Results 51 to 60 of about 377,889 (137)

Superstitions on Human Papillomavirus in Africa: A Scoping Review

open access: yesPublic Health Challenges, Volume 5, Issue 2, June 2026.
Africa bears a high burden of HPV‐induced diseases; this scoping review explored how superstitions and cultural beliefs fuel vaccine hesitancy. There are widespread myths and opposition from cultural/religious leaders that drive HPV vaccine hesitancy; targeted and culturally sensitive campaigns/educations are essential to improve vaccine uptake and ...
Jimoh Amzat   +6 more
wiley   +1 more source

Expanded strain coverage for a highly successful public health tool: Prophylactic 9-valent human papillomavirus vaccine

open access: yesHuman Vaccines & Immunotherapeutics, 2017
Human papillomavirus is considered the causative factor for cervical cancer, which accounts for approximately 5% of the global cancer burden and more than 600,000 new cases annually that are attributable to HPV infection worldwide.
Zhigang Zhang   +3 more
doaj   +1 more source

The evolving role of structural biology in pharma: integration of X‐ray crystallography, cryo‐electron microscopy and beyond

open access: yesActa Crystallographica Section D, Volume 82, Issue 6, Page 587-602, June 2026.
This review describes how an integrated structural biology platform at Merck Sharp & Dohme LLC, Rahway, New Jersey, USA, combining X‐ray crystallography, cryo‐EM, MicroED and cryo‐ET, enables seamless three‐dimensional insights from molecular to cellular length scales.
Jill E. Chrencik   +44 more
wiley   +1 more source

Relationship between HPV-specific vaccine antibodies in sera and genital samples. [PDF]

open access: yes, 2013
(A) Neutralization titers were normalized to IgG levels in serum and genital samples for HPV16 (left panel; Cervarix® n = 21, Gardasil® n = 28) and HPV18 (right panel; Cervarix® n = 21, Gardasil® n = 26).
Rebecca Howell-Jones (408906)   +8 more
core   +1 more source

Behavioral abnormalities in female mice following administration of aluminum adjuvants and the human papillomavirus (HPV) vaccine Gardasil [PDF]

open access: yes, 2020
Vaccine adjuvants and vaccines may induce autoimmune and inflammatory manifestations in susceptible individuals. To date most human vaccine trials utilize aluminum (Al) adjuvants as placebos despite much evidence showing that Al in vaccine-relevant ...
Weiss R.   +8 more
core   +1 more source

Unraveling the enigma: elucidating the relationship between the physicochemical properties of aluminium-based adjuvants and their immunological mechanisms of action

open access: yesAllergy, Asthma & Clinical Immunology, 2018
Aluminium salts are by far the most commonly used adjuvants in vaccines. There are only two aluminium salts which are used in clinically-approved vaccines, Alhydrogel® and AdjuPhos®, while the novel aluminium adjuvant used in Gardasil® is a sulphated ...
Emma Shardlow   +2 more
doaj   +1 more source

Fel d 1‐Expressing Plant‐Derived Bioparticle: A Novel Treatment for Cat Allergy

open access: yesAllergy, Volume 81, Issue 6, Page 2156-2171, June 2026.
This study investigates the allergenicity and immunogenicity profile of a novel plant‐derived Fel d 1 bioparticle (eBP). Fel d 1 eBP promotes immune tolerance by redirecting allergic Th2 responses toward Th1 and IL‐10–producing regulatory pathways, including Bregs.
Janice A. Layhadi   +16 more
wiley   +1 more source

Merck: Pricing Gardasil [PDF]

open access: yes, 2017
Allison Watkins, senior director of Merck's Vaccines Division, needed to decide on the pricing of Gardasil, Merck's newest vaccine and one of the company's most important product launches of the year.
Tim Calkins, Megha Vora
core   +1 more source

Human papillomavirus: Role of HPV2 and HPV9 in reducing the burden of cervical cancer in sub-Saharan Africa

open access: yesInternational Journal of Infectious Diseases
Cervical cancer remains a leading cause of death among women in sub-Saharan Africa, accounting for nearly a quarter of global deaths from this disease. Its high incidence is due to the high prevalence of HIV, the persistence of human papillomavirus (HPV)
Christian Tague   +10 more
doaj   +1 more source

MODERN ASPECTS OF HUMAN PAPILLOMAVIRUS VACCINATION

open access: yesБезопасность и риск фармакотерапии, 2018
Human papillomavirus refers to DNA-containing viruses and infects the skin and mucosal epithelium. One common way is to change the  expression of cellular genes by integrating the viral genome into  cellular DNA.
O. S. Alyautdina, M. A. Darmostukova
doaj   +1 more source

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