Results 51 to 60 of about 102,320 (308)
Fierce Fusarium solani infection in diabetic foot – A double-barrel rifle
Journal of Current Research in Scientific MedicineDiabetic foot is one of the most serious and prevalent manifestations of diabetes mellitus. In a study conducted in Eastern India, 31.7% of diabetic patients with infections in the lower limb had positive fungal cultures.
Subha Kanthiah +3 more
doaj +1 more source
Autologous Platelet-rich Plasma in the Conservative Management of a Traumatic Foot Injury with Impending Gangrene in a Pregnant Patient: A Case Report [PDF]
Journal of Clinical and Diagnostic ResearchMusculoskeletal trauma during pregnancy presents a dual challenge, as both the maternal management and foetal safety should be balanced together. This condition presents a challenge in the use of ionising imaging, anaesthesia and operative fixation ...
Ansh Khanduja +3 more
doaj +1 more source
Clinical Case Reports, 2015 Key Clinical MessageFournier gangrene is a rapidly progressive necrotizing infection of the perineal and genital fascia, often polymicrobial. Severity is increased in older patients, diabetics and the immunocompromised. As in this case, the disease can have an indolent onset. Early recognition and aggressive treatment is important.
openaire +2 more sources
Prognostic factors in Fournier gangrene.
Asian Journal of Surgery, 2017 BACKGROUND Fournier gangrene is a necrotizing fasciitis, arising in the genital and perineal area. This entity is still associated with a high mortality rate despite improvements in antibiotic and surgical treatment.
J. Ruiz-Tovar, L. Córdoba, J. M. Devesa
semanticscholar +1 more source
Therapeutic Apheresis and Dialysis, EarlyView.ABSTRACT Background Chronic micro‐inflammation in patients with end‐stage renal disease (ESRD) is a significant driver of cardiovascular complications and diminished quality of life. While standard hemodialysis (SHD) effectively manages small‐molecule clearance, its ability to remove medium‐to‐large uremic toxins—the primary catalysts of systemic ...
Hongwei Zuo +5 more
wiley +1 more source
Microbiome‐blood–brain barrier interactions in aging — mechanisms and therapeutic potential
FEBS Letters, EarlyView.Aging reshapes the gut microbiome (↓SCFA‐producing commensals; ↑pro‐inflammatory outputs), shifting circulating metabolites (↓SCFAs; ↑LPS, ↑TMAO, ↑PAA) that act at the BBB to increase nonspecific transcytosis, alter transport, and promote astrocyte reactivity, heightening brain vulnerability.
Daniel Cuervo‐Zanatta +3 more
wiley +1 more source
Autoamputation of diabetic toe with dry gangrene: a myth or a fact?
Diabetes, Metabolic Syndrome and Obesity, 2018 Abdullah Al Wahbi Division of Vascular Surgery, King Abdulaziz Medical City, Riyadh, Saudi Arabia Abstract: Diabetes is associated with various complications and reduced quality of life. Of the many complications, some are life-threatening.
Al Wahbi A
doaj
Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation
FEBS Letters, EarlyView.Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang +2 more
wiley +1 more source
Acute Uterine Inversion Complicating Mid-Trimester Unsafe Abortion in a Teenage Nigerian Girl
Annals of Health Research, 2022 Uterine inversion is a rare but life-threatening obstetric emergency, complicating 1 in 2,000 to 1 in 50,000 deliveries. Very rarely, this condition also complicates unsafe abortion.
Nyeche S, Ubom AE
doaj +1 more source