Results 41 to 50 of about 237,789 (260)

Developmental programmes drive cellular plasticity, disease progression and therapy resistance in lung adenocarcinoma

open access: yesMolecular Oncology, EarlyView.
This study shows that lung adenocarcinomas exploit developmental branching morphogenesis to acquire a therapy resistant basal‐like tumour cell state. This process was found to be regulated by combined TP53 loss‐of‐function and type‐I interferon signalling, identifying a novel axis for biomarker and therapeutic target discovery.
Kamila J Bienkowska   +13 more
wiley   +1 more source

Design and Experiment of Low-Pressure Gas Supply System for Dual Fuel Engine

open access: yesPolish Maritime Research, 2020
A low-pressure gas supply system for dual fuel engines was designed to transport liquid natural gas from a storage tank to a dual fuel engine and gasify it during transportation.
Gu Xiaoyong   +3 more
doaj   +1 more source

Effect of Gas Exchange Interval on CH4 Recovery Efficiency and Study of Mechanism of CH4 Hydrate Replacement by CO2 Mixture

open access: yesFrontiers in Energy Research, 2021
As an environment-friendly natural gas hydrate exploitation method, CO2 replacement method can not only achieve the purpose of mining natural gas hydrate, but also store the current greenhouse gas CO2 in the form of hydrate on the seabed, and maintain ...
Ya-Long Ding, Hua-Qin Wang, Tao Lv
doaj   +1 more source

Loss of proton‐sensing TDAG8 increases tumor progression in mouse models of colon cancer

open access: yesMolecular Oncology, EarlyView.
Loss of the pH‐sensing receptor TDAG8 accelerates colorectal cancer progression in mice. Animals lacking TDAG8 expression had increased tumor growth, DNA damage, and recruitment of tumor‐associated immune cells, including macrophages, neutrophils, and monocytes.
Ermanno Malagola   +11 more
wiley   +1 more source

Fully Resolved Computational (CFD) and Experimental Analysis of Pressure Drop and Blood Gas Transport in a Hollow Fibre Membrane Oxygenator Module

open access: yesChemical Engineering Transactions, 2019
Membrane oxygenators or artificial lungs have become a reliable and live saving clinical technique. To limit side effects on blood platelet parameters the high extrinsic surface introduced by the hollow fiber membrane packing has to be decreased.
Michael Harasek   +11 more
doaj   +1 more source

A new flow chip in combination with multiphoton microscopy as a protocol for longitudinal 3D imaging of tissue calcification under shear stress

open access: yesFEBS Open Bio, EarlyView.
Miniaturized flow chip platform enabling continuous perfusion and longitudinal multiphoton 3D imaging of vascular smooth muscle cell constructs under physiological flow. Brightfield imaging guides region selection, while CellTracker Green and mRuby‐labeled fetuin‐A visualize cells and mineral deposition, respectively. Magnesium supplementation markedly
Vytautas Kučikas   +6 more
wiley   +1 more source

Mechanochemical Synthesis and Characterization of Nanostructured ErB4 and NdB4 Rare‐Earth Tetraborides

open access: yesAdvanced Engineering Materials, Volume 27, Issue 6, March 2025.
ErB4 and NdB4 nanostructured powders are produced by mechanochemical synthesis. 5 h mechanical alloying and 4 M HCl acid leaching are used in the production. ErB4 and NdB4 powders exhibit maximum magnetization of 0.4726 emu g−1 accompanied with an antiferromagnetic‐to‐paramagnetic phase transition at about TN = 18 K and 0.132 emu g−1 with a maximum at ...
Burçak Boztemur   +5 more
wiley   +1 more source

Design of a Real-Time Gas-Exchange Measurement System for Crop Stands in Environmental Scenarios

open access: yesAgronomy, 2020
In contrast to conducting measurements on single plants, canopy gas exchange monitored continuously and for large batches of plants can give high-value data for crop physiological models.
Hans-Peter Kläring, Oliver Körner
doaj   +1 more source

Innovative Processing of Compacted Waste Aluminum Alloy Powders via Controlled Remelting and Solidification

open access: yesAdvanced Engineering Materials, EarlyView.
This study demonstrates an efficient recycling route for out‐of‐spec AlSi10Mg atomized powders through compaction and arc remelting followed by suction casting. By correlating compaction load, cooling rate, and resulting microstructure, we show that intermediate pressures (50–80 kN) and rapid cooling refine dendrites, reduce porosity, and enhance ...
Mila Christy de Oliveira   +4 more
wiley   +1 more source

Machine learning predicts lung recruitment in acute respiratory distress syndrome using single lung CT scan

open access: yesAnnals of Intensive Care, 2023
Background To develop and validate classifier models that could be used to identify patients with a high percentage of potentially recruitable lung from readily available clinical data and from single CT scan quantitative analysis at intensive care unit ...
Francesca Pennati   +6 more
doaj   +1 more source

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