Gardnerella species exhibit synergy in their ability to displace Lactobacillus crispatus adhered to HeLa cells [PDF]
PeerJBackground Bacterial vaginosis (BV) is the most common vaginal infection in reproductive-age women. It is associated with adverse pregnancy complications, such as preterm birth and low birth weight, in addition to an increased risk of acquisition of HIV ...
Ângela Lima +3 more
doaj +5 more sources
Bacterial Load of Gardnerella spp. and Fannyhessea vaginae and Its Association with Cervicovaginal Inflammatory Cytokine Responses Across Vaginal Microbiota Patterns [PDF]
MicroorganismsBacterial vaginosis (BV) is a common vaginal dysbiosis characterized by the depletion of Lactobacillus species and the overgrowth of facultative anaerobic bacteria, particularly Gardnerella spp. and Fannyhessea vaginae. The vaginal microbiota plays a key
Laura Emi Yonezawa +8 more
doaj +4 more sources
A generalist lifestyle allows rare Gardnerella spp. to persist at low levels in the vaginal microbiome [PDF]
Microbial Ecology, 2020 Abstract Gardnerella spp. are considered a hallmark of bacterial vaginosis, a dysbiosis of the vaginal microbiome. There are four cpn60 sequence-based subgroups within the genus (A, B, C, and D), and thirteen genome species have been defined recently.
Salahuddin Khan +2 more
europepmc +5 more sources
Slipped strand mispairing in the gene encoding sialidase NanH3 in Gardnerella spp [PDF]
Infection and Immunity, 2020 Abstract Cell wall proteins with sialidase activity are involved in carbohydrate assimilation, adhesion to mucosal surfaces, and biofilm formation. Gardnerella spp. inhabit the human vaginal microbiome and encode up to three sialidase enzymes, two of which are suspected to be cell ...
Shakya P. Kurukulasuriya +2 more
openaire +4 more sources
Transport and Utilization of Glycogen Breakdown Products by Gardnerella spp. from the Human Vaginal Microbiome [PDF]
Microbiology Spectrum, 2022 Increased abundance of Gardnerella spp. is a diagnostic characteristic of bacterial vaginosis, an imbalance in the human vaginal microbiome associated with troubling symptoms and negative reproductive health outcomes, including increased transmission of sexually transmitted infections and ...
Pashupati Bhandari, Janet E. Hill
openaire +3 more sources
Characterization of an α-Glucosidase Enzyme Conserved in Gardnerella spp. Isolated from the Human Vaginal Microbiome [PDF]
Journal of Bacteriology, 2020 Increased abundance of Gardnerella spp. is a diagnostic characteristic of bacterial vaginosis, an imbalance in the human vaginal microbiome associated with troubling symptoms, and negative reproductive health outcomes, including increased transmission of sexually transmitted infections and ...
Pashupati Bhandari +4 more
openaire +4 more sources
Sequence Comparison of Vaginolysin from Different Gardnerella Species
Pathogens, 2021 Gardnerella vaginalis has recently been split into 13 distinct species. In this study, we tested the hypotheses that species-specific variations in the vaginolysin (VLY) amino acid sequence could influence the interaction between the toxin and vaginal ...
Erin M. Garcia +5 more
doaj +2 more sources
Type II Restriction-Modification System from Gardnerella vaginalis ATCC 14018
Pathogens, 2020 Intensive horizontal gene transfer may generate diversity and heterogeneity within the genus Gardnerella. Restriction-modification (R-M) systems and CRISPR-Cas are the principal defense tools against foreign DNA in bacteria.
Aistė Bulavaitė +3 more
doaj +2 more sources
Pathogens, 2021 The description of Gardnerella vaginalis was recently updated and three new species, including nine genome species within Gardnerella, were defined using whole genome sequences and matrix assisted laser desorption ionization time of flight (MALDI-TOF ...
Aistė Bulavaitė +2 more
doaj +2 more sources
Bacterial Infections Role in Gynecological Cancers Development: Narrative Review. [PDF]
Cancer Rep (Hoboken)ABSTRACT Background Gynecological cancers are among the most common cancers in women that affect female reproductive organs. The most common gynecological cancers are ovarian, cervical, uterine/endometrial, vaginal, and vulvar cancer. Women's reproductive organs have a dynamic and relative microbial balance.
Azargun R +7 more
europepmc +2 more sources