Results 121 to 130 of about 111,099 (385)

Long non‐coding RNAs as therapeutic targets in head and neck squamous cell carcinoma and clinical application

FEBS Open Bio, EarlyView.
Long non‐coding RNAs (lncRNAs) occupy an abundant fraction of the eukaryotic transcriptome and an emerging area in cancer research. Regulation by lncRNAs is based on their subcellular localization in HNSCC. This cartoon shows the various functions of lncRNAs in HNSCC discussed in this review.
Ellen T. Tran, Ruchi A. Patel, Amogh Chariyamane, Ratna B. Ray   +3 more
wiley   +1 more source

Fierce Fusarium solani infection in diabetic foot – A double-barrel rifle

Journal of Current Research in Scientific Medicine
Diabetic foot is one of the most serious and prevalent manifestations of diabetes mellitus. In a study conducted in Eastern India, 31.7% of diabetic patients with infections in the lower limb had positive fungal cultures.
Subha Kanthiah, Sonia Subramanian, Nagalakshmi Ranjan, Poongodi Santhana Kumarasamy   +3 more
doaj   +1 more source

Gangrene of the digits of the right lower limb in a patient with homozygous sickle cell disease and ulcerative colitis

Clinics and Practice, 2014
Thrombosis may play an important role in the pathophysiology of certain complications of sickle cell disease (SCD). While the association between SCD and ulcerative colitis (UC) is still debatable, inflammatory bowel disease is known to be associated ...
Angela E. Rankine-Mullings, Jennifer M. Knight-Madden, Marvin Reid, Trevor S. Ferguson   +3 more
doaj   +1 more source

The place of D-dimer and L-lactate levels in the early diagnosis of acute mesenteric ischemia [PDF]

, 2015
INTRODUCTION: Acute mesenteric ischemia (AMI) is an abdominal-vascular emergency which is rare and has high mortality rates (60-80 %) due to late diagnosis (1-3).
Aydin, B., Aydin, C., Demirkan, Neşe Çallı, Kaptanoğlu, Bünyamin, Serinken, M., Özban, Murat   +5 more
core   +1 more source

A contemporary case series of Fournier’s gangrene at a Swiss tertiary care center—can scoring systems accurately predict mortality and morbidity?

World Journal of Emergency Surgery, 2018
BackgroundFournier’s gangrene (FG) is a life-threatening infection of the genital, perineal, and perianal regions with a morbidity range between 3 and 67%.
C. Wetterauer, J. Ebbing, A. Halla, R. Kuehl, S. Erb, A. Egli, D. Schaefer, H. Seifert   +7 more
semanticscholar   +1 more source

Neurotoxic amyloid β‐peptide and tau produce cytokine‐like effects on PMCA in glioblastoma cell lines, enhancing its activity and isoforms expression

FEBS Open Bio, EarlyView.
Two biomarkers of Alzheimer's disease, amyloid β‐peptide (Aβ) and tau, induce the transformation of U‐251 and other glioblastoma cell lines into neurotoxic A1‐like reactive astrocytes. This transformation is produced by cytokines and is followed by upregulation of PMCA activity and isoform expression, and is closely associated with inflammation, as ...
María Berrocal, Alberto Alvarez‐Barrientos, Ana M. Mata   +2 more
wiley   +1 more source

Intestinal perforation after surgical treatment for incisional hernia. iatrogenic or idiopathic? [PDF]

, 2018
Intestinal perforation (IP) is a life-threatening gastroenterological condition requiring urgent surgical care, which may present itself as an uncommon complication following incisional hernia repair surgery, most often because of iatrogenic traumatism ...
Amorosi, V, D'Angelo, F, Firmani, G, Longo, B, Santanelli di Pompeo, F, Sorotos, M   +5 more
core   +1 more source

Management of Symmetrical Peripheral Gangrene

Indian Journal of Critical Care Medicine, 2018
Symmetrical peripheral gangrene (SPG) is a rare, debilitating disease that deserves more widespread concern among the medical fraternities. The objective of this review is to outline the etiology, pathology findings, and management practices of SPG ...
A. Foead, A. Mathialagan, R. Varadarajan, M. Larvin   +3 more
semanticscholar   +1 more source

The impact of frailty syndrome on skeletal muscle histology: preventive effects of exercise

FEBS Open Bio, EarlyView.
Frailty syndrome exacerbates skeletal muscle degeneration via increased ECM deposition and myofiber loss. This study, using a murine model, demonstrates that endurance exercise attenuates these histopathological alterations, preserving muscle integrity. Findings support exercise as a viable strategy to counteract frailty‐induced musculoskeletal decline
Fujue Ji, Hae Sung Lee, Haesung Lee, Jong‐Hee Kim   +3 more
wiley   +1 more source

Symmetric Peripheral Gangrene Secondary to Sepsis

Journal of Clinical and Biomedical Sciences
Symmetrical peripheral gangrene (SPG) is described as rapid onset of peripheral and symmetrical gangrene in the lack of large vessel occlusive disease with high mortality rate.1 Hereby reporting an event of Upper limb symmetrical gangrene caused
Mohan Reddy K P Mani, S V Srinivasa
doaj   +1 more source