Results 271 to 280 of about 8,124,306 (331)

CDK11 inhibition induces cytoplasmic p21WAF1 splice variant by p53 stabilisation and SF3B1 inactivation

Molecular Oncology, EarlyView.
CDK11 inhibition stabilises the tumour suppressor p53 and triggers the production of an alternative p21WAF1 splice variant p21L, through the inactivation of the spliceosomal protein SF3B1. Unlike the canonical p21WAF1 protein, p21L is localised in the cytoplasm and has reduced cell cycle‐blocking activity.
Radovan Krejcir, Lukasz Arcimowicz, Lucia Martinkova, Vaclav Hrabal, Filip Zavadil Kokas, Tomas Henek, Martina Kucerikova, Ondrej Bonczek, Pavlina Zatloukalova, Lenka Hernychova, Philip J. Coates, Borivoj Vojtesek, David P. Lane   +12 more
wiley   +1 more source

Lattice Expansion Leads to the Renormalization of Bulk-State Valence Band Structure and Band Gap in Bi₂Se₃. [PDF]

J Phys Chem Lett
Dong J, Li T, Yu H, Xia S, Chen W, Wen B, Ren Z, Sun Z, Yang X, Zhou C.   +9 more
europepmc   +1 more source

Reduced vascular leakage correlates with breast carcinoma T regulatory cell infiltration but not with metastatic propensity

Molecular Oncology, EarlyView.
A mouse model for vascular normalization and a human breast cancer cohort were studied to understand the relationship between vascular leakage and tumor immune suppression. For this, endothelial and immune cell RNAseq, staining for vascular function, and immune cell profiling were employed.
Liqun He, Chiara Testini, Neda Hekmati, Altea Bonello, Aglaia Schiza, Emmanuel Nwadozi, Mia Phillipson, Carina Strell, Michael Welsh   +8 more
wiley   +1 more source

Observation of wave amplification and temporal topological state in a non-synthetic photonic time crystal. [PDF]

Nat Commun
Xiong J, Zhang X, Duan L, Wang J, Long Y, Hou H, Yu L, Zou L, Zhang B.   +8 more
europepmc   +1 more source

An Early Warning Marker in Acute Respiratory Failure: The Prognostic Significance of the PaCO₂-ETCO₂ Gap During Noninvasive Ventilation. [PDF]

Medicina (Kaunas)
Kırık S, Efgan MG, Bora ES, Tavşanoğlu U, Öz HÖ, Acar B, Yıldızlı S.   +6 more
europepmc   +1 more source

Plasma growth-associated protein 43 correlates with synaptic loss in Alzheimer's disease. [PDF]

Cell Rep Med
Lan G, Li B, Wang M, Barve A, Colin M, Buée L, Zhang L, Jiang M, Yang J, Li A, He Z, Zhou X, Zhu Y, Cai Y, Sun P, Liu L, Li J, Chen L, Fang L, Wang Y, Li M, Chen X, Shi D, Ye C, Fan X, Wang Q, Zhou L, Liu Z, Han Y, Wang L, Cheng G, Guan Y, Ni R, Richetin K, Xie F, Guo T.   +35 more
europepmc   +1 more source

A Low-Sidelobe Fully Metallic Ridge Gap Waveguide Antenna Array for W-Band Applications. [PDF]

Sensors (Basel)
Jiang H, Sheng L, Nie P, Feng Y, Wen J, Ji J, Cao W.   +6 more
europepmc   +1 more source

A Novel Ultrasound Assessment Technique of the Ulnar Collateral Ligament to Account for the Valgus Stress Effect of Gravity on the Medial Elbow. [PDF]

Orthop J Sports Med
Colberg RE, Vega TF, Towns J, Yates AF, Westbrooks B, Carlson S, Fleisig GS, Ithurburn MP.   +7 more
europepmc   +1 more source