Immunization with the C-domain of α-toxin prevents lethal infection, localizes tissue injury, and promotes host response to challenge with Clostridium perfringens [PDF]
, 2013 © 2004 by the Infectious Diseases Society of America. All rights reserved.Clostridium perfringens gas gangrene is characterized by rapid tissue destruction, impaired host response, and, often, death. Phospholipase C (α-toxin) is the virulence factor most
Bayer, Clifford R. +5 more
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Radiological diagnosis of gas gangrene in a fetus at term
Taiwanese Journal of Obstetrics & Gynecology, 2016 Objective: To report a case of gas gangrene in a fetus at term, which was diagnosed by antenatal computed tomography (CT) imaging. Case Report: A 23-year-old primiparous woman, who did not undergo any prenatal health checks until term, developed ...
Kanako Abe +5 more
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The VirS/VirR two-component system regulates the anaerobic cytotoxicity, intestinal pathogenicity, and enterotoxemic lethality of Clostridium perfringens type C isolate CN3685. [PDF]
, 2011 Clostridium perfringens vegetative cells cause both histotoxic infections (e.g., gas gangrene) and diseases originating in the intestines (e.g., hemorrhagic necrotizing enteritis or lethal enterotoxemia).
Ma, Menglin +4 more
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Gas gangrene following implant removal after the union of a tibial plateau fracture: a case report
BMC Musculoskeletal Disorders, 2018 Background Gas gangrene is an invasive, fatal anaerobic infection that is characterized by acute, rapid evolution and high mortality. Gas gangrene is often secondary to open fractures with deep wounds but is extremely rare in the patients undergoing ...
Shanxi Wang, Lei Liu
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Mechanisms of Action and Cell Death Associated with Clostridium perfringens Toxins. [PDF]
, 2018 Clostridium perfringens uses its large arsenal of protein toxins to produce histotoxic, neurologic and intestinal infections in humans and animals. The major toxins involved in diseases are alpha (CPA), beta (CPB), epsilon (ETX), iota (ITX), enterotoxin (
McClane, Bruce A +2 more
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Rethinking our understanding of the pathogenesis of necrotic enteritis in chickens [PDF]
, 2009 For decades, low doses of antibiotics have been used widely in animal production to promote growth. However, there is a trend to reduce this use of antibiotics in feedstuffs, and legislation is now in place in Europe to prohibit their use in this way. As
Van Immerseel, Filip +3 more
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Intestinal perforation after surgical treatment for incisional hernia. iatrogenic or idiopathic? [PDF]
, 2018 Intestinal perforation (IP) is a life-threatening gastroenterological condition requiring urgent surgical care, which may present itself as an uncommon complication following incisional hernia repair surgery, most often because of iatrogenic traumatism ...
Amorosi, V +5 more
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Treatment of Gas Gangrene [PDF]
BMJ, 1944 The case-fatality rate of gas gangren? in the present war has been approximately 50%. Even with the low incidence found in desert warfare the disease accounts for a considerable pro portion of the deaths from wounds (Pulvertaft, 1943 ; Wiles, 1944), and becomes a more serious problem when the incidence rises, as it is already known to have risen, with ...
J. D. MacLennan, M. G. Macfarlane
openaire +3 more sources
Frontiers in Cellular and Infection Microbiology, 2023 Neutrophil extracellular traps (NETs) are networks of DNA and various microbicidal proteins released to kill invading microorganisms and prevent their dissemination.
Lisa Badilla-Vargas +6 more
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