Results 261 to 270 of about 4,191,571 (369)

Recent Advances in mRNA Delivery Systems for Cancer Therapy

Advanced Science, EarlyView.
This review systematically investigates the applications of mRNA therapy in cancer treatment, with particular emphasis on nonviral delivery systems, targeting strategies, stimulus‐responsive systems, and local delivery methods. Concluding with a meticulous evaluation, the review sheds light on the prevailing challenges while illuminating promising ...
Zheng Zhang, Ya‐Nan Fan, Si‐Qi Jiang, Ya‐Jing Ma, Yao‐Ru Yu, Yu‐Xin Qing, Qian‐Ru Li, Yi‐Lin Liu, Song Shen, Jun Wang   +9 more
wiley   +1 more source

Gas Chromatography/Mass Spectrometry Chemical Profiling of Volatile Compounds from Cranberry Plant Byproducts as Potential Antibacterials, Antifungals, and Antioxidants. [PDF]

Molecules
Aborah M, Scarano F, Neto C.
europepmc   +1 more source

Fish Swim Bladder‐Derived ECM Hydrogels Effectively Treat Myocardial Ischemic Injury through Immunomodulation and Angiogenesis

Advanced Science, EarlyView.
A unique hydrogel based on extracellular matrix from fish swim bladder, which is suitable for transcatheter delivery and possesses remarkable reparative capabilities for treating heart failure, is developed. It emerges as a multi‐effect factor profoundly influencing inflammation regulation, angiogenesis, and myocardial metabolism.
Yulong Fu, Canran Gao, Hailing Zhang, Jing Liu, Boxuan Li, Wei Chen, Xiuping Chen, Xue Lin, Ligang Fang, Zhihong Wang   +9 more
wiley   +1 more source

Serum metabolomics signature of maternally inherited diabetes and deafness by gas chromatography-time of flight mass spectrometry. [PDF]

J Diabetes Investig
Cao B, Lu H, Liu P, Zhang Y, Wang C.
europepmc   +1 more source

Hybrid Series of Carbon‐Vacancy Electrodes for Multi Chemical Vapors Diagnosis Using a Residual Multi‐Task Model

Advanced Science, EarlyView.
This study presents a graphene oxide‐based gas sensor array integrated with a deep learning framework for precise detection and classification of multiple gases. By combining advanced sensing materials and a 1D‐ResNet architecture, the system achieves high sensitivity and accuracy, demonstrating its potential for real‐time environmental monitoring ...
Tianci Liu, Yun Ji Hwang, Lu Zhang, Jongwoo Hong, Teajong Hwang, Seong Chan Jun   +5 more
wiley   +1 more source

Characterization of the aromatic profile of Ruché wine from Piedmont (Italy) with gas chromatography-mass spectrometry and unsupervised machine learning techniques. [PDF]

J Sci Food Agric
Orecchio C, Rabezzana R, Vincenti M, Bonometti E, Laurenti E, Operti L, Rigoletto M.   +6 more
europepmc   +1 more source

Identification of CD38high Monocyte as a Candidate Diagnostic Biomarker and Therapeutic Target for Sepsis

Advanced Science, EarlyView.
This study uncovers that CD38high monocytes discriminate sepsis and sterile inflammation and are associated with 28‐day mortality in bacterial sepsis. Targeting CD38 therapy reduces inflammatory response in monocytes and in sepsis mice model. Mechanistically, CD38‐HIF‐1α/glycolysis/MGO loop exacerbates sepsis‐induced immune dysregulation.
Ning Hua, Limin Kong, Li Fan, Yanan Bai, Yujun Zhou, Yanfang Zhang, Qingwei Zhao, Xiaoyang Lu, Hongyu Yang, Hangyang Li, Peili Ding, Yuyu Nan, Qinghua Ji, Ping Yang, Lu Li, Yijing Xin, Lijuan Zhao, Wei Yang, Wenqiao Yu, Saiping Jiang   +19 more
wiley   +1 more source

Manifestation of relativistic effects in the chemical properties of nihonium and moscovium revealed by gas chromatography studies. [PDF]

Front Chem
Yakushev A, Khuyagbaatar J, Düllmann CE, Block M, Cantemir RA, Cox DM, Dietzel D, Giacoppo F, Hrabar Y, Iliaš M, Jäger E, Krier J, Krupp D, Kurz N, Lens L, Löchner S, Mokry C, Mošať P, Pershina V, Raeder S, Rudolph D, Runke J, Sarmiento LG, Schausten B, Scherer U, Thörle-Pospiech P, Trautmann N, Wegrzecki M, Wieczorek P.   +28 more
europepmc   +1 more source

Bimetallic Ca/Zn Nanoagonist Remould the Immunosuppressive Hepatocellular Carcinoma Microenvironment Following Incomplete Microwave Ablation via Pyroptosis and the STING Signaling Pathway

Advanced Science, EarlyView.
The multifunctional bimetallic Ca/Zn nanoagonist (PZH/Zn@CaNA) significantly downregulated the JAK2‐STAT3 signaling pathway, which effectively inhibited the proliferation and growth of HCC with incomplete microwave ablation. Furthermore, the released bimetallic ions (Ca2⁺ and Zn2⁺) synergistically enhanced oxidative stress‐mediated cytotoxicity ...
Yuan Ling, Xiayi Liang, Kangning Yan, Guichun Zeng, Xiaoqi Zhu, Jinghang Jiang, Shaolong Lu, Xiaobo Wang, Yuying Zhou, Zhaoshen Li, Wei Mai, Duo Wang, Jie Chen   +12 more
wiley   +1 more source

Multidimensional-Constrained Suspect Screening of Hydrophobic Contaminants Using Gas Chromatography-Atmospheric Pressure Chemical Ionization-Ion Mobility-Mass Spectrometry. [PDF]

Anal Chem
Shi X, Sobek A, Benskin JP.
europepmc   +1 more source