Liquid biopsy‐based diagnostic evaluation of hypermethylated CpG sites for ovarian cancer diagnosis
This schematic outlines the workflow from biomarker identification to duplex MethyLight assay validation for epithelial ovarian cancer diagnosis using cfDNA‐based liquid biopsy. Initial screening of hypermethylated CpG candidates (cg02957270, cg10061138 cg00480298, COL2A1) was performed in tissue using ARMS‐PCR, COBRA, qPCR and image analysis. Selected
Deepa Bisht +3 more
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An Idealized Model of Extrusome Ejection Through the Collapse of a Capsule. [PDF]
Harrison A +3 more
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Loss of proton‐sensing TDAG8 increases tumor progression in mouse models of colon cancer
Loss of the pH‐sensing receptor TDAG8 accelerates colorectal cancer progression in mice. Animals lacking TDAG8 expression had increased tumor growth, DNA damage, and recruitment of tumor‐associated immune cells, including macrophages, neutrophils, and monocytes.
Ermanno Malagola +11 more
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Neuroergonomic evaluation of risk-warning eHMI penetration rates in vehicle platoons: effects on pedestrians' mental workload, situation awareness, and gap acceptance. [PDF]
Yang F +7 more
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Single‐cell multi‐omics reveals epigenetic heterogeneity across therapy‐adaptive tumor states, including quiescent/dormant, drug‐tolerant persister, and EMT‐like phenotypes. By linking regulatory features with state‐associated biomarkers, these approaches inform biomarker‐guided therapeutic strategies for evolving tumors.
Hee Jung Kim +3 more
wiley +1 more source
Influence of Zinc Doping on the Morphological, Structural, and Optical Characteristics of Copper Oxide Thin Films Prepared Through Ultrasound Spray Pyrolysis. [PDF]
Ballardo Rodríguez IC +4 more
europepmc +1 more source
Copper-doped zinc oxide nanoparticles as efficient antimicrobial agents: bridging electronic properties with biological properties. [PDF]
Almadhhi SS +6 more
europepmc +1 more source
Sol-gel synthesis and comprehensive characterization of MgO nanostructures: structural, optical, and dielectric insights. [PDF]
AbdelAll N +5 more
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GAPS IN MAMMALIAN BODY SIZE DISTRIBUTIONS REEXAMINED
Ecology, 1999Holling suggested that discontinuities in the body size distributions among species of animals are a universal feature of terrestrial biomes. We compared the magnitudes of body size gaps of mammal communities of North America and Australia to those generated by a simple random null model.
Evan Siemann, James H. Brown
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