Results 61 to 70 of about 102,320 (308)
Urology Case Reports, 2019 We report here a case of penile gangrene due to penile calciphylaxis in a patient with diabetes mellitus and chronic renal failure. Initially the patient demonstrated dry gangrene of the glans penis, which turned to wet after partial amputation. The main
V.R. Dunev, N.H. Kolev, P.P. Genov
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Liver organoids: modelling complexity in homeostasis and disease
FEBS Letters, EarlyView.Studying liver in vitro has been challenging because simple 2D cell cultures fail to capture liver's cellular and architectural complexity. To bridge this gap, scientists increasingly use organoids, 3D liver models which better mimic liver composition and function. This review examines recent advances in liver organoid complexity and realism, discusses
Anna M. Dowbaj, Meritxell Huch
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FEBS Letters, EarlyView.This review focuses on the role of autophagy and mitophagy in maintaining pancreatic β‐cell function and homeostasis. We discuss how genetic defects affecting these pathways contribute to the development of type 1, type 2, monogenic, and gestational diabetes. We further explore their potential as therapeutic targets. Created in BioRender.
Yunkyeong Lee +2 more
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Jornal Vascular BrasileiroResumo Contexto As amputações dos membros inferiores, sejam definidas como maiores ou menores, são um grave problema de saúde, com altos índices de morbimortalidade e de relevante impacto social. Diferentes características clínicas dos pacientes parecem
Seleno Glauber de Jesus-Silva +5 more
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Malrotation with Distal Duodenal Necrosis in a Neonate
Iranian Journal of Pediatric Surgery, 2020 Malrotation with midgut volvulus often results in gangrene of midgut with relative sparing of duodenum. An extremely unusual case of Malrotation with isolated necrosis of distal duodenum is described with brief review of literature.
Vinit kumar Thakur +5 more
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Translophagy—A potential link between autophagy impairment and translational errors
FEBS Letters, EarlyView.Neurodegenerative diseases are characterised by the accumulation of abnormal proteins and protein aggregates, but their origin often remains unknown. We propose that selective autophagy removes damaged protein‐making machinery, preventing errors during protein synthesis.
Mykola V. Korolchuk +11 more
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A curious case of black limb in tuberculosis
Journal of Global Infectious DiseasesWith a global burden of 10 million new cases per year, tuberculosis (TB) is a major health problem in developing countries like India, with an incidence of 2.69 million.
Pournami Balasundaran +4 more
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eJHaem, 2022 Blastic plasmacytoid dendritic cell neoplasm (BPDCN) is a rare and aggressive hematologic malignancy. It is associated with poor prognosis and heterogenous presentation. The CD123‐directed cytotoxin, Tagraxofusp, is a targeted therapy for BPDCN. Here, we
Jad Sibai +4 more
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Who are you, Doctor Bianchon? On Honoré de Balzac's illness and death Leonid I. Dvoretsky
Клинический разбор в общей медицине, 2021 The paper explores clinical manifestations and the course of the disease in Honoré Balzac, the famous French writer. Interpretation of possible causes and the disease treatment is analyzed.
Leonid I. Dvoretsky
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