Results 61 to 70 of about 102,021 (351)

Fournier's gangrene in a patient on dapagliflozin treatment for type 2 diabetes

Journal of Diabetes, 2019
Sodium-glucose cotransporter 2 (SGLT2) inhibitors are novel agents in the treatment of type 2 diabetes (T2D) that act by inhibiting glucose reabsorption in the proximal renal tubule.
C. E. Onder, Koray Gursoy, Ş. Kuşkonmaz, Uğur Koçer, C. Çulha   +4 more
semanticscholar   +1 more source

RKIP overexpression reduces lung adenocarcinoma aggressiveness and sensitizes cells to EGFR‐targeted therapies

Molecular Oncology, EarlyView.
RKIP, a metastasis suppressor protein, modulates key oncogenic pathways in lung adenocarcinoma. In silico analyses linked low RKIP expression to poor survival. Functional studies revealed RKIP overexpression reduces tumor aggressiveness and enhances sensitivity to EGFR‐targeted therapies, while its loss promotes resistance.
Ana Raquel‐Cunha, Joana Pinheiro, Rui F. Marques, Patrícia Fontão, Diana Cardoso‐Carneiro, Adriana Mendes, Izabela N. F. Gomes, Ana Carolina Laus, Renato J. da Silva‐Oliveira, Rui Manuel Reis, Olga Martinho   +10 more
wiley   +1 more source

Fierce Fusarium solani infection in diabetic foot – A double-barrel rifle

Journal of Current Research in Scientific Medicine
Diabetic foot is one of the most serious and prevalent manifestations of diabetes mellitus. In a study conducted in Eastern India, 31.7% of diabetic patients with infections in the lower limb had positive fungal cultures.
Subha Kanthiah, Sonia Subramanian, Nagalakshmi Ranjan, Poongodi Santhana Kumarasamy   +3 more
doaj   +1 more source

Malrotation with Distal Duodenal Necrosis in a Neonate

Iranian Journal of Pediatric Surgery, 2020
Malrotation with midgut volvulus often results in gangrene of midgut with relative sparing of duodenum. An extremely unusual case of Malrotation with isolated necrosis of distal duodenum is described with brief review of literature.
Vinit kumar Thakur, Digamber Chaubey, Vijayendra Kumar, Ramdhani Yadav, Deepak Kumar, Sandip Kumar Rahul   +5 more
doaj   +1 more source

GANGRENE OF THE EAR. [PDF]

JAMA: The Journal of the American Medical Association, 1896
Gangrene affecting the ear is a very rare disease. It is mentioned in but three out of seven books on the ear, in my library. I have never seen a case in private practice, nor in my service at the various hospitals and dispensaries, until the following one appeared at my clinic at the Illinois Charitable Eye and Ear Infirmary: Jan. 8, 1896, George T.,
openaire   +2 more sources

Fournier's gangrene: a modern analysis of predictors of outcomes.

Translational Andrology and Urology, 2019
Background Fournier's gangrene (FG) is a rapidly progressing necrotizing fasciitis that carries a significant morbidity and mortality. The present study sought to identify the predisposing factors related to FG and validate the Fournier's Gangrene ...
J. Sparenborg, Jacob Brems, A. M. Wood, Jonathan Hwang, K. Venkatesan   +4 more
semanticscholar   +1 more source

YAP1::TFE3 mediates endothelial‐to‐mesenchymal plasticity in epithelioid hemangioendothelioma

Molecular Oncology, EarlyView.
The YAP1::TFE3 fusion protein drives endothelial‐to‐mesenchymal transition (EndMT) plasticity, resulting in the loss of endothelial characteristics and gain of mesenchymal‐like properties, including resistance to anoikis, increased migratory capacity, and loss of contact growth inhibition in endothelial cells.
Ant Murphy, Samuel Hartzler, Paula A. Vargas Carranza, Shyaman Jayasundara, Madison E. Yates, Nimod D. Janson, Bozhi Liu, Annaleigh Benton, Majid Kazemian, Jason A. Hanna   +9 more
wiley   +1 more source

Gangrene and perforation of the gallbladder as a complication of typhoid fever: A case report [PDF]

Scripta Medica
A rare consequence of typhoid illness is gall bladder gangrene with perforation. The gut and more rarely, the gall bladder are involved in surgical complications of typhoid fever.
Sarma Arnabjyoti Deva, Das Chinmoy, Sarma Pratap Chandra   +2 more
doaj   +1 more source

Fournier's Gangrene: 10-Year Experience of a Plastic Surgery and Burns Department at a Tertiary Hospital.

Acta Médica Portuguesa, 2019
INTRODUCTION Fournier gangrene is a polymicrobial life threatening infection of perineal subcutaneous soft tissues with its point of origin in urologic, colorectal or skin diseases. Although more frequent in elderly and men, it can affect all genders and
J. Louro, M. Albano, João Baltazar, M. Vaz, C. Diogo, S. Ramos, L. Cabral   +6 more
semanticscholar   +1 more source

Multi‐omic profiling of squamous cell lung cancer identifies metabolites and related genes associated with squamous cell carcinoma

Molecular Oncology, EarlyView.
Using multi‐omic characterization, we aimed to identify key regulators specific to squamous cell lung carcinoma (SqCC). SqCC‐specific differentially expressed genes were integrated with metabolics data. High expression of the creatine transporter SLC6A8, along with elevated creatine levels, appeared to be a distinct metabolic feature of SqCC.
Johan Staaf, Daniel Ehinger, Hans Brunnström, Mats Jönsson, Frida Rosengren, Marija Kotevska, Anna Karlsson, Mattias Aine, Christian Frezza, Maria Planck, Elsa Arbajian   +10 more
wiley   +1 more source