Results 141 to 150 of about 25,607,358 (297)
Structure‐forward targeting of claudins with synthetic binders
FEBS Letters, EarlyView.Claudins form the paracellular barriers between epithelial and endothelial tissues at tight junctions and are targets for molecular binders with the goal of modulating barrier permeability. Claudin‐binding molecules are relevant in drug delivery or in altering claudin interactions with disease‐causing proteins.
Alex J. Vecchio
wiley +1 more source
The Early Career Gender Wage Gap [PDF]
In Finland the gender wage gap increases significantly during the first 10 years after labor market entry accounting most of the life-time increase in the gender wage gap.
Sami Napari
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FEBS Letters, EarlyView.Animals must match their growth rate to available nutrients. We show that in Drosophila larvae, the nutrient‐sensing TOR kinase controls growth by regulating levels of TFAM, a key regulator of mitochondrial function, in the adipose tissue. When nutrients are abundant, high TOR activity suppresses TFAM, lowering mitochondrial bioenergetic activity and ...
Shrivani Sriskanthadevan‐Pirahas +4 more
wiley +1 more source
Closing the Gap Clearinghouse annual report
, 2011 This report outlines the first year of operation and the significant achievements accomplished in that time. The Council of Australian Governments (COAG) has made a range of commitments to improve the lives of Indigenous Australians and in particular ...
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Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation
FEBS Letters, EarlyView.Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang +2 more
wiley +1 more source
Liver organoids: modelling complexity in homeostasis and disease
FEBS Letters, EarlyView.Studying liver in vitro has been challenging because simple 2D cell cultures fail to capture liver's cellular and architectural complexity. To bridge this gap, scientists increasingly use organoids, 3D liver models which better mimic liver composition and function. This review examines recent advances in liver organoid complexity and realism, discusses
Anna M. Dowbaj, Meritxell Huch
wiley +1 more source
Real time estimates of the euro area output gap: reliability and forecasting performance [PDF]
This paper provides evidence on the reliability of euro area real-time output gap estimates. A genuine real-time data set for the euro area is used, including vintages of several sets of euro area output gap estimates available from 1999 to 2006.
Musso, Alberto, Marcellino, Massimiliano
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The microbiome in human skin aging
FEBS Letters, EarlyView.Age‐related skin changes encompass the well‐known visible phenotypic alterations, together with microbiome dysbiosis and a series of molecular aging hallmarks. These hallmarks characterize not only a fully stablished aged phenotype but also the skin aging process itself.
Manuel Huerta Arana +3 more
wiley +1 more source
Eccentricity of Slow-Speed Salient-Pole Generator: Analysis based on Air Gap Spectrum
The air gap monitoring and fault diagnosis is exemplified for a slowspeed salient-pole generator of hydropower unit. Three types of measurements, namely, with contacting probes, non-contacting sensors and non-invasive sensors are discussed.
Elmanis-Helmanis, Rihards +1 more
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Close the Gap shadow report 2013
, 2013 In March 2008, the Australian Government and Opposition committed to the Close the Gap Campaign’s blueprint for closing the health equality gap between Aboriginal and Torres Strait Islander peoples and non-Indigenous Australians – the Close the Gap ...
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