Results 31 to 40 of about 4,191,571 (369)

In vivo evidence for glycyl radical insertion into a catalytically inactive variant of pyruvate formate‐lyase

open access: yesFEBS Letters, EarlyView.
Dimeric pyruvate formate‐lyase cleaves pyruvate using a radical‐based mechanism. G734 serves as a radical storage location, and the radical is transferred to the catalytic C419 residue. Mutation of the C418‐C419 pair causes loss of enzyme activity, but does not impede radical introduction onto G734. Therefore, cis‐ but not trans‐radical transfer occurs
Michelle Kammel   +2 more
wiley   +1 more source

Gas chromatography of volatile organic compounds [PDF]

open access: yes, 1973
System has been used for problems such as analysis of volatile metabolities in human blood and urine, analysis of air pollutants, and in tobacco smoke chemistry.
Zlatkis, A.
core   +1 more source

Comparison of phenolic and volatile profiles of edible and toxic forms of Detarium senegalense J. F. GMEL [PDF]

open access: yes, 2016
In Senegal, Detarium senegalense J.F. Gmel. (ditax in Wolof) is one of the most important important forest fruit species. However, exploitation of the edible fruit is based on local people's knowledge.
Boudard, Frédéric   +7 more
core   +2 more sources

Wave Mathematical Model to Describe Gas Chromatography

open access: yesHolodilʹnaâ Tehnika i Tehnologiâ, 2017
This paper describes the mathematical model of concentration waves passing through a layer of adsorbent. The analytic solution to this model deduced for eigenwaves of adsorptive layer had been found.
M. B. Kravchenko
doaj   +1 more source

Metal-Organic Frameworks Characterization via Inverse Pulse Gas Chromatography

open access: yesApplied Sciences, 2021
The desire to customize the properties of a material through complete control over both its chemical and architectural structure has created a constant and persistent need for efficient and convenient characterization techniques.
Kareem Yusuf   +3 more
doaj   +1 more source

ShcD adaptor protein drives invasion of triple negative breast cancer cells by aberrant activation of EGFR signaling

open access: yesMolecular Oncology, EarlyView.
We identified adaptor protein ShcD as upregulated in triple‐negative breast cancer and found its expression to be correlated with reduced patient survival and increased invasion in cell models. Using a proteomic screen, we identified novel ShcD binding partners involved in EGFR signaling pathways.
Hayley R. Lau   +11 more
wiley   +1 more source

Identifying metabolites by integrating metabolome databases with mass spectrometry cheminformatics. [PDF]

open access: yes, 2018
Novel metabolites distinct from canonical pathways can be identified through the integration of three cheminformatics tools: BinVestigate, which queries the BinBase gas chromatography-mass spectrometry (GC-MS) metabolome database to match unknowns with ...
A El-Tayeb   +45 more
core   +1 more source

Determination of ADP/ATP translocase isoform ratios in malignancy and cellular senescence

open access: yesMolecular Oncology, EarlyView.
The individual functions of three isoforms exchanging ADP and ATP (ADP/ATP translocases; ANTs) on the mitochondrial membrane remain unclear. We developed a method for quantitatively differentiating highly similar human ANT1, ANT2, and ANT3 using parallel reaction monitoring. This method allowed us to assess changes in translocase levels during cellular
Zuzana Liblova   +18 more
wiley   +1 more source

Characterization of aroma-active compounds in three Chinese Moutai liquors by gas chromatography-olfactometry, gas chromatography-mass spectrometry and sensory evaluation

open access: yesNatural Product Research, 2017
The aroma-active compounds in three Chinese Moutai liquors, aged 1 year, 15 years and 30 years were investigated in this study. The aroma compounds were analysed by gas chromatography–olfactometry (GC–O) coupled with gas chromatography–mass spectrometry (
Yunwei Niu   +4 more
semanticscholar   +1 more source

Iron‐dependent lysosomal LDL oxidation induces the expression of scavenger receptor A in human THP‐1 monocytes

open access: yesFEBS Open Bio, EarlyView.
In human monocytic cells THP‐1, a limited uptake of native—not oxidized—LDL/VLDL induced expression of scavenger receptor A and cellular adhesion. Induction was inhibited by lysosomotropic (WR‐1065) and lipophilic (BHT) antioxidants and by siRNAs against ferritinophagy.
Martina Čierna   +4 more
wiley   +1 more source

Home - About - Disclaimer - Privacy