Results 301 to 310 of about 678,239 (344)

Bio‐Based Castor Oil Derivatives Synthesized From 2‐Hydroxypropyl Ricinoleate and Ricinoleic Ethanolamide for Wood Coating Applications

open access: yesAdvanced Sustainable Systems, EarlyView.
Castor oil is a biobased molecule with a high natural carbon content and modifiable hydroxyl functional groups. This article describes the synthesis, characterization, and application of the novel reactive compounds for coating applications Abstract This work presents the synthesis of two molecules, methacrylated 2‐hydroxypropyl ricinoleate (2‐HPR MMA)
Vojtěch Jašek   +7 more
wiley   +1 more source

Exploring Functionally Enhanced BLP‐Trained Macrophage Subpopulations in S. Aureus Infection: Underlying Mechanisms and Therapeutic Significance

open access: yesAdvanced Science, EarlyView.
BLP‐trained macrophages show augmented resistance to infection, but their mechanisms remain unclear. scRNA‐seq identified 13 BMDM subsets, with two novel anti‐inflammatory/antibacterial subpopulations (C5/C7) emerging post‐BLP training. BLP training activates NRF2, attenuates oxidative stress/ferroptosis, and boosts glycolysis/OXPHOS. Adoptive transfer
Yantong Wan   +13 more
wiley   +1 more source

NNMT Orchestrates Metabolic‐Epigenetic Reprogramming to Drive Macrophage‐Myofibroblast Transition in Hypertrophic Scarring

open access: yesAdvanced Science, EarlyView.
In macrophage‐myofibroblast transition, upregulated NNMT depletes S‐Adenosylmethionine‌ (SAM) and nicotinamide adenine dinucleotide(NAD+), thereby triggering epigenetic reprogramming via Histone H3 Lysine 27 acetylation (H3K27ac) accumulation at the promoter region of master transcription factor Prrx1.
Xiwen Dong   +11 more
wiley   +1 more source

Efficient Light Harvesting and Water Retention Realized by Soybean Protein‐Based Microgels Embedded in Hybrid Sodium Alginate Hydrogels Containing Photocatalyst for Hydrogen Evolution

open access: yesAdvanced Science, EarlyView.
By incorporating SPN/SA microgels into SA hydrogels containing g‐C3N4/Pt nanosheets, highly efficient light absorption and superior water retention are achieved, thereby significantly enhancing hydrogen evolution efficiency. This is because microgels act as light scattering centers, enabling effective scattering of incident light and improving light ...
Jie Yu   +6 more
wiley   +1 more source

Elevated Apolipoprotein E Expression in Hippocampal Microglia Drives Temporal Lobe Epilepsy Progression

open access: yesAdvanced Science, EarlyView.
In temporal lobe epilepsy, hippocampal APOE is markedly upregulated predominantly in microglia. APOE overexpression in microglia drives TLR4 and cGAS/STING‐dependent neuroinflammation, engages bidirectional crosstalk with neurons and astrocytes, increases neuronal excitability, and perturbs hippocampal lipid metabolism. These findings suggest that APOE‐
Jianwei Shi   +10 more
wiley   +1 more source

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