Results 111 to 120 of about 5,034,726 (291)
Influenced by the local angle of attack of the air rudder, a complex separation and reattachment flow will form at the position of the full-motion rudder shaft thermal-protection ring during a hypersonic flight, accompanied by severe aerodynamic heating ...
Yibin DOU +6 more
doaj +1 more source
This review focuses on the role of autophagy and mitophagy in maintaining pancreatic β‐cell function and homeostasis. We discuss how genetic defects affecting these pathways contribute to the development of type 1, type 2, monogenic, and gestational diabetes. We further explore their potential as therapeutic targets. Created in BioRender.
Yunkyeong Lee +2 more
wiley +1 more source
The integration of axial flux motors into canned motor pumps offers a promising approach to overcome the efficiency and size limitations of traditional designs, particularly in critical sectors like aerospace.
Qiyuan Zhu, Yandong Gu, Junjie Bian
doaj +1 more source
Obesity raises blood levels of PAI‐1, a protein linked to metabolic dysfunction‐associated steatotic liver disease in people with obesity. In female mice fed a high‐fat diet, partially lowering PAI‐1 led to smaller subcutaneous fat cells and lower liver cholesterol, without changing body weight or insulin sensitivity.
Claudia E. Ramirez Bustamante +10 more
wiley +1 more source
Ligand‐dependent transcriptional heterogeneity in cell cycle gene expression delays G1/S entry
EGF and HRG induce distinct G1/S progression programs in ErbB2‐amplified BT474 breast cancer cells. Despite activating the potent ErbB2–ErbB3 heterodimer, HRG does not accelerate cell‐cycle entry. Instead, EGF promotes earlier restriction‐point passage via ERK–FOS signaling, whereas HRG activates the AKT–MYC axis, driving transcriptional heterogeneity ...
Ririn Rahmala Febri +5 more
wiley +1 more source
Emerging experimental and computational methods for studying redox‐regulated structural transitions
Redox reactions can reshape proteins and alter how they behave in cells, with important consequences for health and disease. This review explores emerging experimental and computational approaches for discovering these redox‐sensitive protein switches, revealing their structural effects, and predicting their behavior, opening new opportunities to ...
Tasneem Rass +2 more
wiley +1 more source
Séminaire GAP 'Savoirs et Idéologies en Politique' : Emmanuel Didier
SAVOIRS ET IDÉOLOGIES EN POLITIQUE Genèse, circulation, transmission Université Paris Ouest Nanterre — Plan du Campus Nous aurons le plaisir de recevoir le Mercredi 12 décembre 2012, 14h (Salle des Conférences, Bât F, 352) :Emmanuel Didier (GSPM,
gap
core
Synergistic perspectives—How single‐molecule biophysics complement biochemical understanding
In this review, we discuss how ensemble biochemistry and single‐molecule approaches are complementary, outline commonly used single‐molecule techniques, and illustrate their relevance through two representative case studies: chromatin organization by SMC complexes and pathway choice during DNA double‐strand break repair.
Sara De Bragança +2 more
wiley +1 more source
Université Paris Ouest Nanterre Séminaire du Groupe d’Analyse Politique Savoirs et idéologies en politique Genèse, circulation, transmission Responsables : Arnault SKORNICKI askornicki@yahoo.fr Laurent BONELLI laurent.bonelli@conflits.org Mercredi 18 mai
gap
core +1 more source
Analysis of fan-stage gap-flow data to inform simulation of fan broadband noise. [PDF]
Grace S, Gonzalez-Martino I, Casalino D.
europepmc +1 more source

