Results 91 to 100 of about 9,984 (253)
Molecular Oncology, EarlyView.Tumour heterogeneity and clonal evolution of metastatic salivary gland cancer were evaluated in two patients with adenoid carcinoma and one patient with myoepithelial carcinoma. Radiology‐guided autopsy enabled multi‐region sampling (total samples n = 149), followed by whole‐genome sequencing and phylogenetic reconstruction (17 tumour samples, 4–7 per ...
Gerben Lassche +10 more
wiley +1 more source
Fournier\u27s gangrene mimicking an acute epididymitis.
, 2021 Fournier\u27s gangrene is a urologic emergency secondary to a necrotizing soft tissue infection. Fournier\u27s gangrene is characterized by severe pain and features of Fournier\u27s gangrene may include edema, blisters and bullae, crepitus, subcutaneous ...
Paige, Amy +4 more
core +1 more source
, 2013 Fournier's gangrene is a fulminant, necrotizing soft-tissue infection of the genital, perineal, and perianal regions. Fournier's isolated to the penis is a rare occurrence due the highly vascular nature of the penis.
Sorbellini, Maximiliano +3 more
core +1 more source
Molecular Oncology, EarlyView.This study identifies somatostatin receptor 4 (Sstr4) as a critical tumor suppressor against skin and head/neck cancers (HNSCC, cSCC, and BCC). The loss of Sstr4 removes a check on cell growth, causing hyperactivation of the MAPK‐ERK signaling pathway (↑).
Ali Taqvi +6 more
wiley +1 more source
Molecular Oncology, EarlyView.This study integrates publicly available transcriptomic datasets to identify molecular signatures associated with response to neoadjuvant chemoradiotherapy in locally advanced rectal cancer. By analyzing a combination of multiple cohorts with bioinformatics approaches, we reveal biological pathways and immune‐related features that may improve ...
Aleksandra Stanojevic +10 more
wiley +1 more source
Clinics and Practice, 2014 Thrombosis may play an important role in the pathophysiology of certain complications of sickle cell disease (SCD). While the association between SCD and ulcerative colitis (UC) is still debatable, inflammatory bowel disease is known to be associated ...
Angela E. Rankine-Mullings +3 more
doaj +1 more source
Fournier’s Gangrene: A 4-Year Retrospective Study in a Tertiary Academic Hospital [PDF]
Background: Fournier’s gangrene (FG) is a necrotizing fasciitis disease that affects the genital, perianal, and perineal regions. This study investigated the demography and treatment methods of patients with FG in a 4-year period in our hospital. Methods:
Almas Nur Prawoto +3 more
core +1 more source
Molecular Oncology, EarlyView.High‐risk bladder cancer is typically treated with Bacillus Calmette‐Guérin (BCG), but 30–40% of patients relapse. No FDA‐ or CE‐approved biomarkers currently predict or prognosticate BCG failure. We systematically reviewed the literature and identified 72 eligible studies, revealing several promising biomarkers associated with BCG treatment response ...
Rui Ribeiro‐Pereira +7 more
wiley +1 more source
Molecular Oncology, EarlyView.We established the avian chorioallantoic membrane (CAM) assay as a scalable in vivo model for studying circulating tumor cells (CTCs). Human gastrointestinal tumors spontaneously released genetically validated CTCs that were detected across multiple platforms, demonstrating that the CAM model provides an accessible tool for investigating early cancer ...
Dennis Roth +17 more
wiley +1 more source
Symmetrical peripheral gangrene in a child following severe malaria with concomitant sepsis
Nigerian Journal of PaediatricsSymmetrical peripheral gangrene (SPG) is a well- documented but rare clinical syndrome characterized by symmetrical distal ischemic damage leading to gangrene of two or more sites in the absence of large vessel obstruction or vasculitis. The aetiological
Katibi OS +3 more
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