Results 41 to 50 of about 4,895,720 (245)

Extracellular matrix remodeling and immune reprogramming drive residual tumor progression of liver cancer after incomplete microwave ablation

Molecular Oncology, EarlyView.
Incomplete microwave ablation (iMWA) of liver cancer triggers a biphasic progression in residual tumors. At Day 3, the microenvironment is characterized by acute inflammatory responses and extracellular matrix (ECM) remodeling. By Day 14, a profound shift occurs toward oncogenic signal transduction and immunosuppression, marked by macrophage ...
Yu Liu, Yubei He, Nikolaus Berndt, Michael Mülleder, Kathrin Textoris‐Taube, Jing Guo, Matthias Stechele, Justus Ramtke, Shraga Nahum Goldberg, Lynn Jeanette Savic   +9 more
wiley   +1 more source

Hysteresis Characteristics of Rocks Influenced by Rough Interfaces: A Discrete Element Method Study

Applied Sciences
Interfaces at multiple scales within rocks critically control the mechanical properties of rock masses. However, the mechanisms by which interface roughness characteristics affect non-plastic deformation remain incompletely understood.
Fukun Xiao, Daohua Yang, Jiaqin Guo, Kai Xie, Lei Shan   +4 more
doaj   +1 more source

Study on pressure relief effect in gob-side coal body under the influence of mining

Meikuang Anquan, 2021
By means of multi-field coupling numerical simulation and field measurement, the pressure relief effect and burst elimination range of side coal gas in goaf caused by inclined coal mining are analyzed.
ZHOU Ruoqian, WANG Hongtu, SHU Cai, CHU Tao
doaj   +1 more source

Single‐molecule DNA flow‐stretch assays for high‐throughput DNA–protein interaction studies

FEBS Open Bio, EarlyView.
We describe an optimised single‐molecule DNA flow‐stretch assay that visualises DNA–protein interactions in real time. Linear DNA fragments are tethered to a surface and stretched by buffer flow for fluorescence imaging. Using λ and φX174 DNA, this protocol enhances reproducibility and accessibility, providing a versatile approach for studying diverse ...
Ayush Kumar Ganguli, Mohammad Nour Alsamsam, Ugnė Bagdonaitė, Van Truc Vu, Chun‐Jen Huang, Polina Kuzhir, Mindaugas Zaremba, Aurimas Kopūstas, Marijonas Tutkus   +8 more
wiley   +1 more source

Effect of Sandstone Pore Morphology on Mechanics, Acoustic Emission, and Energy Evolution

Buildings
Roadway section form is an important part of the underground engineering structure, and it directly affects the overall stability of the roadway and the occurrence of underground disasters in coal mines. Based on this, this paper adopts a TYJ-500 electro-
Gang Liu, Dongwei Wang, Shengxuan Wang, Yonglong Zan, Qiqi Zhang, Zhitao Yang, Jiazhen Li, Zhen Wei   +7 more
doaj   +1 more source

Distinct Effects of Milks From Various Animal Types on Infant Fecal Microbiota Through in vitro Fermentations

Frontiers in Microbiology, 2020
Human milk is compatible with infant intestinal microbiota and is vital for infant health. However, most infants do not receive sufficient exclusive breastfeeding, and the effects of including other types of animal milk on the gut microbiota of infants ...
Na Li, Na Li, Bailiang Li, Bailiang Li, Jiaqi Guan, Jiaqi Guan, Jialu Shi, Jialu Shi, Smith Etareri Evivie, Smith Etareri Evivie, Li Zhao, Li Zhao, Guicheng Huo, Guicheng Huo, Song Wang, Song Wang   +15 more
doaj   +1 more source

UiO‐66 metal–organic frameworks in biomedicine: From structural tunability to bioimaging, photodiagnostics, and photodynamic cancer therapy

FEBS Open Bio, EarlyView.
UiO‐66(Zr) metal–organic frameworks are chemically stable, biocompatible, and highly tunable nanomaterials. Their modular structure enables controlled drug delivery, multimodal bioimaging, and light‐activated photodynamic therapy, supporting integrated diagnostic and therapeutic (theranostic) applications in cancer and biomedical research.
Veronika Huntošová, Grigorii Rakhalskii, Miroslav Almáši   +2 more
wiley   +1 more source

The Movement Characteristics of Coal Granular Body in Excavating Rescue Channel in the Collapsed Body

Advances in Civil Engineering, 2018
The collapsed body formed after the underground power disaster is broken into loose body. The mechanical characteristics of the collapsed body are quite different from those of the homogeneous rock mass, and the rescue tunnel is affected by its moving ...
Hao Chuanbo, Liu Zhenwen, Xiao Fukun, Liu Gang, Zhang Rui   +4 more
doaj   +1 more source

The Static Analysis of the Gas Content and the Gas-Dynamic Characteristics at the Second Potash Bed in the Starobinsk Potassium Salts Deposit

Fluids, 2022
The use of the new mining technology on the Third potash bed at the Starobinsk potash salt deposit is accompanied by the displacement of the undermined rocks. The displacement is accompanied by the foliation.
Sergey S. Andreyko, Natalya Litvinovskaya, Artem Papulov, Tamara Lyalina   +3 more
doaj   +1 more source

Molecular characterization of covRS mutations in M1UK Streptococcus pyogenes

FEBS Open Bio, EarlyView.
Group A Streptococcus (GAS) acquires covRS mutations driving a hypervirulent bacterial state, frequently associated with invasive disease‐like necrotizing fasciitis. We demonstrate that the newly emerged M1UK GAS lineage can also acquire these mutations.
Jarrad Pritchard, Emma‐Jayne Proctor, Jiawa Wang, Nikolas P. Johnston, Andrew Hayes, Georgia McCorkell, Haibo Yu, Jai Tree, Mark R. Davies, Mark J. Walker, Ronald Sluyter, Stephan Brouwer, Martina L. Sanderson‐Smith   +12 more
wiley   +1 more source