Results 61 to 70 of about 2,233 (212)

Laparoscopic management of an axially torsed gangrenous Meckel′s diverticulum in a child

African Journal of Paediatric Surgery, 2016
Meckel′s diverticulum (MD) is the most common congenital anomaly of the gastrointestinal tract. Most often is asymptomatic but it may give a number of complications including gastrointestinal bleeding, obstruction and inflammation.
Kotti Ahmed, Zitouni Hayet, Louati Hamdi, Ben Dhaou Mahdi, Jallouli Mohamed, Mhiri Riadh   +5 more
doaj   +1 more source

Aquaporin‐3 and aquaporin‐5 impact the development of pancreatic ductal adenocarcinoma spheroids

FEBS Open Bio, EarlyView.
Schematic representation of the role of aquaporin‐3 (AQP3) and aquaporin‐5 (AQP5) in pancreatic ductal adenocarcinoma (PDAC). Both proteins are upregulated in PDAC and are associated with tumor progression and metastatic potential. Silencing AQP3 or AQP5 in PDAC spheroids results in decreased diameter, area, and overall growth, underscoring their key ...
Catarina Pimpão, Diogo M. Engrácia, Graça Soveral, Filipa Mendes   +3 more
wiley   +1 more source

Mycoplasma pneumoniae Infection and Progressive Cold Agglutinin Syndrome in a Child: Catastrophic Multiple Cutaneous Necrosis

Clinical Case Reports
Acrocyanosis and gangrene are rare but serious manifestations of CAS caused by MP infection in children. These symptoms may lead to severe complications if not managed appropriately, highlighting the need for clinicians to remain vigilant and provide ...
Bahareh Abtahi‐Naeini, Sharareh Babaei, Sayed Nassereddin Mostafavi, Mahsa Pourmahdi‐Boroujeni, Sara Adibfard   +4 more
doaj   +1 more source

Port Site Hernia after Laparoscopic Surgery: Incidence, Pathogenesis and Management Strategies [PDF]

Journal of Clinical and Diagnostic Research
Although Port Site Hernia (PSH) is a rare complication after laparoscopic surgery, with an incidence of 0.65-2.8%, it can be deadly due to the inherent risk of bowel strangulation. Various factors like trocar size, design, improper closure of the defect,
Vinayak Vishnupant Kshirsagar, Yogesh Bhupal Langade, Prabhat Bhaskarrao Nichkaode, Nilam Sandeep Memane, Rakesh Diliprao Kothavale   +4 more
doaj   +1 more source

Arteriosclerotic Gangrene

Anesthesia & Analgesia, 1943
The staff of a large community hospital caring predominantly for charity patients is continually faced with the problem of managing cases of gangrene of the toes and feet due to arteriosclerosis. More often than not the patient does not apply for aid until the condition is well established and he is in an advanced toxic condition, or even moribund. The
openaire   +2 more sources

From energy provision to protein synthesis: Tunnelling nanotubes as mediators of intercellular metabolic cooperation in cancer

FEBS Open Bio, EarlyView.
The cytoskeleton‐mediated transport of mitochondria via tunnelling nanotubes restores respiration, increases ATP production, rescues cells from apoptosis, activates the AKT/mTOR signalling pathway, promotes cell migration and invasiveness, contributes to cancer progression and treatment resistance.
Stanislava Martínková, Jan Trnka
wiley   +1 more source

Treatment with KCL‐286, a first‐in‐class retinoic acid receptor‐β (RARβ) agonist, ameliorates neuronal DNA damage and inflammation in a mouse model of Alzheimer's disease

FEBS Open Bio, EarlyView.
Repair of neuronal DNA damage in Alzheimer's disease by KCL‐286. (A) Amyloid‐β oligomers and plaques impair neuronal DNA repair pathways, leading to DNA double‐strand breaks and glial activation. (B) KCL‐286 activates RARβ/RXR signalling via retinoic acid response elements (RAREs), associated with increased BRCA1 expression, enhanced DNA repair and ...
Natasha Hill, Hassan Yousef Othman AlMuallim, Elouisa Maddock, Carl Hobbs, Earl Clarke, Maria B. Goncalves, Jonathan P. T. Corcoran   +6 more
wiley   +1 more source

Management of Fournier’s gangrene with skin grafting by bagging technique of testes: case report

GMS Interdisciplinary Plastic and Reconstructive Surgery DGPW, 2019
Aim: To share our experience with the management of Fournier gangrene (FG) using the bagging technique of the testes, and to highlight the importance of implementing a multidisciplinary approach in managing FG.
AlShehri, Yasir Ali, AlBurshaid, Hiba, AlBassam, Layan, AlMutairi, Khalid   +3 more
doaj   +1 more source

MagmaFlow: A desktop platform for artificial intelligence‐driven expression analysis

FEBS Open Bio, EarlyView.
MagmaFlow is a free, no‐code platform for gene expression analysis. It generates interactive volcano plots, links genes to literature, pathways, and diseases, prioritizes candidates using millions of publications, identifies affected biological processes, builds network diagrams, and exports publication‐ready figures and reports for macOS and Windows ...
Carlos E. Buss, Ao Li, Eduardo H. Gilglioni, Mayank Bansal, Sumeet Pal Singh, Latifa Bakiri, Alessandra K. Cardozo, Esteban N. Gurzov   +7 more
wiley   +1 more source

Malformin A1–mediated cytotoxicity in ovarian cancer cells occurs through pyroptosis and autophagy

FEBS Open Bio, EarlyView.
This study investigated the effects of the natural compound Malformin A1 (MA1) on the cytoskeleton that regulates cell proliferation and migration. Disruption of the cytoskeleton can impair these processes and promote cancer cell death. MA1 disrupted cytoskeletal organization, induced DNA damage, inflammation, activated autophagy, and pyroptosis ...
Nada Abdullah Hassan, Ikram A. Burney, Shika Hanif Malgundkar, Siva Ramamoorthy, Ressin Varghese, Mohamed A. Al‐Kindi, Hamad Al Riyami, Shadia Al Bahlani, Sergey Dobretsov, Syed Imran Hassan, Benjamin K. Tsang, Yahya Tamimi   +11 more
wiley   +1 more source