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Advances in Research on the Relationship Between Vaginal Microbiota and Adverse Pregnancy Outcomes and Gynecological Diseases

Microorganisms, 2023
The human microbiota inhabiting different parts of the body has been shown to have a significant impact on human health, with the gut microbiota being the most extensively studied in relation to disease.
Chunmei Ying, Xianyang Hu, Fuju Zhao
exaly   +4 more sources

Determinants of Vaginal Microbiota Composition [PDF]

Frontiers in Cellular and Infection Microbiology, 2020
There is increasing evidence that the composition of a woman's vaginal microbiota significantly influences her sexual and reproductive health, including her risk of miscarriage, preterm birth, HIV and other sexually transmitted infections.
Douglas S Kwon, Túlio de Oliveira, Yumna Moosa   +2 more
exaly   +5 more sources

Healthy Vaginal Microbiota and Influence of Probiotics Across the Female Life Span

Frontiers in Microbiology, 2022
Vaginal microbiota plays a central role in women’s health and reproduction. Vaginal microbiota is dynamic and shaped by hormonal shifts in each stage of a woman’s life from pre-puberty to postmenopause.
Johanna Maukonen
exaly   +3 more sources

Potential Role of Vaginal Microbiota in Ovarian Cancer Carcinogenesis, Progression and Treatment

Pharmaceutics, 2023
Ovarian cancer represents one of the most challenging gynecologic cancers which still has numerous unknowns on the underlying pathogenesis. In addition to the verified contributors such as genomic predisposition and medical history in the carcinogenesis,
Tingtao Chen, Zhaoxia Liu, Xiumiao Zhao
exaly   +3 more sources

The profiles of vaginal microbiota in fertile and infertile Thai women [PDF]

BMC Women's Health
Background Vaginal microbiota dysbiosis has been associated with female reproductive health and infertility. This study aimed to compare vaginal microbiota profiles according to fertility and ovarian induction status among Thai women.
Jiayu Li, Thunnapas Apinuthirunchot, Surasith Chaithongwongwatthana, Prangwalai Chanchaem, Vorthon Sawaswong, Rungrat Jitvaropas, Sunchai Payungporn, Harnam Kaur, Unnop Jaisamrarn   +8 more
doaj   +2 more sources

Association between vaginal microbiota in early pregnancy and gestational diabetes mellitus: a nested case-control study [PDF]

BMC Microbiology
Background To investigate the association between vaginal microbiota structure in early pregnancy and gestational diabetes mellitus (GDM) and to characterize microbial signatures for early screening for GDM.
Xiang Hong, Mengjie Zhao, Furong Tan, Hanyue Zheng, Xiaoling Ding, Jiechen Yin, Xuening Zhang, Bei Wang   +7 more
doaj   +2 more sources

The Vaginal Microbiota of Pregnant Women Varies with Gestational Age, Maternal Age, and Parity

Microbiology Spectrum, 2023
The composition of the vaginal microbiota is heavily influenced by pregnancy and may factor into pregnancy complications, including spontaneous preterm birth.
Roberto Romero, Kevin R. Theis, Nardhy Gomez-Lopez, Andrew D. Winters, Jonathan J. Panzer, Huang Lin, Jose Galaz, Jonathan M. Greenberg, Zachary Shaffer, David J. Kracht, Tinnakorn Chaiworapongsa, Eunjung Jung, Francesca Gotsch, Jacques Ravel, Shyamal D. Peddada, Adi L. Tarca   +15 more
doaj   +1 more source

Identification of shared bacterial strains in the vaginal microbiota of related and unrelated reproductive-age mothers and daughters using genome-resolved metagenomics

PLoS ONE, 2022
It has been suggested that the human microbiome might be vertically transmitted from mother to offspring and that early colonizers may play a critical role in development of the immune system.
Michael T. France, Sarah E. Brown, Anne M. Rompalo, Rebecca M. Brotman, Jacques Ravel   +4 more
doaj   +2 more sources

Role of the human vaginal microbiota in the regulation of inflammation and sexually transmitted infection acquisition: Contribution of the non-human primate model to a better understanding?

Frontiers in Reproductive Health, 2022
The human vaginal microbiota has a central role in the regulation of the female reproductive tract (FRT) inflammation. Indeed, on one hand an optimal environment leading to a protection against sexually transmitted infections (STI) is associated with a ...
Cindy Adapen, Louis Réot, Elisabeth Menu, Elisabeth Menu   +3 more
doaj   +1 more source

Large-scale characterisation of the pregnancy vaginal microbiome and sialidase activity in a low-risk Chinese population

npj Biofilms and Microbiomes, 2021
Vaginal microbiota-host interactions are linked to preterm birth (PTB), which continues to be the primary cause of global childhood mortality. Due to population size, the majority of PTB occurs in Asia, yet there have been few studies of the pregnancy ...
Sherrianne Ng, Muxuan Chen, Samit Kundu, Xuefei Wang, Zuyi Zhou, Zhongdaixi Zheng, Wei Qing, Huafang Sheng, Yan Wang, Yan He, Phillip R. Bennett, David A. MacIntyre, Hongwei Zhou   +12 more
doaj   +1 more source