Results 11 to 20 of about 2,000 (98)

Corrigendum: Gardasil^® as adjunctive therapy for respiratory papillomatosis at Red Cross Children's Hospital, Cape Town. [PDF]

J Coll Med S Afr
No abstract available.
Frank S, McGuire JK, Kabagenyi F, Pretorius V, Peer S.   +4 more
europepmc   +2 more sources

AS04 drives superior cross-protective antibody response by increased NOTCH signaling of dendritic cells and proliferation of memory B cells. [PDF]

Front Immunol
IntroductionThe Gardasil-4® vaccine targets HPV types 6, 11, 16 and 18 and is formulated with amorphous alum. Cervarix® targets HPV types 16 and 18 using AS04 (Al(OH)3 + TLR4 agonist MPL) to enhance immune response.
D'Onofrio V, Santana AC, Pauwels M, Waerlop G, Willems A, De Boever F, Müller M, Sehr P, Waterboer T, Leroux-Roels I, Sharma AA, Sékaly RP, Leroux-Roels G.   +12 more
europepmc   +2 more sources

Relationship between Humoral Immune Responses against HPV16, HPV18, HPV31 and HPV45 in 12-15 Year Old Girls Receiving Cervarix® or Gardasil® Vaccine. [PDF]

PLoS One, 2015
BackgroundHuman papillomavirus (HPV) vaccines confer protection against the oncogenic genotypes HPV16 and HPV18 through the generation of type-specific neutralizing antibodies raised against virus-like particles (VLP) representing these genotypes.
Godi A, Bissett SL, Miller E, Beddows S.
europepmc   +2 more sources

<i>Chlamydia trachomatis</i> Infection and Its Association with Human Papillomavirus Among Adolescent Girls and Young Women of Eastern Cape, South Africa. [PDF]

Epidemiologia (Basel)
Background/Objectives: Adolescent girls and young women (AGYW) have a high burden of sexually transmitted infections (STIs). This study examined the prevalence of Chlamydia trachomatis, its association with human papillomavirus (HPV), and other ...
Akapo OO, Mbulawa ZZA.
europepmc   +2 more sources

Syndemic Synergy of HPV, HIV, and HSV-2 for Oncogenic HPV Replication in Female Sex Workers. [PDF]

Trop Med Infect Dis
Background: Female sex workers (FSWs) in sub-Saharan Africa bear a disproportionate burden of sexually transmitted infections, including HIV, high-risk HPV (HR-HPV), and herpes simplex virus type 2 (HSV-2).
Muwonga Tukisadila J, Mboumba Bouassa RS, Tonen-Wolyec S, Loemba H, Muwonga J, Belec L.   +5 more
europepmc   +2 more sources

Prophylactic vaccines against HPV-caused cervical cancer: novel vaccines are still demanded. [PDF]

Infect Agent Cancer
Several high-risk types of human papillomaviruses (HPVs) are associated with cervical cancer and other malignancies. Despite the tremendous success of marketed prophylactic HPV vaccines for the past 18 years, cervical cancer remains a significant global ...
Amiri S, Rasekh S, Moezzi SMI, Seifi N, Fatemi SA, Fathi S, Bagheri A, Negahdaripour M.   +7 more
europepmc   +2 more sources

A Preclinical Immunogenicity Study of the Recombinant Human Papillomavirus Nine-Valent Virus-like Particle Vaccine. [PDF]

Vaccines (Basel)
Background: Cervical cancer is associated with persistent infection of high-risk human papillomaviruses (HPVs). Prophylactic HPV vaccines have been recommended and have significant efficacy in preventing cervical cancer.
Xu D, Li JD, An J, Ma XX, Wang XL, Zhou Z, Liu HP, Diao MJ, Jiang YX, Zhou LY, Tong X, Zhou CL.   +11 more
europepmc   +2 more sources

The use of the HPV vaccine in a group of primarily unvaccinated HPV-positive patients. [PDF]

Hum Vaccin Immunother
Background: Human papillomavirus (HPV) infection remains the most prevalent sexually transmitted viral infection worldwide and a major etiologic factor for cervical and other anogenital cancers.
Pruski D, Millert-Kalińska S, Żurawski J, Jach R, Przybylski M.   +4 more
europepmc   +2 more sources

Memory B-cells elicited by different HPV vaccine regimens in the DoRIS randomised controlled trial. [PDF]

NPJ Vaccines
Prophylactic human papillomavirus vaccines such as Cervarix® and Gardasil®9 induce robust and sustained antibody responses over time. One driver of such responses is memory B-cells (MBCs), primed during initial HPV-vaccine exposure.
Wiggins R, Baisley KJ, Indangasi J, Changalucha J, Ashwin H, Brown N, Whitworth HS, Joakim D, Mayaud P, Hashim R, Maxwell C, Mutani P, Kamala B, Lowe B, Pinto L, Kemp T, deSanjosé S, Kapiga S, Hayes RJ, Watson-Jones D, Lacey CJ.   +20 more
europepmc   +2 more sources

High human papillomavirus (HPV)-35 prevalence among South African women with cervical intraepithelial neoplasia warrants attention.

PLoS ONE, 2022
Human papillomavirus (HPV) prevalence and genotype distribution data is important for HPV vaccine monitoring. This study investigated the prevalence and distribution of HPV genotypes in cervical lesions of unvaccinated women referred to Nelson Mandela ...
Zizipho Z A Mbulawa, Keletso Phohlo, Mirta Garcia-Jardon, Anna-Lise Williamson, Charles B Businge   +4 more
doaj   +2 more sources