 2013
Gangliosides - sialic acid-bearing glycolipids - are major cell surface determinants on neurons and axons. The same four closely related structures, GM1, GD1a, GD1b and GT1b, comprise the majority of total brain gangliosides in mammals and birds ...
Katarina Vajn, Barbara Viljetić, Ivan Večeslav Degmečić, Ronald L Schnaar, Marija Heffer   +4 more
doaj   +1 more source

Ganglioside and Non-ganglioside Mediated Host Responses to the Mouse Polyomavirus. [PDF]

PLoS Pathogens, 2015
Gangliosides serve as receptors for internalization and infection by members of the polyomavirus family. Specificity is determined by recognition of carbohydrate moieties on the ganglioside by the major viral capsid protein VP1.
John You, Samantha D O'Hara, Palanivel Velupillai, Sherry Castle, Steven Levery, Robert L Garcea, Thomas Benjamin   +6 more
doaj   +1 more source

Challenges in the Analysis of Gangliosides by LC-MS

CHIMIA, 2022
Gangliosides are a family of conjugates consisting of a polar sialoglycan head group and a hydrophobic ceramide tail. Gangliosides are of high abundance in neuronal tissues and are involved in numerous biological processes, such as cell-cell recognition,
Thomas Muggli, Claudia Bühr, Stefan Schürch   +2 more
doaj   +1 more source

PRC2-dependent regulation of ganglioside expression during dedifferentiation contributes to the proliferation and migration of vascular smooth muscle cells

Frontiers in Cell and Developmental Biology, 2022
Phenotypic switching between contractile (differentiated state) and proliferative (dedifferentiated state) vascular smooth muscle cells (VSMCs) is a hallmark of vascular remodeling that contributes to atherosclerotic diseases.
Norihiko Sasaki, Kazumi Hirano, Yuuki Shichi, Yoko Itakura, Toshiyuki Ishiwata, Masashi Toyoda   +5 more
doaj   +1 more source

Lipid rafts and human diseases: why we need to target gangliosides

FEBS Open Bio, 2023
Gangliosides are functional components of membrane lipid rafts that control critical functions in cell communication. Many pathologies involve raft gangliosides, which therefore represent an approach of choice for developing innovative therapeutic ...
Jacques Fantini
doaj   +1 more source

Distribution of exogenously added gangliosides in serum proteins depends on the relative affinity of albumin and lipoproteins.

Journal of Lipid Research, 1995
Gangliosides in normal serum are found only in lipoproteins and the relative content of the three major lipoprotein fractions is low density lipoprotein > high density lipoprotein > very low density lipoprotein (LDL > HDL > VLDL).
A Rebbaa, J Portoukalian
doaj   +1 more source

Gangliosides in milk

Mljekarstvo, 2016
Gangliosides belong to a group of glycosphingolipids which are naturally found in biological tissues and fluids including mammalian milks. Considering milk, gangliosides are exclusively found in the membrane of the milk fat globule.
Slavica Potočki, Marko Mesarić
doaj   +1 more source

Production of multiple brain-like ganglioside species is dispensable for fas-induced apoptosis of lymphoid cells. [PDF]

PLoS ONE, 2011
Activation of an acid sphingomyelinase (aSMase) leading to a biosynthesis of GD3 disialoganglioside has been associated with Fas-induced apoptosis of lymphoid cells. The present study was undertaken to clarify the role of this enzyme in the generation of
Iuliana Popa, Nicole Therville, Stéphane Carpentier, Thierry Levade, Olivier Cuvillier, Jacques Portoukalian   +5 more
doaj   +1 more source