Results 111 to 120 of about 5,641,921 (211)
From mice to humans—divergent strategies for intestinal homeostasis and regeneration
Recent advances such as organoid genome editing, xenotransplantation, imaging, and whole‐genome sequencing have enabled direct studies of human intestinal stem cells (ISCs). These studies reveal species‐specific features, including slower ISC proliferation, distinct injury responses, slower somatic mutation accumulation in humans, and an inverse ...
Keiko Ishikawa +2 more
wiley +1 more source
cedric.plont@gmail.com Doctorant en Science Politique sous la direction de Bernard Lacroix (GAP) et Yves Déloye (CRPS) : « La construction de l’Etat, cérémonies royales et les bourgeois de Paris entre les XVIe et XVIIIe siècles : Emergence politique d’un
gap
core
GAP SS&H Newsletter (Vol 2 Issue 1)
GAP SS&H Newsletter Volume 2 Issue
GAP SSHRC
core +1 more source
Design and analysis strategies for robust microbiome ageing research
The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik +5 more
wiley +1 more source
Gap size effects on centrifugally and rotationally driven instabilities
International audienceThe rotation effects on centrifugally driven instabilities in curved channel flow with a finite gap are investigated. An inviscid criterion of stability is formulated to explain the behavior of the flow when rotation and curvature ...
Wesfreid, Eduardo +5 more
core +1 more source
Reconstructing enzyme evolution by protein engineering
Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler +2 more
wiley +1 more source
Gap Dependent Bifurcation Behavior of a Nano-Beam Subjected to a Nonlinear Electrostatic Pressure
This paper presents a study on the gap dependent bifurcation behavior of an electro statically-actuated nano-beam. The sizedependent behavior of the beam was taken into account by applying the couple stress theory.
Mohammad Fathalilou +2 more
doaj +1 more source
Investigating transcription factor dynamics in health and disease using FRAP
FRAP analysis of GFP‐tagged transcription factors reveals how molecular mobility and target engagement change in response to drug treatment. By combining live‐cell imaging, quantitative model fitting, and statistical analysis, this approach uncovers transcription factor dynamics linked to disease mechanisms, providing a powerful framework for ...
Kannan Govindaraj +3 more
wiley +1 more source
Heterogeneity gap in stable juridiction structures [PDF]
Stability, Jurisdictions, Public Projects, Heterogeneity ...
Sholmo, WEBER +3 more
core
Conserved binding mode but diverse interfaces of MreC‐PBP2 interactions
The crystal structure of abMreC reveals a conserved two β‐barrel architecture and provides structural insights into its role within the bacterial elongasome. The abMreC–abPBP2 complex model identifies the molecular basis of MreC‐mediated PBP2 recognition, contributing to the regulation of peptidoglycan synthesis.
Hyunseok Jang +4 more
wiley +1 more source

