Results 101 to 110 of about 9,984 (253)

Extracellular matrix remodeling and immune reprogramming drive residual tumor progression of liver cancer after incomplete microwave ablation

Molecular Oncology, EarlyView.
Incomplete microwave ablation (iMWA) of liver cancer triggers a biphasic progression in residual tumors. At Day 3, the microenvironment is characterized by acute inflammatory responses and extracellular matrix (ECM) remodeling. By Day 14, a profound shift occurs toward oncogenic signal transduction and immunosuppression, marked by macrophage ...
Yu Liu, Yubei He, Nikolaus Berndt, Michael Mülleder, Kathrin Textoris‐Taube, Jing Guo, Matthias Stechele, Justus Ramtke, Shraga Nahum Goldberg, Lynn Jeanette Savic   +9 more
wiley   +1 more source

Fournier’s gangrene in the HIV era [PDF]

, 2015
Background: Fournier’s gangrene is a devastating condition that affects mostly patients whose immunity has been reduced. There is increasing evidence for increasing incidence of the disease in those with HIV disease.Objective: To evaluate the ...
Magoha, G, Nyaga, P, Ngugi, P
core   +1 more source

Cyclic azapeptide CD36 ligand attenuates cardiac injury and reduces long‐chain fatty acid accumulation after myocardial ischemia–reperfusion in mice

FEBS Open Bio, EarlyView.
In a murine model of myocardial ischemia and reperfusion (MI/R), the CD36 azapeptide ligand MPE‐298 reduces cardiac injury and transiently lowers left ventricular long‐chain fatty acids (LCFAs) accumulation 3 h after reperfusion, accompanied by a decrease of oxidative stress and inflammation‐associated genes' expression in the heart and adipose tissue.
Jade Gauvin, Naghme Radmannia, David N. Huynh, Liliane Ménard, Caroline Daneault, Maïté Veilleux, Ahsanullah Ahsanullah, André C. Carpentier, William D. Lubell, Matthieu Ruiz, Huy Ong, Sylvie Marleau, Simon‐Pierre Gravel   +12 more
wiley   +1 more source

Necrotising Soft-tissue Infection of the Breast: Case Series of a Rare but Fatal Entity [PDF]

International Journal of Anatomy Radiology and Surgery
Necrotising Soft-tissue Infection (NSTI) of the breast is an exceedingly rare but highly aggressive condition that constitutes a true surgical emergency.
Sabyasachi Hazra, Meghraj Kundan, Karan Barat, MS Hrishikesh, Aman Jawwad   +4 more
doaj   +1 more source

Concurrence of symmetrical peripheral gangrene and venous limb gangrene following polytrauma: a case report

, 2018
Background Symmetrical peripheral gangrene is characterized as acral (distal extremity) ischemic limb injury affecting two or more extremities, without large vessel obstruction, typically in a symmetrical fashion.
Jih Huei Tan, Mahazir Kassim, Chor Lip Henry Tan, Yuzaidi Mohamad, Theodore E. Warkentin   +4 more
core   +1 more source

Aquaporin‐3 and aquaporin‐5 impact the development of pancreatic ductal adenocarcinoma spheroids

FEBS Open Bio, EarlyView.
Schematic representation of the role of aquaporin‐3 (AQP3) and aquaporin‐5 (AQP5) in pancreatic ductal adenocarcinoma (PDAC). Both proteins are upregulated in PDAC and are associated with tumor progression and metastatic potential. Silencing AQP3 or AQP5 in PDAC spheroids results in decreased diameter, area, and overall growth, underscoring their key ...
Catarina Pimpão, Diogo M. Engrácia, Graça Soveral, Filipa Mendes   +3 more
wiley   +1 more source

Digital Gangrene and Postoperative Survival Following Lung or Heart–Lung Transplantation in Patients With Systemic Sclerosis

ACR Open Rheumatology
Objective Digital gangrene is a severe complication of systemic sclerosis (SSc). This study aimed to examine the incidence and clinical associations of digital gangrene in patients with SSc after lung or heart–lung transplantation. Methods We performed a
Brian S. Lee, Jason H. Melehani, Shufeng Li, Joshua Mooney, Lorinda Chung   +4 more
doaj   +1 more source

BACTERIAL PROFILE AND ANTIBIOTIC SUSCEPTIBILITY TEST AMONG DIABETES MELLITUS PATIENTS WITH GANGRENE IN SURABAYA

Journal of Vocational Health Studies
Background: Gangrene is a severe complication of damaged tissue that can occur in people with Diabetes Mellitus (DM), putting them at risk for bacterial infection. A pus culture can show diabetic gangrene patients' infecting bacteria.
Imro`atul Qona`ah, Aliyah Siti Sundari, Ratna Wahyuni, Dwi Wahyu Indriati   +3 more
doaj   +1 more source

Gangrene and perforation of the gallbladder as a complication of typhoid fever: A case report [PDF]

Scripta Medica
A rare consequence of typhoid illness is gall bladder gangrene with perforation. The gut and more rarely, the gall bladder are involved in surgical complications of typhoid fever.
Sarma Arnabjyoti Deva, Das Chinmoy, Sarma Pratap Chandra   +2 more
doaj   +1 more source

Fournier's Gangrene: outcome analysis at three tertiary hospitals in Harare Zimbabwe

, 2016
Background: Fournier’s gangrene is a potentially life threatening, infective necrotizing fasciitis of the external genitalia and perineum. The average world mortality rate is between 20 – 30%.
Meki, Shingirirai Christopher
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