Results 31 to 40 of about 40,493 (241)

Vaginal Microbiota and Mucosal Pharmacokinetics of Tenofovir in Healthy Women Using a 90-Day Tenofovir/Levonorgestrel Vaginal Ring

Frontiers in Cellular and Infection Microbiology, 2022
BackgroundA relationship between the vaginal microbiota and tenofovir (TFV) concentrations and activity after topical administration has been previously reported.ObjectiveCONRAD A15-138 was a randomized, placebo-controlled Phase I study aimed at ...
Andrea R. Thurman, Jacques Ravel, Pawel Gajer, Mark A. Marzinke, Louise A. Ouattara, Terry Jacot, M. Melissa Peet, Meredith R. Clark, Gustavo F. Doncel   +8 more
doaj   +1 more source

Vaginal microbiota and susceptibility to HIV [PDF]

AIDS, 2018
: Bacterial vaginosis, characterized by the replacement of the Lactobacillus-dominant microbiota with anaerobic bacteria and facultative Gram-negative rods, has been associated with adverse reproductive health outcomes including HIV acquisition. With the advent of newer molecular techniques, the vaginal microbiota can be investigated in more detail and
McKenna C, Eastment, R Scott, McClelland
openaire   +2 more sources

Maternal Bacterial Engraftment in Multiple Body Sites of Cesarean Section Born Neonates after Vaginal Seeding—a Randomized Controlled Trial

mBio, 2023
Children delivered by elective, prelabor Cesarean section (C-section) are not exposed to the birth canal microbiota and, in relation to vaginally delivered children, show altered microbiota development.
Noel T. Mueller, Moira K. Differding, Haipeng Sun, Jincheng Wang, Shira Levy, Varsha Deopujari, Lawrence J. Appel, Martin J. Blaser, Tanima Kundu, Ankit A. Shah, Maria Gloria Dominguez Bello, Suchitra K. Hourigan   +11 more
doaj   +1 more source

Species composition and dynamic changes of vaginal microbiota in patients with recurrent vulvovaginal candidiasis [PDF]

Xin yixue, 2022
Objective To investigate the species composition and dynamic changes of vaginal microbiota in patients with recurrent vulvovaginal candidiasis （RVVC）. Methods Six patients with confirmed symptomatic RVVC were enrolled in this study.
Ou Liying, Zhou Chenfei, Cai Huihua, Liu Mubiao
doaj   +1 more source

Diversity of cervical microbiota in asymptomatic chlamydia trachomatis genital infection: a pilot study [PDF]

, 2017
Chlamydia trachomatis genital infection continues to be an important public health problem worldwide due to its increasing incidence. C. trachomatis infection can lead to severe sequelae, such as pelvic inflammatory disease, obstructive infertility, and ...
DI PIETRO, Marisa, Farcomeni, Alessio, Filardo, Simone, Latino, Maria A, Porpora, Maria Grazia, Recine, Nadia, Sessa, Rosa   +6 more
core   +3 more sources

Vaginal Acidity Affects Vaginal Microbiota in Postmenopausal Women

The Indonesian Biomedical Journal, 2022
BACKGROUND: The changes in vaginal acidity impact the composition of the vaginal microbiota, either commensal or pathogenic. After menopause, the vaginal tract is more susceptible to infection. Current study was conducted to analyze the effect of vaginal acidity changes on the vaginal microbiota composition in menopausal women.METHODS: A cross ...
Juminten Saimin, Yenti Purnamasari, Sufiah Asri Mulyawati, Nur Indah Purnamasari, Arimaswati Arimaswati, Ferry Sandra   +5 more
openaire   +2 more sources

The Vaginal Microbiota, Bacterial Biofilms and Polymeric Drug-Releasing Vaginal Rings [PDF]

Pharmaceutics, 2021
The diversity and dynamics of the microbial species populating the human vagina are increasingly understood to play a pivotal role in vaginal health. However, our knowledge about the potential interactions between the vaginal microbiota and vaginally administered drug delivery systems is still rather limited.
Louise Carson, Ruth Merkatz, Elena Martinelli, Peter Boyd, Bruce Variano, Teresa Sallent, Robert Karl Malcolm   +6 more
openaire   +5 more sources

Role of lactobacilli and lactoferrin in the mucosal cervicovaginal defense [PDF]

, 2018
Human lactoferrin is an iron-binding glycoprotein present at high concentrations in breast milk and colostrum. It is produced by many exocrine glands and widely distributed in a variety of body fluids.
Aagaard, Abramov, Agerberth, Aldunate, Alexander, Allsworth, Anahtar, Ando, Appelmelk, Aroutcheva, Ashida, Baker, Baranger, Beigi, Berlutti, Berlutti, Berlutti, Bradshaw, Bradshaw, Britigan, Brooks, Brotman, Bullen, Byrne, Caccavo, Cauci, Cherpes, Cole, Cole, Conti, Corbin, Corbishley, Cutone, Cutone, De Gregorio, Deese, Delgado-Rizo, Drannik, Elass, Ericksen, Eschenbach, Eslami, Frioni, Fritsch, Gajer, He, He, Hearps, Hedges, Hein, Hemalatha, Hickey, Hiemstra, Hill, Hill, Hudić, Hummelen, Jakobsson, Judd, Kaushic, Kelver, Klebanoff, Kohlhoff, Kościuczuk, Lamont, Larsen, Legrand, Legrand, Leitch, Maggi, Marrazzo, Martin, Martin, Mastromarino, Mastromarino, Mastromarino, Meijerink, Michieli, Moberg, Morrison, Morrison, Nardis, Ness, Niyonsaba, Olmsted, Olmsted, Omata, Ong, O’Hanlon, Paesano, Paesano, Paesano, Paesano, Paesano, Pazgier, Peipert, Peipert, Petrova, Pino, Puddu, Quayle, Rampersauda, Raulston, Ravel, Ravel, Redondo-Lopez, Reghunathan, Rizzo, Rizzo, Roberton, Rosa, Rönnqvist, Santiago, Santiago, Sarkar, Sessa, Shakibaei, Shust, Singh, Singh, Spadaro, Spear, Spurbeck, Srinivasan, Srinivasan, Stallmann, Straub, Stríz, Suzuki, Tachedjian, Teng, Teng, Teng, Tuyama, Valenti, Valenti, Valenti, Valore, Van de Wijgert, Vargas-Villavicencio, Vielfort, Vitali, Walther-António, Ward, Weinberg, Wiesenfeld, Wiesner, Wilson, Wilson, Wilson, Wira, Wira, Wira, Wira, Wu, Yamamoto, Zhou   +156 more
core   +2 more sources

Association Between Vaginal Bacterial Microbiota and Vaginal Yeast Colonization

The Journal of Infectious Diseases, 2020
Abstract Background Vaginal yeast is frequently found with Lactobacillus-dominant microbiota. The relationship between vaginal yeast and other bacteria has not been well characterized. Methods These analyses utilized data from the ...
McKenna C, Eastment, Jennifer E, Balkus, Barbra A, Richardson, Sujatha, Srinivasan, Joshua, Kimani, Omu, Anzala, Jane, Schwebke, Tina L, Fiedler, David N, Fredricks, R Scott, McClelland   +9 more
openaire   +3 more sources

Recent insights into the vaginal microbiota

Microbiota in Health and Disease, 2022
Research on the vaginal microbiome and its relation to women’s health has steadily gained momentum in recent years. Traditionally, vaginal microbiome studies have focused on the pathogenesis of various diseases. Recent publications focus more on health and support a key role for Lactobacillus species and their dominance in maintaining a healthy state ...
Condori, S., Ahannach, S., Vander Donck, L., Oerlemans, E., Dillen, J., Dricot, C., Gehrmann, T., Spacova, I., Lebeer, S.   +8 more
openaire   +1 more source