Results 101 to 110 of about 145,241 (196)

Discovery, Herbicidal Activity and Biosynthesis of a Novel Natural Tetramic Acid from Alternaria Species

open access: yesAdvanced Science, EarlyView.
The biosynthetic mechanism of novel natural tetramic acid S‐TeA in Alternaria alternata is elucidated. Threonine acts as a precursor for 2‐amino‐3‐methylhexanoic acid (AMHA) synthesis via eight key enzymes from the branched‐chain amino acid biosynthetic pathway in the mitochondrion, wherein three unique enzymes (IPMS, IPMDH, and ISMD) play critical ...
He Wang   +9 more
wiley   +1 more source

Shape‐Selective Molecular Separations Enabled by Rigid and Interconnected Confinements Engineered in Conjugated Microporous Polymer Membranes

open access: yesAdvanced Science, EarlyView.
Conjugated microporous polymer membranes with narrowly distributed network pores are prepared by diffusion‐modulated electropolymerization. This approach precisely controls the monomer diffusion and coupling processes, regulating the crosslinking degree to prevent broad aggregate pores and microporous defects.
Yanqiu Lu   +4 more
wiley   +1 more source

Exercise without Weight Loss Prevents Seasonal Decline in Vitamin D Metabolites: The VitaDEx Randomized Controlled Trial

open access: yesAdvanced Science, EarlyView.
In people with overweight or obesity, regular exercise even without weight loss or vitamin D supplementation completely prevents the usual winter decline in the vitamin D metabolite that maintains health at a cellular level, 1,25(OH)2D3, and ameliorates the decline in the vitamin D status marker 25(OH)D.
Oliver J. Perkin   +11 more
wiley   +1 more source

MTFR2‐Mediated Fission Drives Fatty Acid and Mitochondrial Co‐Transfer from Hepatic Stellate Cells to Tumor Cells Fueling Oncogenesis

open access: yesAdvanced Science, EarlyView.
In the tumor margin of hepatocellular carcinoma (HCC), activated hepatic stellate cells upregulate MTFR2, initiating inhibiting DRP1 degradation and mitochondrial fission. This enhances mitochondrial availability and facilitates FAs synthesis via ACC1. Additionally, fission promotes RAC1‐mediated cytoskeletal remodeling and Miro1‐mediated mitochondrial
La Zhang   +9 more
wiley   +1 more source

Anion Exchange Membrane Seawater Electrolysis at 1.0 A cm−2 With an Anode Catalyst Stable for 9000 H

open access: yesAdvanced Science, EarlyView.
The CAPist‐S1 catalyst containing dense interlayer structure is synthesized by one‐step autologous method. The dense NiFe LDH interlayer inhibits the Cl− ions penetration onto metal substrate, significantly improving the corrosion resistance. The obtained catalyst requires an overpotential of 220 mV at 1.0 A cm−2 and exhibits excellent durability over ...
Jian Du   +6 more
wiley   +1 more source

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