Results 111 to 120 of about 1,332,853 (314)

Spatiotemporal and quantitative analyses of phosphoinositides – fluorescent probe—and mass spectrometry‐based approaches

open access: yesFEBS Letters, EarlyView.
Fluorescent probes allow dynamic visualization of phosphoinositides in living cells (left), whereas mass spectrometry provides high‐sensitivity, isomer‐resolved quantitation (right). Their synergistic use captures complementary aspects of lipid signaling. This review illustrates how these approaches reveal the spatiotemporal regulation and quantitative
Hiroaki Kajiho   +3 more
wiley   +1 more source

Alternative Measures of Homeownership Gaps Across Segregated Neighboorhoods [PDF]

open access: yes
The dramatic rise in the U.S. homeownership rate from 64% in 1996 to almost 70% in 2005 has prompted increased attention to the relation between homeownership and demographic characteristics of households.
Paul Carrillo, Anthony Yezer
core  

Phosphatidylinositol 4‐kinase as a target of pathogens—friend or foe?

open access: yesFEBS Letters, EarlyView.
This graphical summary illustrates the roles of phosphatidylinositol 4‐kinases (PI4Ks). PI4Ks regulate key cellular processes and can be hijacked by pathogens, such as viruses, bacteria and parasites, to support their intracellular replication. Their dual role as essential host enzymes and pathogen cofactors makes them promising drug targets.
Ana C. Mendes   +3 more
wiley   +1 more source

The Ground Effect and the Mirror Effect in small air gaps

open access: yes, 2006
In the present paper we investigate the Ground Effect of small rod-rod air gaps, in connection to the Mirror Effect of rod-plate air gaps. The Ground Effect is a phenomenon, which is observed due to the fact that in air gap arrangements one of the two ...
Maglara, S   +3 more
core  

Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation

open access: yesFEBS Letters, EarlyView.
Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe   +3 more
wiley   +1 more source

Structural instability impairs function of the UDP‐xylose synthase 1 Ile181Asn variant associated with short‐stature genetic syndrome in humans

open access: yesFEBS Letters, EarlyView.
The Ile181Asn variant of human UDP‐xylose synthase (hUXS1), associated with a short‐stature genetic syndrome, has previously been reported as inactive. Our findings demonstrate that Ile181Asn‐hUXS1 retains catalytic activity similar to the wild‐type but exhibits reduced stability, a looser oligomeric state, and an increased tendency to precipitate ...
Tuo Li   +2 more
wiley   +1 more source

Independent review into gender pay gaps in medicine in England [PDF]

open access: yes, 2020
Report setting out the findings from the independent review into gender pay gaps in medicine in England. The independent review into gender pay gaps in medicine in England was commissioned by the Department of Health and Social Care in 2017.
Williams, Mark   +7 more
core  

The (Glg)ABCs of cyanobacteria: modelling of glycogen synthesis and functional divergence of glycogen synthases in Synechocystis sp. PCC 6803

open access: yesFEBS Letters, EarlyView.
We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee   +3 more
wiley   +1 more source

Monk’s tonsure-like gaps in the tussock grass Spartina argentinensis (Gramineae)

open access: yesRevista de Biología Tropical, 2001
Monk's tonsure-like gaps develop inside gramineans and other plants. The tonsures of Spartina argentinensis originate as a result of tussock development and disturbance.
J. P. Lewis   +2 more
doaj  

Refining Spatial and Temporal XCO2 Characteristics Observed by Orbiting Carbon Observatory-2 and Orbiting Carbon Observatory-3 Using Sentinel-5P Tropospheric Monitoring Instrument NO2 Observations in China

open access: yesRemote Sensing
The spatial and temporal variations in the atmospheric CO2 concentrations evidently respond to anthropogenic CO2 emission activities. NO2, a pollutant gas emitted from fossil fuel combustion, comes from the same emission sources as CO2.
Kaiyuan Guo   +4 more
doaj   +1 more source

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